Tissue microcirculation improving drugs

Damage to the blood circulation in the lower extremities is caused by damage to the veins and arteries (atherosclerosis), endarteritis, varicose dilated veins, narrowing of the vessel lumen with cholesterol plaques, inflammation of the vessel walls or its spasm. If suddenly on the foot appeared blue “stars” or grids of thin vessels, these are signs of varicose veins, which can manifest themselves as pain and heaviness in the legs, night cramps, swelling, knots and bloating on the affected vessels.

The skin on the legs may redden and thin. Impaired blood circulation in the lower extremities is manifested by arching calf pain, heavy legs, intermittent claudication. More serious symptoms are thrombosis, trophic ulcers, indicating the development of thrombophlebitis.

Vasodilator drugs

The scope of vasodilating elements is extensive. They are used in the treatment of various pathologies of peripheral circulation:

  • varicose veins;
  • with atherosclerosis;
  • angioedema.

Below we consider the most commonly prescribed medications.

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Myotropic antispasmodic pronounced vasodilating action. Available in tablets and in solutions for intramuscular and intravenous administration. The active substance is bencyclan fumarate. It is prescribed for the treatment of diseases of the peripheral circulatory organs, chronic arterial pathologies and for relieving spasms in systems and tissues.


This synthetic drug restores impaired circulation. The active substance is vinpocetine. It has antioxidant, antiepileptic and neuroprotective effects, as well as dilates blood vessels and relieves inflammation. It is prescribed for the treatment of many vascular diseases, including those with impaired motor activity associated with cerebrovascular insufficiency.


Nootropic combination drug, which also has vasodilating properties. It is used for cerebrovascular insufficiency, prevention of migraines, Parkinson’s disease of vascular etiology and other pathologies of blood supply to the brain, and as a vasodilator for the legs, it is used only as part of complex therapy as prescribed by the doctor.

The active substance is warfarin. This drug is indicated in the treatment and prevention of thrombosis and thromboembolism. It is an anticoagulant of indirect action. The decrease in coagulability does not occur due to the influence of the drug itself, but due to its pharmacological effects in the body, that is, in a secondary way.


This medication is recommended by doctors to treat veins. The therapeutic effect of the components extends mainly to the limbs. The main effect is aimed at improving the tone and elasticity of venous vessels and the removal of foci of stagnation of blood. Supporting actions are:

  • improvement of lymphatic drainage;
  • regulation of general blood circulation;
  • decrease in vascular permeability;
  • regulation of the quality of white blood cells.

With the right doses, the drug has a directed and complex effect on the circulatory system. It has minor contraindications, which the doctor will take into account when appointing.


A complex drug, in which caffeine and ergot alkaloids. It is used for pathologies of cerebral and peripheral blood circulation. The instructions for use say that it is able to increase the tone of the veins and restore the permeability of capillaries.


As part of this tool contains an extract of ginkgo biloba leaves. Available in capsules of 40, 80 and 120 mg. The herbal preparation is able to improve cerebral microcirculation, slightly dilates blood vessels, increases tissue resistance to hypoxia and reduces the ability of platelets to aggregate. The most effective drug acts on the veins and arteries of the hands, feet and cerebral vessels. The active substances of the drug also work as antioxidants.

If the functioning of the central nervous system worsens, doctors prescribe drugs to patients to improve blood circulation in the brain. Improved blood flow normalizes metabolic processes in the brain tissue.

This effect is produced by tablets from spasm of cerebral vessels. Medicines that evenly dilate blood vessels throughout the human body, relieve headaches, produce a calm, not sharp effect. Because the expansion is distributed throughout the body.

By decreasing the concentration of calcium ions, these drugs significantly expand the vessels of the brain and heart. The mechanism of their action is that they slow down the penetration of positive calcium ions with valency 2 into the muscle cells of blood vessels and the heart. In this case, slow L-type calcium channels are used. The coronary and peripheral arteries, arterioles expand.

Vascular drugs to improve blood circulation can increase blood flow to the brain tissue, improve the blood supply process. The pharmacological action allows you to cope with oxygen starvation, a lack of nutritional components.

Causes of circulatory disorders

In people with diabetes, the lower limbs hurt due to blockage of the vessels with atherosclerotic plaques. The insufficient clearance of capillaries that underwent pathological changes does not allow sufficient supply of tissue to the blood.

Therefore, they experience severe discomfort due to a lack of nutrients, oxygen and send a kind of signal for help in the form of pain manifestations.

Atherosclerosis of the lower extremities develops due to the high sugar content in the bloodstream. The concentration of glucose negatively affects the circulatory system, putting off excess substances on the walls of blood vessels, weakening them and depriving them of elasticity. The disease creeps up gradually, and can go unnoticed for many years.

Knowing the pathology in time will help knowledge of its main symptoms, manifested at different stages of the disease:

  • the skin on the patient’s legs thickens, gains shine;
  • nails become brittle;
  • hair loss in the leg region is observed;
  • partial atrophy of the muscles of the legs;
  • sores on the heels and toes are possible;
  • sometimes gangrene of the fingers develops;
  • in the lower extremities there are sensations of pain or tingling (numbness, weakness) during walking or physical exertion;
  • feeling of chilliness and coldness in the legs;
  • cramps in the calf muscles;
  • discoloration of the skin of the legs (excessive pallor, redness).

Often, patient complaints may be non-specific or completely absent. In half the cases, vascular pathologies of the lower extremities do not manifest themselves. They can be diagnosed only during the examination. If treatment is not started in a timely manner, surgical correction of the disease may be required, that is, amputation of one of the limbs.

The main reason leading to impaired circulation of blood in the lower extremities, is a sedentary lifestyle. By the nature of their activities, most people are often in a sitting position, which leads to stagnation of blood in the veins. There is pain in the legs, they start to get tired quickly and become cold.

Many people, especially the elderly, constantly experience a slight chilliness, but after a short walk it becomes hot. This is explained by the fact that even such a small exercise increases blood circulation, eliminating the cold feet syndrome.

How to improve blood circulation in the legs? In this case, no special treatment is required, just enough to change your lifestyle a little. If you start to move more, the disease is able to pass on their own, and simple morning exercises will help improve the overall condition of the body.

Other causes can also lead to impaired blood circulation in the lower extremities, and not so harmless. Such a pathological condition may be a sign of a malfunctioning of any organ. That is why it is not easy to understand what specifically contributed to the development of the disease and what kind of treatment is required.

The following are the most common causes of circulatory disorders in the legs:

  • alcohol and smoking;
  • age changes;
  • high content of cholesterol in the blood;
  • ischemia, atherosclerosis;
  • diabetes;
  • hypertension;
  • overweight;
  • varicose veins, thrombosis and stenosis of arteries.

The following types of circulatory disorders are found:

  1. Blood overflow of tissues. The skin in such areas is red and warm to the touch. This condition appears when exposed to various factors: toxins, allergens and products of inflammation.
  2. When the outflow of blood worsens in a certain organ, then it overflows. Tissues acquire a bluish tint, this is due to blockage of the veins or due to weak work of the heart muscle.
  3. Inadequate blood supply or, as they call this condition, ischemia. The reasons are all the same obstruction of the arteries. The result of this violation is pain due to insufficient intake of blood and, accordingly, oxygen and nutrients.
  4. Slow blood flow or its complete stop in small branches of veins. The causes of this pathological condition can be various poisoning by poisons, chemicals, too high or, conversely, low temperatures.
  5. Thrombosis can occur with the formation of blood clots that impede the normal flow of the main body fluid through the veins and arteries. Tissues become swollen and cyanotic.
  6. Embolism. A condition in which clogging of the vascular lumen by various particles occurs: fatty components, gases, and tiny organisms.

Diseases caused by impaired blood flow:

  • varicosity;
  • thrombophlebitis;
  • ischemia;
  • Raynaud’s disease;
  • thromboembolism.

Anxiety symptoms arising from circulatory disorders:

  • pain in the legs, heaviness and discomfort;
  • bluish tint;
  • edema;
  • hearing impairment;
  • headache;
  • disorders of memory and coordination of movements;
  • numbness;
  • problems with swallowing;
  • speech disorders;
  • feeling of chilliness in the limbs;
  • blanching of the hands or feet;
  • deterioration of vision.

With all of the above symptoms, you should immediately consult a doctor.

The basis of such violations are processes of damage to the vascular wall, as a result of which its permeability increases. Blood stasis develops and the exit of its liquid part into the pericellular space, which leads to compression of the small capillaries by an increased volume of intercellular fluid, and the exchange between cells and capillaries is disrupted.

So, the main pathological conditions that lead to disruption of blood flow in the vessels of the microvasculature are:

  • Pathology of the central organs of the circulatory system – acute and chronic heart failure, all types of shock (traumatic, pain, due to blood loss, etc.), myocardial ischemia, venous hyperemia (an increase in blood volume and its stagnation in the venous part of the bloodstream).
  • Pathological changes in the ratio of the liquid and cellular parts of the blood – dehydration or, conversely, an increase in the volume of the liquid part of the blood with excess fluid intake into the body, DIC, with increased thrombosis in the lumen of the vessels.
  • Vascular wall diseases:
  • Vasculitis (literally, vascular inflammation) – primary hemorrhagic, vasculitis in autoimmune diseases (systemic lupus erythematosus, rheumatoid arthritis, rheumatism), vasculitis in hemorrhagic fevers and bacteremia (sepsis – the penetration of bacteria into the bloodstream and generalization of infections),
  • Atherosclerosis of the large and small arteries, when atherosclerotic plaques are deposited on the inner wall of the vessels that impede the normal flow of blood,
  • Damage to the vascular wall and the attachment of blood clots to it with diseases of the veins – with thrombophlebitis and phlebothrombosis,
  • Diabetes mellitus, in which there is a toxic effect of excess glucose on the inner lining of blood vessels, ischemia (insufficient blood flow) of soft tissues develops.

Calcium antagonists

This category of drugs has long been used to stabilize cerebral circulation. In the modern industry of pharmacology, the 3rd generation of these drugs is manufactured. Calcium antagonists increase the diameter of the artery, do not change the tone of the venous vessels. After their components enter the body, cerebral blood flow is stimulated, many micronutrients enter the body.

Calcium antagonists are divided into the following subcategories: Dihydropyridines, Phenylalkylamines, Benzothiazapines. After the development of drugs of the 2nd generation, their list is expanding.

Causes of Microcirculation Disorders

Violations of blood microcirculation can occur in any organ. However, the most dangerous is the defeat of the capillaries in the heart muscle, in the brain, in the kidneys and in the vessels of the lower extremities.


typical causes of impaired blood supply to the heart muscle (myocardium)

Disorders of microcirculation in the heart muscle indicate the development of myocardial ischemia, or coronary heart disease. This is a chronic disease (IHD), the danger of which is in the development of acute myocardial infarction, often with a fatal outcome, as well as in the formation of chronic heart failure, which leads to the fact that the heart is not able to provide blood to the whole body.

The initial symptoms of a blood flow disorder in the myocardium include signs such as increased fatigue, general weakness, poor tolerance of physical exertion, shortness of breath when walking. At the stage when severe myocardial ischemia develops, pressing or burning pains appear behind the sternum or in the projection of the heart on the left, as well as in the interscapular region.

Microcirculatory disorders in the vessels of the brain appear due to acute or chronic disorders of cerebral circulation. The first group of diseases includes strokes, and the second develops as a result of long-existing arterial hypertension, when the carotid arteries that feed the brain are in a state of increased tone, as well as due to damage to the carotid arteries with atherosclerotic plaques or due to severe osteochondrosis of the cervical spine when the cervical vertebrae render pressure on the carotid arteries.

cerebral ischemia due to circulatory disorders

Symptoms of DEP include changes in cognitive and mental functions, disturbances in the emotional spectrum, forgetfulness, especially loss of household memory, resentment, tearfulness, dizziness, unsteady gait, and other neurological symptoms.

Disorders of microcirculation in the vessels of the kidneys can occur due to acute or chronic processes. So, with a shock condition, blood does not enter the blood vessels of the kidneys, as a result of which acute renal failure develops. In chronic processes in the kidneys (arterial hypertension, vascular damage in diabetes mellitus, pyelonephritis and glomerulonephritis), capillary blood flow disorders develop gradually, throughout the entire period of the disease, and are clinically manifested, as a rule, by insignificant symptoms – rare urination, nocturia (nighttime urination) ), swelling on the face.

An acute condition is manifested by the absence of urine (anuria) or a sharp decrease in its amount (oliguria). Acute renal failure is an extremely dangerous condition, since without treatment, the body is poisoned by its own metabolism products – urea and creatinine.

Lower limbs

Microcirculatory disorders in the vessels of the lower extremities most often develop due to acute thrombosis of arteries or veins of the lower extremities, as well as in diabetic angiopathy – damage to the microvasculature in patients with high blood glucose levels. In addition, disorders of capillary blood flow in the muscles of the legs and feet occur in smokers due to the constant spasm of the vessels of the corresponding vessels and are clinically manifested by the syndrome of intermittent claudication.

Acute blood flow disorders during thrombosis are manifested by a sharp swelling, blanching or turning blue of the limb, and severe pain in it.

Chronic microcirculatory disorders, for example, with varicose veins of the lower extremities or diabetic angiopathy, are characterized by periodic pain, swelling of the feet, and a violation of the sensitivity of the skin.

The diabetic foot syndrome deserves special attention. This is a condition that develops as a result of prolonged damage to the vascular wall by non-digestible glucose by the cells, as a result of which macro- and microangiopathy (vascular pathology) develops from minor to severe disorders.

lower limb ischemia and trophic disorders due to diabetes

Minor microcirculatory disturbances in diabetes are manifested by a creeping sensation, numbness and cooling of the feet, ingrown nails, fungal infection and cracks in the soles of the skin. Severe disorders develop due to the attachment of a secondary bacterial flora due to a decrease in local and general immunity and are manifested by long-term non-healing trophic ulcers. In severe cases, gangrene of the foot develops and amputation of the feet may even be necessary.

We should also mention violations of microcirculation in the vessels of the skin.

microcirculation insufficiency in the skin

The first type is characteristic especially for individuals with vegetative-vascular dystonia of the hypertonic type (when there is a tendency to spasm of large vessels with high blood pressure) and is characterized by spasm of small vessels with malnutrition of the skin cells of the face. As a result of this, a wrinkled type of aging is gradually developing – a network of wrinkles is formed throughout the face, even in the amygym areas. The risk factor for premature aging of this type is smoking.

  • The second type is characteristic of individuals with dystonia by the hypotonic type (a tendency to low blood pressure) and is characterized by the occurrence of micro-edema in the skin of the face, which is externally manifested not by wrinkles, but by the deformation type of skin aging – swelling, spider veins and red spots on the face. The risk factor for premature aging of this type is obesity.
  • The third type of changes in the microcirculation of the skin has signs of both options and is more often observed after 40-45 years.

    Undoubtedly, many disorders of microcirculation are dangerous to the health and even life of the patient, especially if they occur acutely. So, blood flow disorders in the small vessels of the heart muscle that occurred during acute coronary thrombosis lead to severe myocardial ischemia, and after a few minutes or hours – to necrosis (death) of the heart muscle cells – acute myocardial infarction develops. The wider the affected area, the worse the prognosis.

    In acute thrombosis of the femoral arteries and veins, any delay in terms of medication and surgery can lead to loss of limb.

    The same goes for people with diabetic angiopathy and diabetic foot syndrome. Such patients should be trained in the proper care of their feet, so as not to lose their legs with the development of a purulent infection or gangrene of the foot.

    In the case of long-existing processes in the body, for example, with impaired microcirculation in the kidneys and in the brain with hypertension, there is, of course, a violation of the function of the organ, but there is no acute threat to life.

    If you do not take any measures to combat circulatory disorders, then the result of this after a certain period of time will be disfigured with blue nodules and legs twisted with swollen veins. It is also likely to damage the deep internal veins. Unfortunately, pathological changes affecting peripheral vessels are chronic and do not go away without treatment.

    Doctors involved in the treatment of blood vessels, have at their disposal various means of improving blood circulation in the legs. With the help of medications and physiotherapeutic procedures, the pathological condition of the veins and arteries of the lower extremities is reduced or eliminated. If these methods prove ineffective, then they resort to such a radical method as an operation with removal, cauterization or sclerosis of the affected part of the vessel. But such surgery is quite painful, and as a result, the cause of vein deformity is not completely eliminated.

    Herbal Medicines

    These drugs are used to treat circulatory problems of the brain, have a small number of contraindications, and are used for preventive purposes. Some are sold over the counter, drunk according to the instructions.


    Drugs that improve blood circulation in the legs should be prescribed only by a doctor. After questioning and external examination of the patient, he is sent for examination. Based on the results obtained, the doctor prescribes the necessary drugs to normalize blood circulation in the lower extremities. So how to improve blood circulation in the legs? To do this, use the following tools:

    • Angioprotectors. They are needed to improve microcirculation, as well as normalize vascular permeability, due to which normal metabolic activity returns to the walls. These include “Curantil”, “Persanthin”, “Trental”, “Flexital”, “Doxy-Hem”, “Pentoxifylline”, “Radomin”, “Vazonit”.
    • Medications of low molecular weight dextran. Thanks to these drugs, additional blood volume is supplied from the intercellular space into the bloodstream. As a result, blood flow significantly improves. This category includes the following medications: “Reomakrodeks” and “Reopoliglyukin.”
    • Drugs containing prostaglandin Е1 (“Vazaprostan”). Thanks to them, blood flow is improved and microcirculation is normalized. These drugs also contribute to the expansion of blood flow and normalization of blood pressure.
    • Calcium channel blockers that even affect the brain vessels. These include: “Kordafen”, “Kordaflex”, “Adalat”, “Stamlo”, “Norvaks”, “Plendil”, “Foridon”, “Lacipil”.
    • Myotropic antispasmodics. With the help of such medicines, the vessels dilate and the blood begins to circulate freely. In addition, they are well relieve cramps. These medications are “Mydocalm”, “Kavinton”, “Eufillin”, “Halidor”.

    When blood circulation stimulation is needed

    Tinnitus, frequent pain, dizziness usually occur in older people. But in the era of total computerization, this problem became very young. The reason is limited physical mobility.

    The computer operator spends the whole working day in the same position. The cervical muscles are constricted and worsen blood flow, osteochondrosis is exacerbated. The circulation of blood and brain fluid is disturbed, the brain experiences oxygen starvation.

    Professionals know that memory loss can occur after an injury. In old age, dementia occurs. In chronic alcoholics, blood flow in the brain is impaired. Hypertensive patients also suffer from the fact that pressure surges cause sharp vasoconstriction.

    Disruption of metabolism, the deposition of fatty plaques, also lead to negative symptoms:

    • sharp, moving headaches;
    • dizziness;
    • pain in the eyes;
    • nausea;
    • noise in ears;
    • arrhythmia;
    • fainting;
    • feeling short of breath;
    • complete and partial loss of consciousness;
    • cold or burning in the fingers of the limbs;
    • frequent increase in blood pressure;
    • forgetfulness, memory loss.

    The appearance of such phenomena signals that it is necessary to restore blood circulation in the brain.

    Stabilization of the blood circulation of the brain during the development of cervical osteochondrosis is not an easy task. The main problem is that the disease has recently been diagnosed in people at the age of 25. All problems are associated with the constant sitting in front of the computer in an anatomically incorrect position.

    Cervical osteochondrosis causes problems with the main blood vessels in this area, vertebral artery syndrome appears. In this situation, drugs to stimulate blood supply will not be enough. In this situation, other measures of influence on this part of the spine are required. Doctors advise wearing a Shants collar in everyday life, performing simple exercises that stimulate blood flow.

    • Lower your head so that the chin is in contact with the neck, then make turns in different directions 5 times.
    • Raise your head slightly, perform similar turns 5 times in each direction.
    • Make head tilts so that the ear touches the shoulder 5 times on each s >

    How to improve blood circulation in the legs? For these purposes, use other drugs.

    Bioflavonoids increase the elasticity of red blood cells, which improves blood flow. Ganglion blockers dilate venules, arterioles, and small veins and evenly distribute blood volume in the lower extremities. Such drugs include Dimekolin, Camphonium, Pakhikarpin, Temekhin, Pirilen.

    Also this problem is solved by such drugs as alpha-blockers. They have a complex effect on the entire body, expanding blood vessels not only in the lower extremities, but also in the internal organs.

    Traditional medicine

    Vascular pathology of the legs is not an independent disease. This is one of the signs of a poor body condition. If in the last century only elderly people worried about joints and blood vessels, now young people are already worried about them. In women, such lesions on the legs occur after childbirth.

    In the early stages, these diseases do not manifest themselves in any way, so it is important to engage in prevention and eat only healthy foods, do simple exercises to improve the general condition and improve blood circulation in the vessels of the feet and calves. There are also effective alternative methods for cleansing blood vessels at home. Let us describe some of them:

    1. Strengthening blood vessels with cranberries. It is necessary to take half a kilogram of fresh red beets, cranberries, black radish and 0,5 liters of alcohol. Grind these products and put in a glass three-liter jar. Then pour alcohol, cover and leave to infuse in a dark and cool room. After 15 days, strain, pour into a clean jar and store in the refrigerator. Drink 30 ml per day half an hour before breakfast.
    2. Treatment of varicose veins with Kalanchoe leaves. Grind them, put them in a jar of 0,5 l, the leaves should fill it in half. Pour water and insist in a dark place for 7 days. Shake the jar once a day. Strain the infusion and rub its feet overnight (starting from the foot to the hips). The course of treatment is 1 month.
    3. Blueberry limb rejuvenation. Grind the berries. Apply the resulting slurry to the legs for 1 hour. After rinse with water.
    4. Cleaning the vessels with lemon and garlic. This tool will not only help cleanse the circulatory system, but also lower cholesterol and relieve headaches. Grind 4 lemons and 4 heads of garlic. Stir and pour 2,5 liters of cold boiled water. Leave for 3 days in a jar with a lid. The treatment is long, but effective (from September 1 to May 30). Take 100 g in the middle of the day.

    Well-known drugs for relieving cerebrovascular spasms are found in every home medicine cabinet. This is a spazmalgol, analgin, which we swallow quickly when our head hurts. However, you should be aware that the causes of headaches can be not only in cramps and a different medicine may be needed.

    How to improve blood circulation in the legs? Folk remedies can help solve this problem only if the disease has a mild degree. In more serious cases, you need the help of a doctor.

    The greatest effect bring alcoholic tinctures of flowers of lilac or chestnut. To do this, the flowers are placed in a half-liter jar, almost to the top filling it, and pour vodka or alcohol, diluted by half. The jar is closed with a plastic lid and placed in a dark place for two weeks. During this time, the liquid acquires a dark brown color. It should be filtered, then rubbed her inner thighs and below.

    For these purposes also use chestnut fruit, which is pre-flatten. Preparation and use of tincture is carried out in the same way.

    How to improve blood circulation in the legs of the elderly? All of the above methods are effective for people of all ages.


    Vascular drugs help improve blood circulation in the brain, thanks to a strengthening and tonic effect. The body is freed from the effects of toxins. The list includes herbal medicines, the use of which the heart does not deteriorate. We list the main ones:

    • Ginkgo bilboa – eliminates spasms, stimulates microcirculation, eliminates puffiness, stabilizes pressure inside the skull.
    • Medications with a small periwinkle belong to the category of antispasmodics, prevent the formation of blood clots, stimulate blood flow. The doctor is authorized to prescribe such funds to people, they are not used for self-treatment because of the strong effect and several contraindications.


    Blood clotting blood clots prevent blockage. Their use stimulates capillary microcirculation.

    These drugs include:

    • Angioprotectors are created in the form of dragees, tablets, solutions for infusion.
    • Preparations for internal input: Anginal, Apricor, Parsedil.

    Antiplatelet agents prevent the accumulation of platelets, which contribute to blockage of capillaries. Under the influence of such drugs, microcirculation is stimulated, vascular patency increases. The drugs have the properties of angioprotectors, reduce vascular fragility, due to the stimulation of metabolic processes in the walls.

    Nicotinic Ac >

    Among the potent drugs to stimulate blood circulation are drugs from nicotinic acid. The drugs do not affect large vessels, contribute to the expansion of capillaries, strengthen the walls, lower cholesterol.

    It is necessary to use only on the recommendation of a specialist and under his supervision so that complications and side effects do not occur. Consider several popular drugs: Enduratin, Nikoshpan, Adipimox.

    Blood circulation medications

    The state of thin vessels helps to regulate such funds, health improves, dizziness stops, gait ceases to be shaky, signs of acute and chronic pathologies stop. The duration of the course of use is determined by the specialist, taking into account the severity of the disease. We list the main assets: Betaserk, Vestibo, Tagista.

    Betagistin belongs to this category of drugs, it corrects blood flow in the capillaries, helps to cope with dizziness attacks, eliminates the unsteadiness of gait in chronic disorders. Tablets of 8 and 16 mg are taken in courses.

    The dosage is determined by the attending physician, divided into 3 doses per day. Medications are not prescribed for pregnant and lactating, carefully used for bronchial asthma, ulcerative formations.

    Nootropic drugs are used to improve memory, promote metabolism in the formed elements of the brain. Thus, the activity of thinking is stimulated, information is better absorbed.

    Similar drugs are used in the fight against vascular dementia in elderly citizens with encephalopathy or damage to brain vessels. It is pointless for young healthy patients to take these pills. Under the influence of nootropics, it is possible to transfer neurocyte membranes to a stable state, to improve the resistance of brain tissue to oxygen deficiency.

    2) Preparations of prostaglandin E1 – drugs of this group have a positive effect on microcirculation and blood flow, and also have a hypotensive effect: vazaprostan

    3) Calcium channel blockers are mainly used to improve blood circulation in the brain. Contribute to the improvement of vascular microcirculation and limit damage to brain tissue. These include:

    • cinnarizine
    • logimax
    • shit
    • nimotope
    • cinnasan
    • brainal
    • norvax
    • arifon
    • cordipin
    • foridon
    • nifekard
    • kordafen

    4) Low molecular weight dextran preparations – drugs of this group positively affect blood flow due to the attraction of additional blood volumes from the intercellular space. These include:

    • reomacrodex
    • hemostabil
    • reopoliglyukin

    10) Dopamine receptor stimulants – this group of drugs has an effect on dopamine receptors, which, in turn, leads to vasodilation. Improve blood circulation in the lower extremities – pronoran.

    All materials are published under authorship, or by the editors of professional physicians (about the authors), but are not a prescription for treatment. Address to experts!

    Is it possible to somehow improve or restore blood flow in the smallest vessels of the body? The answer to this is yes, at the current stage of the development of medicine there are enough funds that can regulate vascular tone, as well as affect their inner wall and the ability of blood to thrombus, and, thus, contribute to the improvement of microcirculation.

    To improve blood circulation in the lower extremities, the following groups of drugs are generally used to improve microcirculation:

    1. Antispasmodics (papaverine, spasmalgon) – remove the tone of large and small vessels due to the effect on the smooth muscle layer in their wall,
    2. Angioprotectors and disaggregants (pentoxifylline (vasonite), trental, chimes) contribute to the improvement of metabolic processes in the vascular wall itself, due to which its permeability to the liquid part of the blood is stabilized,
    3. Biogenic stimulants (solcoseryl, actovegin) have a similar effect as protectors,
    4. Vasodilators (nifedipine, amlodipine) also weaken the vascular tone.
    5. In acute conditions, drugs are used that reduce blood coagulation and prevent further thrombosis – anticoagulants (heparin, warfarin), antiplatelet agents (aspirin), fibrinolytics (urokinase, streptokinase, alteplase).

    It is possible to improve microcirculation in the brain using the same drugs, but the following are more often used – antispasmodics (drotaverin), vasodilators (cinnarizine, vinpocetine), antiplatelet agents (trental, chimes), microcirculation correctors (betagistin), and nootropic drugs (piracetam, butot ), polypeptides (cortexin, cerebrolysin), preparations of gamma-aminobutyric acid (pantogam, phenibut).

    In addition to these drugs, antioxidants and antihypoxants (mexidol, preductal) are highly effective as microcirculatory correctors for the heart muscle, which not only improve blood flow in the myocardial capillaries, but also increase the resistance of its cells to oxygen starvation (hypoxia).

    Of the means to correct microcirculation disorders in the kidneys, pentoxifylline, trental and chimes are more often prescribed.

    In conclusion, it should be noted that blood flow disorders in small vessels are a rather extensive concept, containing a large number of diseases as causative factors. Therefore, only a full-time doctor should look for these factors, and patients who have some of the above symptoms should seek the help of specialists.

    • radomin
    • quarantine
    • pentoxifylline
    • trental
    • flowerpot
    • phentolamine
    • prazosin
    • sermion
    • pyrene
    • temekhin
    • dimecoline
    • pachycarpin

    10) Dopamine receptor stimulants – this group of drugs has an effect on dopamine receptors, which, in turn, leads to vasodilation. Improve blood circulation in the lower extremities – pronoran.



    The mechanism of violations may be different. Therefore, do not self-medicate, drink pills that helped a neighbor. It is dangerous to buy drugs to expand the vessels of the brain without the control of a doctor. So you can worsen the condition.

    Improves metabolism in the brain, impaired by cervical osteochondrosis, one drug, and impaired blood flow with vascular sclerosis – treats a completely different one.

    Medications for the treatment of cerebral vessels have a different mechanism of action. To find out the exact cause of the deterioration of the state of the vessels, it is necessary to undergo a general and detailed examination. Without a specialist, one cannot understand the wide variety of medications.

    A physician will prescribe exactly the drug that is suitable for solving a specific problem, discovered by the results of tests and examinations. In addition, the doctor knows which modern remedy will act faster and better in this particular case.

    The effects that various drugs have:

    • generation and amplification of impulses sent by the brain;
    • improved blood circulation;
    • acceleration of metabolic processes;
    • normalization of glucose uptake;
    • free radical blocking;
    • restoration of blood vessels after strokes and injuries.

    In the same medicine, it is not yet possible to combine all these actions. The modern pharmaceutical industry has not yet gone so far. Some memory-improving pills are prescribed even for very young patients. They are sold without a prescription, they are used to relieve stress, restore sleep and working capacity, improve academic performance at school.

    Patients who are already over 70 should take into account nootropic drugs. They contribute to the saturation of the cell structure with blood and oxygen, contribute to better absorption of glucose. Efficiency, focus and memory are enhanced by increasing sugar levels.

    The disadvantages of nootropics include addiction and the need to increase dosage. To prevent this from happening, experts advise taking small breaks in use and replacing drugs. For preventive purposes, in addition to nootropics, the following are acceptable for use:

    • Vitamin complex, remedies with ginseng extract.
    • Glycine helps get rid of the effects of scleosis, improves intellectual activity.
    • Piracetam stimulates the blood circulation, metabolism.
    • Tanakan improves intellectual activity, helps get rid of anxiety.


    To strengthen the vessels, patients are often prescribed injections. In this way, the active components of the drugs enter the blood faster, tone the walls of the capillaries, give the maximum effect.

    Injectable drugs are classified as follows:

    • Neutron drugs improve the functioning of nerve tissues.
    • Myotropic, improve muscle fibers.
    • Combined action.
    • Alkaloids-based drugs eliminate vasospasm, widen the lumen, increase metabolism, and help get rid of blood clots.
    • Medicines based on nicotinic acid act on the capillaries, help eliminate cholesterol plaques.
    • Vasodilating.


    These tools help to expand the diameter of the vessels, relax the smooth muscle tissue of the capillaries. Such funds do not cause danger, act softly. They are used as pills for stimulating blood circulation and injections that belong to this group.

    Such drugs do not effectively affect the vessels under the influence of atherosclerosis. They contribute to the redistribution of blood circulation, activating in healthy areas in which the blood vessels are better preserved. Therefore, problem areas of the brain are not adequately supplied with blood.

    Alpha blockers

    If vascular agents are used to stabilize blood circulation in the brain from such a subgroup, blood vessels can expand without damage to blood circulation. Such funds are used for cervical osteochondrosis. Often there is a stabilization of microcirculation.

    Drugs in this group have a side effect, significantly lower blood pressure. Medicines are used only as directed by a doctor in the indicated dosage.

    Alpha-adenoblocker drugs not only contribute to the expansion of capillaries, but also improve the metabolic process in the brain tissues, contribute to better platelet aggregation.

    Detonic – a unique medicine that helps fight hypertension at all stages of its development.

    Detonic for pressure normalization

    The complex effect of plant components of the drug Detonic on the walls of blood vessels and the autonomic nervous system contribute to a rapid decrease in blood pressure. In addition, this drug prevents the development of atherosclerosis, thanks to the unique components that are involved in the synthesis of lecithin, an amino acid that regulates cholesterol metabolism and prevents the formation of atherosclerotic plaques.

    Detonic not addictive and withdrawal syndrome, since all components of the product are natural.

    Detailed information about Detonic is located on the manufacturer’s page www.detonicnd.com.

  • Svetlana Borszavich

    General practitioner, cardiologist, with active work in therapy, gastroenterology, cardiology, rheumatology, immunology with allergology.
    Fluent in general clinical methods for the diagnosis and treatment of heart disease, as well as electrocardiography, echocardiography, monitoring of cholera on an ECG and daily monitoring of blood pressure.
    The treatment complex developed by the author significantly helps with cerebrovascular injuries and metabolic disorders in the brain and vascular diseases: hypertension and complications caused by diabetes.
    The author is a member of the European Society of Therapists, a regular participant in scientific conferences and congresses in the field of cardiology and general medicine. She has repeatedly participated in a research program at a private university in Japan in the field of reconstructive medicine.