What is Secondary Hypertension – No Hypertension

Very often the diagnosis of “hypertension” is made erroneously and, accordingly, patients receive improper treatment. As a result, their condition deteriorates significantly, and various complications develop.

This, in particular, often happens when there are errors in the diagnosis and incorrect determination of the causes of high blood pressure. In about 15 cases out of 100, a symptomatic form of arterial hypertension occurs, that is, an increase in blood pressure due to other primary pathologies developing in the human body.

Secondary arterial hypertension is diagnosed when the increase in pressure is caused by a malfunction of the organs involved in its regulation.

This condition is characterized by a severe course, can progress rapidly and significantly worsen the patient’s condition.

This type of hypertension is most often diagnosed in middle-aged people – just then diseases of the internal organs begin to manifest and chronic pathologies become aggravated.

Types of hypertension

The causes of secondary hypertension are many, therefore, the symptoms of the disease in each patient can vary significantly. But there are general features of the development of secondary hypertension:

  1. A sharp and stable increase in blood pressure.
  2. The rapid progression of the disease.
  3. The presence of other diseases.
  4. Weak response to standard treatments.
  5. Sympathoadrenal crises develop.

Identification of the causes of secondary hypertension is necessary to cope with the manifestations of the disease and slow down its course.

If you start to take drugs that lower blood pressure uncontrollably, then resistance may develop to them, which will lead to a more severe course of the disease, and also contribute to the progression of the underlying pathology.

Currently, about 70 different diseases have been identified that can cause secondary hypertension. Therefore, during the diagnosis, all possible factors that can cause symptomatic hypertension are checked, which is often delayed, and as a result leads to a severe course of the disease and disorders of the endocrine system and metabolism.

Hypertensive syndrome is most often caused by:

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Each of the diseases that cause symptomatic arterial hypertension develops completely differently. Therefore, one cannot single out any mechanism for the development of hypertension syndrome.

Secondary hypertension has the same symptoms as the primary form of hypertension. But there is a difference – with symptomatic hypertension, symptoms of the underlying disease causing problems with pressure are more manifested.

The main features can be distinguished:

  • Increased blood pressure.
  • Headache.
  • A feeling of heaviness in the head, squeezing of the temples.
  • Sensation of throbbing in head, tinnitus.
  • The appearance of “flies” in front of the eyes.
  • Redness of the face.
  • Dizziness and weakness.
  • Feeling of nausea.

Secondary hypertension is often accompanied by pain in the heart, swelling of the extremities, weight gain, and other symptoms. The remaining signs depend on the primary disease and the severity of its course.

According to the form of development, 4 states are distinguished:

  1. Transient – pressure rises at times and to low values. There are mild dysfunctions of internal organs without damage.
  2. Labile – hypertension has a persistent course. Mild damage to internal organs is possible.
  3. Stable – persistent hypertension with high rates. There are lesions of the cardiovascular system.
  4. Malignant – has a high risk of complications and an unfavorable prognosis, as it is not amenable to drug therapy.

The remaining symptoms are determined during diagnosis using laboratory tests and instrumental examinations. Only after a complete diagnosis is it possible to determine the severity of hypertension.

Based on the cause of the disease, that is, the organ, the defeat of which caused an increase in blood pressure, several main forms are distinguished.

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Neurogenic hypertension develops when the brain or spinal cord is affected. The most common causes are injuries, tumors, ischemia, cerebral edema, and other types of lesions. In such conditions, not only arterial, but also intracranial pressure rises.

As a result, the following symptoms develop:

  • Severe headaches.
  • Dizziness.
  • Hyperhidrosis.
  • Weakness.
  • Nystagmus
  • Convulsive conditions.
  • Cognitive impairment.
  • Tachycardia.

Diagnosis requires an encephalogram, angiography of blood vessels, MRI and computed tomography of the brain. Only the elimination of the causes will normalize the patient’s condition.


Such hypertension develops when the kidneys are affected due to injuries, tumors, systemic diseases, glomerulonephritis and other inflammatory processes. Secondary nephrogenic hypertension is divided into two forms: parenchymal and renovascular. In rare cases, a mixed form is isolated.

Parenchymal hypertension develops only when a significant part of the kidneys is affected, chronic renal failure develops, or the disease acquires a malignant course. Renovascular hypertension is diagnosed when high blood pressure is caused by kidney disease. The main reason is atherosclerotic vascular damage.

Secondary renal hypertension is accompanied by a persistent course, which rises even more with the use of salty foods. Patients feel intense thirst, fatigue, weakness, and in the evening they observe severe swelling.


Endocrine disorders lead to the fact that the internal glands begin to produce an excessive amount of hormones leading to hypertension. The most common causes of endocrine hypertension are: hypo- and hyperthyroidism, adrenal tumors, pituitary adenoma, Itsenko-Cushing and Kohn syndromes.

Causes of Endocrine Hypertension

In addition to the usual symptoms, the following symptoms join: muscle weakness, panic attacks, abrupt weight gain, heart rate rises, and heart load increases. The main symptoms – headaches, dizziness, weakness – are pronounced.


Hemodynamic or cardiovascular hypertension occurs with damage to large vessels and the heart. In this case, the cause of hypertension is a violation of systemic blood flow, an increase in cardiac output and increased vascular resistance.

  1. Coarctation of the aorta.
  2. Takayasu’s disease.
  3. Aortic insufficiency.
  4. AV blockade.
  5. Sclerosis of the heart arteries.

Characterization of hemodynamic hypertension

Symptoms of hemodynamic hypertension from the cardiovascular system appear differently, depending on the diagnosis. But in addition to the general symptoms, pain and heaviness in the heart, heart rate and pulse disturbances are observed, but hypertensive crises for this form are uncharacteristic.


Symptomatic drug hypertension often occurs against the background of prolonged or improper use of certain medications.

What medications can cause an increase in blood pressure:

  1. Glucocorticosteroids.
  2. Oral contraceptives.
  3. Adrenomimetics.
  4. Tricyclic antidepressants.
  5. Nonsteroidal anti-inflammatory drugs.

Medicines that cause GB

The hypertensive effect of most drugs is based on the retention of sodium, potassium and water in the body or an increase in blood viscosity. This form of hypertension is often diagnosed when a patient has a disease that requires long-term use of drugs.

Principles of therapy

Therapy of the symptomatic form of hypertension does not have a specific scheme. Each patient, depending on the diagnosis, is selected drugs that help cope with the underlying disease. Treatment of hypertension is impossible until the disease that triggered high blood pressure is eliminated.

Most often, conservative treatment is carried out, some patients have to take medications all their lives in order to support the work of internal organs and keep the pressure within normal limits.

What drugs can be prescribed:

  • Calcium channel blockers (Diazem, Diltiazem, Lomir, Cordipine).
  • Beta-blockers (Atenolol, Bisoprolol, Metoprolol, Sotalol, Nadolol).
  • Diuretics (Furosemide, Mannitol).
  • ACE inhibitors (captopril, enalapril, fosinopril).
  • Vascular receptor antagonists (Losartan, Valsartan, Telmisartan).

Medications are selected very carefully, taking into account the characteristics of the patient’s condition. In cases where drug treatment is impossible – with tumors, heart defects, extensive kidney damage – they resort to surgery.

Patients are recommended to have a good sleep, regular rest, proper nutrition and elimination of physical and psycho-emotional stress. Be sure to abandon bad habits, control weight and regularly undergo examinations.

Secondary hypertension or hypertension syndrome has a more severe course than primary hypertension, since the patient’s well-being is significantly complicated by manifestations of the underlying disease.

But at the same time, it is much easier to establish the causes of the symptomatic form of hypertension, provided that the attending physician prescribes a full examination. If you control the course of the underlying disease and take preventive measures, then you can prevent the development of complications and the transition of hypertension to a malignant form.

This pathology often occurs in the form of complications in diseases of internal organs and pathologies of the nervous, endocrine system.

Prophylaxis and prognosis

According to the classification of vascular diseases, doctors distinguish essential – primary and symptomatic – secondary arterial hypertension.

In the second case, we are talking about a steady increase in blood pressure against the background of the underlying disease occurring in the body in a chronic form.

Symptomatic arterial hypertension is prone to systematic relapses, and among dangerous complications with health, doctors do not exclude even the lethal outcome of a clinical patient.

The specified pathology occurs infrequently, it can be an acquired or congenital disease. The pathological process is accompanied by high blood pressure, occurs with damage to internal organs and systems – chronic diseases.

If the causes of primary hypertension are difficult to establish even in a hospital, then the pathogenic factors of secondary hypertension are quite obvious. Normalization of blood pressure is possible only after eliminating the root cause of the underlying ailment.

Symptomatic hypertension is accompanied by tangible jumps in diastolic, systolic blood pressure. The nature and severity of symptoms completely depends on the form of secondary hypertension, and the general signs of this disease are presented below:

  • acute migraine attacks;
  • swelling of the extremities in the morning;
  • dizziness, less often – attacks of vomiting;
  • bouts of tachycardia;
  • noise in ears;
  • goosebumps under the eyes;
  • anxiety, panic attacks.


Secondary hypertension occurs against the background of an attack of the underlying disease, as a serious complication.

For example, with primary pathology of the brain, hypertension of central genesis predominates, which is formed with extensive brain injuries, hemorrhages, impaired central regulation, myocardial infarction, encephalopathy.

Long-term use of drugs can also cause secondary hypertension. The etiology of the pathological process is due to the form of the disease presented below by the classification of pathologies:

  1. Arterial renal hypertension: chronic pyelonephritis, glomerulonephritis, congenital diseases, tuberculosis or polycystic kidney disease.
  2. Endocrine form of hypertension: chronic pathologies of the adrenal gland and thyroid gland, acromegaly, Itsenko-Cushing’s disease.
  3. Neurogenic hypertension: malignant brain tumors, injuries, strokes, aortic coarctation, encephalitis, impaired intracranial pressure, aortic narrowing process.
  4. Cardiovascular form of hypertension: heart failure, congenital heart defects.


Depending on the etiology of the pathological process (primary factor), a conditional classification of secondary arterial hypertension is provided.

This is necessary to simplify the final diagnosis, start timely treatment and eliminate complications, for example, fatal relapse from malignant hypertension.

In order not to once again put your health at risk, you need to be examined in a timely manner.

In this clinical picture, hypertension is caused by chronic pathologies of the kidneys, which are prone to relapse under the influence of pathogenic factors.

So, violations in the renal arteries, polycystic and inflammatory processes are not excluded.

Patients with renal failure at first do not feel pronounced symptoms of hypertension, and more complain of increased fatigue, visual impairment. Types of renal hypertension are as follows:

  • interstitial (associated with relapses of chronic kidney disease);
  • renoprinal (caused by complications after kidney removal);
  • mixed (caused not only by pathologies of the kidneys, but also vessels);
  • renoparenchymal (with damage to parenchymal tissues);
  • Renovascular hypertension (caused by compression of the renal vessels).

The main reason for the jump in Blood pressure is the presence of endocrine pathologies, an imbalance of hormones with subsequent complications.

Arterial hypertension sharply progresses in malignant tumors of the adrenal glands, therefore, delaying the diagnosis is not recommended.

At all stages, the pathology is accompanied by acute pain, and conservative treatment is required to reduce the severity of symptoms. Here are the main types of endocrine hypertension:

An increase in blood pressure is observed against the background of extensive damage to the great vessels and heart.

This occurs with an atherosclerotic attack, stenosis of the vertebrobasilar and carotid arteries, aortic valve insufficiency, aortic coarctation.

Attacks with a hypertensive crisis, which is difficult to correct with medical methods, are not ruled out. Pressure surges in this case are accompanied by acute myocardial pain, the symptoms are similar to the manifestations of other cardiac pathologies.

With neurogenic hypertension, systematic jumps in blood pressure are caused by relapses of the primary cerebrovascular disease with a secondary violation of central regulation.

In this case, we are talking about a progressive stroke, encephalitis, extensive head lesions.

A characteristic ailment is not limited to brain tumors, neurogenic hypertension provokes serious disorders in the central and peripheral nervous system, which, when promptly reacted, are reversible.

With improper use of drugs among potential complications, doctors do not exclude the appearance of jumps in blood pressure. This may be transient (short-term) hypertension, or seizures become protracted.

Such a reaction occurs on the following pharmacological groups of drugs: oral contraceptives, cyclosporin, non-steroidal anti-inflammatory drugs.

Among further health problems, the occurrence of extensive brain pathologies should not be ruled out.


If the doctor suspects chronic kidney pathologies that are accompanied by secondary hypertension, the first thing to do is examine the urine. This is a general analysis, a laboratory study according to Nechiporenko, inoculation to determine the pathogen, the concentration of protein in biological material. Clinically, the diagnostic methods are as follows:

  • Ultrasound of the kidneys and renal arteries;
  • intravenous urography;
  • MRI and CT with vascular contrast.
  • If secondary hypertension has an endocrine form, the recommended diagnostic measures are presented below:
  • urine and blood tests;
  • biochemical analysis for the concentration of thyroid hormones;
  • Ultrasound, MRI of the adrenal glands;
  • diagnosis of the thyroid gland.


Symptomatic hypertension is difficult to treat effectively until the underlying disease can be cured. Otherwise, the positive dynamics of secondary hypertension is marked or absent. Here are the valuable recommendations of specialists, depending on the specifics of the clinical picture:

  • with tumors of the adrenal glands, kidneys, brain, patients have to undergo surgical treatment;
  • in chronic kidney diseases, the intensive care regimen necessarily includes an antibacterial and anti-inflammatory course;
  • if the cause of secondary hypertension is endocrine disorders, hormonal levels will have to be adjusted with medical methods;
  • with hemodynamic hypertension with congenital heart defects, the patient will undergo cardiosurgical treatment, conservative correction of heart failure.
  • when the cause of secondary hypertension becomes the wrong intake of drug groups, effective therapy starts with the abolition, correction of those.

With transient hypertension, the doctor recommends conservative methods for solving health problems that can reduce the number of seizures, stabilize blood pressure, and extend the period of remission. Along with intensive therapy of the primary disease, complex antihypertensive therapy is recommended, which includes the following pharmacological groups:

  • ACE inhibitors: Captopril, Enalapril, Fosinopril;
  • calcium channel antagonists: Verapamil, Kordafen;
  • β-blockers: Timolol, Pindolol;
  • diuretics: Furosemide, Indapamide;
  • antihypertensive drugs of central action: Moxonidine.

With transient hypertension, surgery is not required, and the patient requires prevention of the development of renal failure.

The operation is performed if malignant or benign tumors develop that provide jumps in blood pressure, extensive vascular pathologies occur.

The doctor determines the medical indications and the type of surgical measures taking into account the patient’s age, the nature and severity of the prevailing diagnoses.


To avoid secondary hypertension, it is important not only to control blood pressure, but also to timely treat the underlying diseases of your own body. To do this, non-specific preventive measures have been developed, which the doctor informs his patients, especially at risk. Here are some preventive measures you need to adhere to:

  • avoid stressful situations;
  • to make walks in the fresh air;
  • control weight and metabolism;
  • give up harmful habits;
  • reduce salt intake.

The information presented in the article is for guidance only. Materials of the article do not call for independent treatment. Only a qualified doctor can make a diagnosis and give recommendations for treatment based on the individual characteristics of a particular patient.

Secondary arterial hypertension is a chronically elevated pressure that accompanies a disease of various organs and systems of the body. A thorough diagnosis allows you to determine the cause of the syndrome and prescribe an effective treatment for the underlying disease with correction of blood pressure.


The hidden danger of secondary hypertension is that not everyone is aware that they are faced with it. An increase in pressure does not necessarily cause pronounced painful sensations. Meanwhile, the disease undermines the body, gradually leading to diseases of the kidneys, angina pectoris, myocardial infarction.

Therefore, you should pay attention to the following symptoms:

  • sometimes it gets dark in the eyes, “flies” appear, double vision;
  • nape pain, tinnitus, speech disorder;
  • arms and legs may become numb, and swell in the evening;
  • unreasonable chills or sweating.

The international classification ICD-10 distinguishes several varieties of secondary hypertension, depending on its cause (etiology):

  • Renovascular hypertension
  • associated with kidney damage;
  • caused by endocrine disorders;
  • due to other factors;
  • unspecified

Secondary arterial hypertension – classification, manifestations, methods of therapy and prevention

In the international classification, you can find the following symptoms of the disease:

  • dizziness;
  • pain in the head;
  • “Flies” before the eyes;
  • rapid pulse;
  • noise in ears;
  • swelling, especially in the morning;
  • irritability;
  • sense of anxiety;
  • weakness;
  • nausea.

Both primary and secondary hypertension have a common symptom – this is high blood pressure. With a symptomatic form, not all signs of pathology may appear. Sometimes it can be manifested only by increased pressure. The most pronounced signs can be seen in patients with neurogenic hypertension.

If the increase in pressure is caused by problems in the functioning of the renal system, then the patient has visual impairment and headaches. At the beginning of the development of the disease, the pathological process may not make itself felt. A person may feel a slight malaise, which most attribute to fatigue. Although at this moment a dangerous ailment arises, which must be treated in a timely manner.

Every person suffering from chronic diseases must be familiar with the signs inherent in secondary hypertension. Thanks to this knowledge, he will be able to protect himself from dangerous complications, which can lead to frequent cases of high blood pressure.

It is important to learn to distinguish the primary form from the secondary. The latter has some features:

  • traditional remedies do not help relieve pressure;
  • Blood pressure rises suddenly;
  • violation is characteristic of young people from 20 years of age and pensioners after 60 years;
  • high blood pressure is steady;
  • sympatho-adrenaline crises may occur.

An accurate diagnosis can only be made by a specialist after examining a person who has complained of ill health.

A distinctive feature of the secondary form of the disease is the inability to reduce pressure with conventional drugs.

The causes of secondary hypertension are divided into several groups. They depend on what disease provoked an increase in pressure:

  1. In renal hypertension – stagnation of fluid in the body, impaired blood flow in the kidneys and narrowing of the arteries.
  2. With endocrine hypertension – acromegaly, adrenal gland disease, thyroid problems.
  3. With the neurogenic form – encephalitis, trauma, stroke, increased intracranial pressure, brain tumors.
  4. With a cardiovascular form – heart defects, aortic damage, heart failure.
  5. The dosage form of hypertension arises during the administration of antidepressants, oral contraceptives with estrogens, glucocorticoids.
  6. A frequent cause of high blood pressure is alcohol abuse, so chronic alcoholism can be attributed to the pathology.
  • proper nutrition;
  • body weight control;
  • quitting alcohol and smoking;
  • in the presence of a predisposition to diseases leading to secondary hypertension, it is necessary to regularly undergo examinations with specialized doctors.

Another preventive measure is the constant monitoring of blood pressure with an existing disease, and its timely correction.

Constant high blood pressure is a serious disease if you do not fight it. Secondary arterial hypertension, as a rule, passes along with the pathology that caused it. That is why it is important to find the root cause of high pressure. This may take some time. But the effectiveness of further therapy depends on the correct diagnosis.


Secondary arterial hypertension is a pathological condition caused by a malfunction of the internal organs that are involved in the regulation of blood pressure. Distinguish from essential hypertension in that it is possible to establish the causes.

This type of disease in most cases has a malignant and progressive course, practically does not lend itself to medical correction of antihypertensive drugs. All the time, a high and persistent blood “pressure” is revealed.

Scientists distinguish more than 70 different pathologies that can lead to the development of symptomatic disease. A differential diagnosis is required. But finding the exact etiology requires a lot of time, which leads to severe damage to the target organs.

Secondary hypertension accounts for up to 25% of cases of all ailments. For a favorable prognosis, it is necessary to establish the pathophysiology of the abnormal process in a short time, to eliminate it with the help of adequate treatment.

In accordance with the International Classification of Diseases (ICD-10 code), arterial hypertension is a group of pathological conditions due to which chronically high blood pressure values ​​are diagnosed. The list of these ailments is quite extensive.

Secondary hypertension may be caused by taking certain medications. These include contraceptives for oral administration, non-steroidal anti-inflammatory drugs, pills for the treatment of cardiovascular diseases.

If the increase in blood pressure is due to the primary pathology of the brain, then a diagnosis of central hypertension is made. Usually it develops due to brain injuries, a violation of central regulation. Other causes: cerebral hemorrhage, heart attack, encephalopathy.

The mechanisms of development of renal hypertension lie in impaired renal function:

  • The renal arteries are affected. This reason is most common. The kidneys play a dominant role in the regulation of diabetes and DD. If they receive a small amount of blood, they produce components that increase systemic blood pressure to provide renal blood flow. The causes of blood circulation disorders are different: atherosclerotic changes, thrombosis, tumor neoplasms.
  • Polycystic kidney disease is a genetically determined pathology that provokes gross transformations in the form of a large number of cysts, which leads to impaired organ function up to a severe form of renal failure.
  • A prolonged course of inflammatory processes in the kidneys. For example, a chronic form of pyelonephritis. Such a disease is rare, but not excluded.

Endocrine hypertension develops as a result of an endocrine disorder. The pathogenesis is as follows:

  1. Itsenko-Cushing’s disease. The etiology is based on the destruction of the adrenal cortex, which leads to increased production of glucocorticosteroids. As a result, a person increases the load inside the blood vessels, there are characteristic signs of the disease.
  2. Pheochromocytoma is a pathology that affects the adrenal medulla. In medical practice is relatively rare. Usually leads to hypertension of a malignant and progressive course. Due to compression of the tumor, the release of adrenaline and norepinephrine into the blood is observed, which leads to a chronically high diabetes and DD or a crisis course.
  3. Cohn’s disease – a tumor located in the adrenal glands, provokes an increase in the concentration of aldosterone. Hypokalemia, an increase in blood pressure develops. Feature: drugs of hypotensive effect practically do not work.
  4. Violation of the thyroid gland.

Cardiovascular hypertension is caused by many diseases. These include congenital narrowing of the aorta, open ductus arteriosus, aortic valve insufficiency, late stages of chronic insufficiency.

Very often, secondary degrees of arterial hypertension appear against the background of a malfunction in the kidneys. This state is characterized by a stable high blood pressure, which is caused by a violation of blood circulation in the organs.

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Allocate factors affecting the development of the disease. By correcting them, blood pressure is normalized.

In 10% of cases, high blood pressure is a symptom of other diseases that affect blood circulation and heart function. Normalization Blood pressure in this case depends on the successful treatment of the underlying disease.

Forms of the disease

Form of hypertension Description and symptoms
Primary arterial hypertensionI degree – 140–159 / 90–99 mm Hg. Art. Hopping HELL. It rises and quickly bounces back without consequences.

Hypertensive crises occasionally occur, target organs are not affected.

II degree – 160–179 / 100–109 mm Hg. Art. Jumps Blood pressure is sometimes replaced by periods of decline.

Sharp and prolonged attacks often occur, target organs are affected.

III degree – 180/110 mm Hg. Art. and higher. Complications arise in the form of atherosclerosis, heart disease. Target organs (kidneys, brain, eyes, heart) are severely affected.

Secondary hypertensionDepending on the underlying disease, there may be renal, endocrine, hemodynamic and neurogenic hypertension. Drug or surgical treatment is aimed at the affected organ, and not at lowering the pressure.

It develops as a sign of kidney damage, which is always accompanied by a violation of blood supply. In kidney diseases (glomerulonephritis, pyelonephritis, stones, tumors, prolapse) sodium accumulates in the cells. It retains excess fluid in the walls of blood vessels, narrowing them. Spasm and hypertension occur.

Detects disorders of the endocrine glands. Including thyrotoxicosis, pheochromocytoma, hyperthyroidism, primary hyperaldosteronism (Conn syndrome). With a decrease in the activity of the gonads, pressure also increases. Increased intake of hormones in the blood provokes narrowing of the arteries and cause the development of the disease.

Traced with atherosclerosis, coarctation of the aorta. The cause of the increased pressure is plaque or the difference between the blood supply to the lower and upper parts of the body.

It is observed with damage or inflammation of the spinal cord and brain. For example, tumors, injuries, bulbar polio, encephalitis. The vessels are compressed, and the pressure rises.

Primary (essential) hypertension develops due to a violation of the tone of the arteries, which leads to an increase in blood pressure. Various external circumstances affect vascular tone.

Pulmonary hypertension

Secondary pulmonary hypertension is a pathology in which pressure in the arteries of the lungs rises. The result is a narrowing of the lumen in the vessel of the lung. The reason for this is the complex structure of the pulmonary arteries. The disease most often occurs in middle-aged women. In men, it is diagnosed three times less.

At the first stages, the disease does not manifest itself in any way, a person may not even guess about its presence until there is a hypertensive crisis, hemoptysis and swelling of the lungs. That is, when the development of secondary pulmonary hypertension takes a severe form, and this greatly complicates the treatment.


The renal form of the disease is considered the most common. It is found in the vast majority of cases, more than 80%. Pathology develops due to damage to the kidneys, which can be either congenital or acquired, as well as with pathologies of the arteries that feed the kidneys.

How severe the disease will be depends on how quickly the renal artery becomes clogged and how the disease itself occurs, which caused an increase in blood pressure. At the initial stages, there may not be signs of hypertension.

Secondary renal hypertension will begin to manifest itself only after a severe damage to the kidney tissue occurs. Fear of rising blood pressure is in patients with a diagnosis of pyelonephritis. With inflammation in the renal pelvis, the risk of pressure problems is very high. Glomerulonephritis can lead to the same diagnosis. This disease is also contagious.

Often you can see symptomatic hypertension in young patients. If the pathology is not cured in time, then the development of renal failure is inevitable. It is also worth noting that with infectious forms of the disease, the risk of severe hypertension is 12%.

Endocrine hypertension

This form of secondary hypertension develops amid problems with the endocrine glands. Often, pathology is diagnosed in people with thyrotoxicosis. This is a thyroid disease, which is expressed as an increased secretion of the hormone thyroxine. With such a violation, an increase in systolic pressure is observed, and diastolic blood pressure is normal.

Diseases of the endocrine system in which hypertension develops:

  • Feochromocytoma: the main sign of an adrenal tumor is an increase in blood pressure. In this disease, the pressure is either stably high or paroxysmal.
  • Conn’s syndrome: due to the increased secretion of the hormone aldosterone in the body, sodium begins to linger, and a secondary form of hypertension develops.
  • Itsenko-Cushing’s syndrome. Most patients with this pathology suffer from high blood pressure. It is recognized by specific changes in the body: the body becomes denser, and the face is puffy. In this case, the limbs remain normal.
  • Climax During the extinction of female sexual functions, jumps in blood pressure often occur.

The endocrine form of hypertension responds well to therapy, if you start it in a timely manner.

Hemodynamic hypertension

Diseases of the cardiovascular system lead to a secondary hemodynamic form of hypertension. These include:

  • atherosclerosis;
  • mitral valve disease;
  • heart failure;
  • narrowing of the aorta;
  • systolic hypertension.

As a rule, none of these pathologies is the only cause of increased pressure. Most often, the disease develops against the background of two pathological processes. For example, renal artery stenosis and a chronic form of pyelonephritis.

Drug hypertension

Improper medication can also trigger high blood pressure. Certain groups of drugs have this pathology in the list of side effects and complications. With this form of hypertension, pressure surges can be paroxysmal or protracted.

Such reactions result from the use of the following drugs:

  • anti-inflammatory nonsteroidal agents;
  • oral contraceptives;
  • “Cyclosporin.”

With prolonged use of such medications, the patient may worsen. It also threatens the development of extensive brain pathologies.

Symptomatic arterial hypertension: causes of pathology, >

Diagnostic studies of secondary arterial hypertension consist of several standard procedures. Pathology is recognized by systolic and systolodiastolic murmurs that can be heard in the epigastric region. Such a symptom most often indicates the presence of renal artery stenosis.

In order to measure pressure, the patient must be in a standing position, and then lying down. Indicators are measured in two states: first at rest, and then at the end of physical activity. Due to the difference between blood pressure indicators, a specialist determines a number of secondary symptoms that occur with this type of hypertension.

The following procedures are also performed: ultrasound, scintigraphy, dopplerography and the condition of the arteries is studied. If renal hypertension is suspected, additional tests and studies may be prescribed. Be sure to give up blood, urine and a tank test, indicating a bacterial infection. In some forms of secondary hypertension, CT and MRI can be prescribed. If a tumor develops in the body, a biopsy is mandatory.

With any type of symptomatic hypertension, a referral to an ophthalmologist is issued. This is due to the fact that pathology can lead to damage to the eye retina.

Symptomatic hypertension or secondary is a determining or background sign of another underlying disease that is not immediately established.

The recorded clinical manifestations of secondary pathology consists of signs of a major chronic illness, periodic pressure surges and changes in well-being. In some cases, in the patient’s history, high blood pressure is the only symptom of the primary pathology. As a rule, patients pay attention to the following state changes, which are repeated periodically:

  • dizziness;
  • pain, discomfort in the heart;
  • weakening, fatigue;
  • periodic jumps in temperature;
  • pain in different parts of the head, occurs unexpectedly;
  • nausea, sometimes vomiting, is noted;
  • psycho-emotional disorders, a person may experience a sharp excitement or apathetic state, which appear after a crisis;
  • less often, patients have fear, a sense of anxiety, blanching of the skin, causeless tachycardia, excessive sweating.

The secondary type of pathology can be identified by specific symptoms, it manifests itself at any age in the range of 20-60 years, against the background of typical concomitant diseases. Symptomatic blood pressure can be determined by the following signs:

  • pressure indicators are steadily increased;
  • jump Blood pressure is always sharp;
  • rapid progress;
  • complications develop;
  • malignancy of the process;
  • the disease progresses rapidly;
  • severe headaches;
  • sensation of pulsation of blood vessels;
  • chest pains;
  • heart rhythm disorder.


Secondary hypertension develops against the background of pathologies of internal organs, therefore, the mechanism that causes the development of symptomatic hypertension will be individual for each patient. The following common causes of the appearance of symptomatic hypertension are distinguished:

  1. Renal abnormalities that provoke ischemic processes in the tissues of the organ. This condition provokes a decrease in the activity of depressant (those that suppress the increase in pressure) renal agents. There is an increase in hormone levels due to endocrine changes and this leads to an increase in blood pressure.
  2. Damage to the structures of the nervous system leads to the appearance of ischemic sites in the centers that are responsible for the regulation of blood vessels.

Separately, hemodynamic secondary arterial hypertension, which is represented by combined changes, is isolated. They occur in the heart muscle and large vessels of the circulatory system. There are several main deviations:

  • excessive filling of arteries, this section is located above the pathological area of ​​narrowing;
  • dysfunction of depressive zones, lowering the elasticity of the walls of blood vessels;
  • the normal diameter of the vessels decreases, due to an increase in blood volume;
  • speed increases, the amount of blood passed through the aorta with an increase in its flow to the heart.


A sharp or gradual formation of secondary hypertension occurs due to the presence of other diseases. Doctors decided to divide the etiology of the origin of the disease into four large groups:

  1. Neurogenic causes. This includes traumatic pathologies and diseases of the nervous system: bruises, malignant tumors, stroke, polyneuropathies, inflammatory processes. Symptomatic hypertension with the appearance of brain cysts, tumors in the area of ​​the optic tubercle is called Penfield syndrome.
  2. Nephrogenic. Often, pyelonephritis, hydronephrosis, lupus, glomerulonephritis, and polynephrosis are diagnosed as the root cause. The changes occurring in the vessels of the kidneys are also referred to this group: dysplasia, atherosclerosis, aneurysms, tumor-like neoplasms. Removal of a kidney or abnormality in the structure of an organ can lead to the development of hypertension.
  3. Endocrine. This group includes disorders of the thyroid gland, pathology of the adrenal cortex, pituitary dysfunction: hypothyroidism, pheochromocytoma, Itsenko-Cushing’s disease, acromegaly. This group is characterized by decreased hormone production during the menopause.
  4. Hemodynamic. This group includes acquired or congenital anomalies of large vessels, heart tissues.

This classification is not complete, these are the largest groups that are often found in diagnosing a disease.

There is another series of pathologies that are less likely to cause symptomatic hypertension.

For example, a persistent increase in blood pressure can provoke drug treatment, sometimes the reason is the use of contraceptives, medications based on heavy metal salts, glucocorticosteroids, indomethacin.

There is a division into several stages of the development of pathology. Secondary arterial hypertension is classified depending on the condition of internal organs and the severity of hypertension:

  1. Transient. The pressure rises periodically and not to high rates. Damage to internal organs is absent.
  2. Labile form. Persistent high blood pressure, there is a slight damage to the internal organs (vessels of the ocular fundus, heart).
  3. Stable hypertension. High rates of persistent high blood pressure, there is hypertrophy of the left ventricle, there is a pronounced change in the vessels of the fundus. These changes occur due to stable increased pressure, which increases the load on the heart and blood vessels.
  4. Malignant form. Stable high blood pressure, uncontrollable, antihypertensive drugs do not work. Patients have a high risk of cardiovascular complications (heart attack, stroke).


The examination begins with an examination, the doctor interviews in detail and correctly examines the patient. During the conversation, the doctor notes the previously occurring pathologies, including childhood diseases, infections, injuries.

Blood pressure is measured several times at home and in a hospital setting, it hurts to constantly fix it, record indicators.

There are certain conditions for taking indicators, there are situations in which data can be considered questionable. For the diagnosis, the following tests are prescribed:

  1. Urine. Be sure to carry it out, it helps to determine the number of red blood cells, protein and white blood cells. If their number is higher than normal, then there are problems with the kidneys.
  2. Blood. Check for the presence of anemia, indicators of creatine, lipids, total protein, urea, hypokalemia, hormone levels.
  3. Ultrasound of the tissues of the heart, kidneys, blood vessels.
  4. ECG.
  5. Angiography of blood vessels.
  6. CT scan.

The essence of therapy with a diagnosis is the optimal treatment regimen for the main cause, which caused an increase in blood pressure, the elimination of symptoms.

For this, the doctor should prescribe, based on the analyzes, different groups of antihypertensive drugs, registered levels of blood pressure are necessarily taken into account.

When selecting medicines, the doctor takes into account contraindications for the main pathology, possible side effects, because some drugs may have a conflict with a defining ailment.

It is possible to effectively reduce high blood pressure with a change in lifestyle principles.

Refusal of bad habits, optimal diet, normalized physical activity and getting rid of excess weight – all this will have a positive effect on the normalization of the tonometer.

If the main pathology is a brain tumor, adrenal cyst, atherosclerotic plaques, then surgical intervention is indicated.


Symptomatic arterial hypertension, depending on the form and severity of the pathology, may have a different expected outcome.

With the timely detection of pathology in most people, drug therapy gives good results with a positive prognosis. The transient form is characterized by easily adjustable high blood pressure.

The clinical picture is not bright, you can regulate the condition with the help of medications.

An unfavorable prognosis is given for kidney damage, this often leads to malignant hypertension, which has a yard of dangerous complications. A negative outcome will be in the pathology of blood supply to the brain, kidney failure.

In this case, a fatal outcome is predicted for 1,5 years. It will depend on the degree of influence of hypertension on the work of the kidneys.

If symptomatic hypertension developed against the background of menopause, Cushing’s syndrome, and the cardiovascular system, a favorable outcome is often observed.


For the treatment of symptomatic hypertension, medication is most often prescribed. In some cases, it is combined with surgical intervention. Therapy with drugs helps to reduce the number of attacks of hypertension, normalize blood pressure and prolong remission. For this, such drugs are prescribed as:

  • “Moxonidine” and similar antihypertensive agents.
  • “Verapamil”, “Kordafen” are calcium channel antagonists.
  • “Enalapril”, “Fosinopril” – ACE inhibitors.
  • “Timolol”, “Pindolol” – beta blockers.

Medications give a positive effect when combined with each other, only a doctor can prescribe a complex for admission, after all the examinations have been completed.

Detonic – a unique medicine that helps fight hypertension at all stages of its development.

Detonic for pressure normalization

The complex effect of plant components of the drug Detonic on the walls of blood vessels and the autonomic nervous system contribute to a rapid decrease in blood pressure. In addition, this drug prevents the development of atherosclerosis, thanks to the unique components that are involved in the synthesis of lecithin, an amino acid that regulates cholesterol metabolism and prevents the formation of atherosclerotic plaques.

Detonic not addictive and withdrawal syndrome, since all components of the product are natural.

Detailed information about Detonic is located on the manufacturer’s page www.detonicnd.com.

Svetlana Borszavich

General practitioner, cardiologist, with active work in therapy, gastroenterology, cardiology, rheumatology, immunology with allergology.
Fluent in general clinical methods for the diagnosis and treatment of heart disease, as well as electrocardiography, echocardiography, monitoring of cholera on an ECG and daily monitoring of blood pressure.
The treatment complex developed by the author significantly helps with cerebrovascular injuries and metabolic disorders in the brain and vascular diseases: hypertension and complications caused by diabetes.
The author is a member of the European Society of Therapists, a regular participant in scientific conferences and congresses in the field of cardiology and general medicine. She has repeatedly participated in a research program at a private university in Japan in the field of reconstructive medicine.