Hypertension pills list of the best drugs of the new generation

Do not self-medicate if you have high blood pressure. To choose the right pill for hypertension, it is important to consult a doctor. He will find out what pressure you have now, what indicators you need to achieve after treatment. This is especially important for older people – properly selected antihypertensive drugs prolong life, improve its quality.

Modern methods of treating hypertension are aimed at lowering and normalizing blood pressure. Only a qualified doctor is able to correctly select, from the whole variety, the necessary drugs, taking into account the analyzes, the patient’s age. At the time of admission, he:

  • learns about concomitant diseases;
  • determines contraindications;
  • empirically selects drugs for pressure;
  • prescribe a dosage starting with small values;
  • determine the regimen, depending on the duration of action of the drugs;
  • will monitor the effectiveness of treatment.

Modern drugs for lowering blood pressure are different in that they have few side effects. The pharmaceutical industry offers the latest developments that have received excellent reviews from doctors. In the list of a new generation of tablets for hypertension there are combined preparations that have both a vasodilating, diuretic and antispasmodic effect: “Andipal”, “Twinsta”.

Modern pills for hypertension – the latest in the market of pharmacological medications – require the mandatory supervision of a doctor. In each group of drugs there are innovations:

  • calcium antagonists – “Amlodipine”, “Riodipine”;
  • sartans – “Valsartan”, “Cardosal”;
  • diuretics – “Torasimide”, “Rolofilin”;
  • alpha and beta blockers – Nebivolol, Carvedilol;
  • ACE inhibitors – Enalapril, Lizinoproil and its analogue – Dapril.

When using medications to treat hypertension, many doctors advise using the combined method of therapy, since it is such treatment that is considered the most effective. The essence of the method is the use of several drugs at once, which belong to different groups.

This combination of drugs will improve well-being within a week. Also, in the treatment of pathology, you can take diuretics with inhibitors, which will complement the actions of each other.

It is recommended that you familiarize yourself with what people drink to eliminate the symptoms of hypertension. Among the huge number of drugs for hypertension, several of the most effective drugs stand out. The list of drugs that should be drunk with a decrease in blood pressure includes six drugs.

Detonic – a unique medicine that helps fight hypertension at all stages of its development.
Detonic for pressure normalization

The complex effect of plant components of the drug Detonic on the walls of blood vessels and the autonomic nervous system contribute to a rapid decrease in blood pressure. In addition, this drug prevents the development of atherosclerosis, thanks to the unique components that are involved in the synthesis of lecithin, an amino acid that regulates cholesterol metabolism and prevents the formation of atherosclerotic plaques.

Detonic not addictive and withdrawal syndrome, since all components of the product are natural.
Detailed information about Detonic is located on the manufacturer’s page www.detonicnd.com.


This drug is part of the sartans group to lower blood pressure. The use of “Losartan” prevents the narrowing of blood vessels, which improves blood flow. The effectiveness of the drug is due to angiotensin, which is part of it.

To get rid of the manifestations of hypertension, you need to drink a tablet of “Losartan” every day. The patient’s well-being is completely normalized a week after the start of drug therapy.


This is a fairly effective ACE inhibitor, characterized by almost instant action. The pressure drops 2-3 hours after taking the tablets.

To improve the effectiveness of “Lisinopril”, it is necessary to determine the optimal dosage. To do this, you should visit a doctor who will deal with the diagnosis of pathology and on the basis of the results obtained will determine the daily dose and duration of treatment. On average, “Lisinopril” drink at least ten days.

“Renipril GT”

This tool is popular among people who drink combination medications in the treatment of high blood pressure. “Renipril GT” is made from hydrochlorothiazide and maleate. These components have a hypotensive effect on the body, improve vascular patency and reduce blood pressure.

“Renipril GT” is used only in the treatment of adults, since the drug is contraindicated for hypertensive patients under 16 years of age. To get rid of high blood pressure, you will have to drink two tablets of Renipril daily.


Among all ACE inhibitors, it is Captopril that is most popular. This medicine is often used in first aid during exacerbation of symptoms of hypertension. “Captopril” is not suitable for long-term use, since frequent use of tablets may result in lowering blood pressure to critical values. To prevent side effects, it is better to drink the medicine under the supervision of a doctor.

Tablets are made from indapamide, which has a diuretic and vasodilator effect. Regular use of “Arifon” helps to remove excess fluid from the body and reduce high blood pressure. Before using the tablets, you need to familiarize yourself with their contraindications. “Arifon” should not be used in patients with impaired liver and kidney function. Also, pregnant girls and adolescents will have to refuse to take pills.


Another diuretic that reduces blood pressure is Veroshpiron. The tool helps to preserve potassium in the body, which is responsible for the work of the cardiovascular system. “Veroshpiron” is drunk only with combination therapy along with other medicines. So that when using tablets, side effects do not appear, you need to consult a specialist and determine the optimal dosage.

There are several medications that people often use for hypertension. However, this should not be done, since these funds do not help to improve well-being.


Tablets are used in the treatment of inflammation and for pain relief. “Analgin” does not affect the vessels, and therefore it does not help hypertensive patients.


It may be useful only in the initial stages of pathology. In the treatment of hypertension with complications does not lower elevated blood pressure.

These drugs help only with the complex treatment of the disease. Together with them sedative or diuretic tablets are well combined.


This drug is contraindicated in hypertensive patients, since with high blood pressure it can provoke complications. Doctors recommend drinking Citramon to hypotensive patients who need to increase blood pressure.

Throughout the civilized world, six different groups of drugs that lower blood pressure are used. Let’s say right away that understanding their features for a person who is not knowledgeable in medicine is not so simple, but Russian consumers are ready to penetrate deeply into pharmacological details and carefully study the instructions for the drugs , if desired, and good serve, they can definitely cope with this task.

  • Low blood pressure is 100-110 / 70-60 mm Hg
  • The most optimal pressure is considered to be 120/80 mm Hg.
  • Slightly elevated is called Blood pressure 130-139 / 85-89 mm Hg.
  • High pressure is considered a value of more than 140/90 mm Hg.

Since age causes various changes in the human body, they should be taken into account when measuring pressure. Children and adolescents can often have low blood pressure, while the elderly are characterized by a higher value.

  • Diuretics and sartans. Combinations of the following drugs: gizaar (losartan-hypothiazide), ataxand plus (candesartan-hypothiazide), mycardis plus (telmisartan-hypothiazide), coaproval (Iprosartan-hypothiazide).
  • Diuretics and ACE inhibitors. Combinations of drugs of these groups – ramipril-hypothiazide (Amprilan, Hartil), lisinopril-hypothiazide (Iruzide), enalapril-indapamide (Enzix), enalapril-hypothiazide (Enap NL, berlipril plus), captopril-hypothiazide (capozidl-apidoprind) noliprel).
  • Diuretics and beta blockers. The combination of bisoprolol with hypothiazide (bisangil) is used to minimize the risk of cardiovascular complications.
  • Ca-channel blockers together with angiotensin-converting enzyme inhibitors. This combination can also be used for the treatment of resistant forms of hypertension, since when using these drugs, the body’s sensitivity to medications does not decrease. It includes the following combinations: amlodipine with perindopril, trandolapril with verapamil.
  • Calcium channel blockers with sartans. Combinations of the following drugs: telmisartan with amlodipine, losartan with amlodipine.
  • Diuretics with calcium channel blockers. The most popular combination is chlortalidone and atenolol.

    Hypertension requires a systematic approach to therapy. The disease is dangerous for its complications, the most serious of them are heart attack and stroke. At the initial stages of the disease, it is possible to improve the condition by adjusting the lifestyle and diet, increasing physical activity. At more advanced stages of the disease, drugs can not be dispensed with. Drugs for pressure of a new generation, a list of which will be presented below, practically do not cause side effects.

  • Renin inhibitors.
  • Angiotensin Receptor Antagonists 2.
  • Diuretics.
  • ACE inhibitors.
  • Alpha and beta blockers.
  • Calcium channel blockers.

    Compared to its predecessors, the latest generation of blood pressure medicines have several advantages: they lower blood cholesterol, prevent the occurrence of dangerous complications, and normalize blood pressure.

    New generation drugs for hypertension not only reduce the risk of developing unpleasant symptoms, but also improve the quality of life of patients

  • Improve the condition of the patient with minimal negative consequences.
  • They have a longer effect. They improve blood pressure by eliminating triggers.
  • Well tolerated by elderly patients.
  • Do not cause mental depression, have a sedative effect.
  • Do not reduce physical activity and libido.
  • Improve secretory function of the kidneys.

    Groups of tablets for high blood pressure

    Pills to lower the pressure to the patient are selected by the attending physician, taking into account his condition. There are several groups of drugs that can regulate blood pressure. All of them act in different ways, have their own characteristics, contraindications, side effects. Tablets should be drunk constantly, regardless of the tonometer.

    Drugs that can regulate pressure solve the main problems:

    • reduce headache;
    • prevent nosebleeds;
    • flies are removed before the eyes;
    • prevent renal failure;
    • reduce heart pain;
    • prevent the risk of stroke, heart attack.

    Take a closer look with these drugs. The main groups of drugs that solve the problems of high blood pressure:

    • beta-blockers;
    • alpha blockers;
    • calcium antagonists;
    • angiotensin 2 antagonists;
    • diuretics;
    • ACE inhibitors.

    Beta blockers

    Alpha blockers

    Tablets of this group have antispasmodic action, dilate blood vessels, relaxing muscles along them. This helps to reduce pressure. If you take drugs separately from diuretics, beta-blockers, swelling and headaches are possible. Alpha blockers are used in severe cases when other drugs are powerless. Pills are addictive, capable of provoking heart palpitations, hyper-hairiness. These drugs include: “Hydralazine”, “Minoxidil.”

    Calcium antagonists

    This group of drugs has a different name – calcium channel blockers. Tablets interfere with the entry of calcium into the cells of blood vessels, which expand when this occurs, and a decrease in pressure occurs. The head of the drug rating is Nifedipine, which can quickly remove the hypertensive crisis. With high blood pressure, which is accompanied by diseases – arrhythmia, diabetes mellitus, kidney disease, appoint Verapamil, Amlodipine. These drugs do not cause inhibition, help transfer physical activity. Often prescribed to older people.

    To modern group drugs that have minimal side effects, another name is used – sartans. The effect of use is enhanced when combined with diuretics. Stable application results are visible after a few weeks. Popular tablets of this group: “Lozap”, “Valz”, “Lozartan.” They are not addictive, have a long action – you need to take them once a day. Due to their use:

    • reduced risk of stroke, heart attack;
    • the probability of renal failure decreases.

    Among the tablets for hypertension, diuretics are prescribed as one of the first drugs. They help remove excess water and salt from the body, and reduce swelling. This reduces the amount of blood, less stress on the heart. All this contributes to the normalization of pressure. Diuretics are prescribed only by a doctor – this is due to the fact that they remove calcium, potassium and magnesium from the body. They have contraindications for use. Together with diuretics, drugs are prescribed that restore the balance of potassium, calcium and magnesium.

    Effective diuretics with high blood pressure:

    • “Furosemide”, “Diuver” – potent drugs that actively remove calcium and magnesium, are not recommended during pregnancy.
    • “Hypotheazide”, “Indapamide” – act slowly, have few side effects.
    • “Veroshpiron” – has a weak diuretic effect, but is a potassium-sparing drug, helps with the highest, third degree of arterial hypertension.

    It is worthwhile to be careful about diuretics for hypertension. They sell them without prescriptions, drugs are cheap, but you need to drink them only as directed and under the supervision of a doctor. This is due to side effects:

    • the risk of diabetes is increased;
    • cholesterol rises;
    • problems with potency appear;
    • fatigue becomes higher;
    • hormonal disruptions occur;
    • possible loss of consciousness.

    Such drugs are prescribed for patients with hypertension, in whom heart failure and diabetes mellitus have been identified, and there is coronary heart disease. ACE inhibitors dilate blood vessels, contribute to low blood pressure readings. They reduce the risk of stroke, heart attack, protect the kidneys, reduce the likelihood of developing diabetes. The drugs have a short duration of action, so they are taken according to the scheme prescribed by the doctor.

    These drugs have few side effects. Sometimes a dry cough appears, small swelling of the face. They should be taken at the dose indicated in the instructions, because of the possibility of a sharp decrease in pressure. Prescribe drugs along with diuretics, calcium antagonists – with this option, a strong therapeutic effect is obtained. Often used ACE inhibitors:

    READ  Sinus bradycardia of the heart, what is it in adults, ICD-10 code, types

    There are several groups of medications for the hypotensive spectrum of effects that are prescribed in a complex or separate manner during therapy for arterial hypertension:

    • diuretic drugs (diuretic);
    • Beta blockers;
    • Alpha blockers;
    • ACE inhibitors;
    • calcium channel blockers (BCC);
    • angiotensin 2 receptor blockers (ARBs);
    • sympatholytics;
    • central antagonists;
    • direct renin inhibitors;
    • ganglion blockers;
    • vasodilators.

    Ganglion blockers reduce the sensitivity of nerve nodes. Among them, the following have a positive effect in hypertension: They slow down the transmission of signals of the nervous system of sympatholytics. Among them, cardiologists with hypertension recommend taking the following: Direct renin inhibitors have a vasodilating effect. Of these, only Tecturna is prescribed for arterial hypertension.

    Any drug, even if it is without side effects, can provoke an allergy due to individual intolerance to the components, so before the start of the course, it is better to undergo an examination and combine the drugs under the guidance of a doctor, especially for pregnant women or in the presence of concomitant pathologies.

    Rapid Action High Pressure Tablets

    Factors that can increase the risk of death in people with hypertension:

    • history of stroke or cerebral ischemia;
    • heart failure, coronary heart disease, myocardial infarction;
    • renal failure, diabetic nephropathy;
    • the presence of signs of damage to peripheral vessels, exfoliating an aortic aneurysm;
    • changes in the retina – exudates, hemorrhages, swelling of the optic nerve papilla.

    However, the highest risk of death is observed in patients who have four manifestations at once: However, many people cannot assess the risks of hypertension correctly and adequately, believing that high blood pressure is not scary, and you can even bring it down without pills There are several categories of patients with hypertension.

    The former ignore the danger of blood pressure risks and try to live in a measure of the endurance of their health. Thus, believing that if the disease does not cause significant discomfort, then you can do without blocking the jumps in blood pressure tablets. The second patients, on the contrary, overestimate the risk and try to heal the disease with all the drugs that come to hand, not paying attention to side effects, but ignore trips to the doctor.

    The drugs have a long therapeutic effect, which is convenient in the treatment of hypertension. It is enough to take only 1-2 tablets per day to normalize the pressure at home and achieve stable remission. List of long-acting drugs of the new generation:

    • Metoprolol – 29.00 rub.
    • Diroton – 108.00 rub.
    • Losartan – 109.00 rub.
    • Cordaflex – 91.00 rub.
    • Prestarium – 366.00 rub.
    • Bisoprolol – 31.00 rub.
    • Propranolol – 182.10 rubles.

    These funds are used for long-term combination therapy for hypertension of the 2nd to 3rd degree. Features of the reception are a long-term cumulative effect. To obtain a lasting result, you need to take these drugs for 3 weeks or more, so you do not need to stop taking it if the pressure has not decreased immediately.

    List of quick-acting antihypertensive drugs: At high pressure, it is enough to put a half or a whole tablet of Captopril or Adelfan under the tongue and dissolve. Pressure drops in 10-30 minutes. But you should know that the effect of taking such funds is short-lived. For example, a captopril patient is forced to take up to 3 times a day, which is not always convenient.

    Pills for high blood pressure, which are characterized by the onset of a rapid hypotensive effect, are a first aid for hypertension. The list of drugs with this effect includes: These drugs should be available to hypertensive patients at any time, as they can prevent the negative consequences of a sharp increase in blood pressure, quickly lowering them to an acceptable level.

    Side effects of the drugs and restrictions on their use are directly dependent on the category of a particular medication, as well as on its main active ingredient. However, there are some general contraindications:

    • period of gestation;
    • severe liver pathology;
    • impaired kidney function;
    • the period of breastfeeding;
    • obstructive processes of bile ducts;
    • bronchial asthma;
    • the patient’s age is less than 18 years;
    • decompensated heart failure.

    It is quite difficult to choose a medication that would not have negative effects when used in a particular case. Any of the drugs can potentially cause negative reactions from the body and lead to serious health problems. The most common side effects when taking antihypertensive drugs are as follows:

    • nausea and vomiting;
    • soreness of the digestive system;
    • allergic reactions;
    • a rapid drop in blood pressure;
    • dry mouth;
    • impaired stool;
    • depressive conditions;
    • sleep disturbances.

    If such reactions occur on the part of the body, it is required to refuse to take the medication and report the side effects to the attending physician. He will be able to adjust drug therapy based on the circumstances.

    Lisinopril is presented as a 3-generation ACE inhibitor with a diuretic effect. Thanks to the new composition, the drug is prescribed for diabetes. Also, the medicine is safe for elderly patients.

    This is not about completely new tablets, they are all the same diuretics, ACE inhibitors or calcium antagonists. The difference is only in fewer side effects and contraindications compared to previous generations.

    Resorption of a whole tablet of Adelfan or Captopril under the tongue will balance the pressure on average after 15 minutes. The considered drugs do not last long, this is their main drawback.

    To stabilize heart rate and pressure at home, you should drink long-acting tablets. One or two tablets per day of the following drugs is enough, and you can achieve a stable remission:

    The therapeutic effect is prolonged, they are usually used in the combined treatment of hypertension. Hypertensive patients are shown maintenance therapy until the end of their life, so taking a pill twice or twice a day is very convenient. The effect of taking drugs with a prolonged effect lasts for up to 24 hours.

    Active ingredientsTrade names
    Thiazide ACE inhibitors
    Hydrochlorothiazide lisinopril
    • Iruside;
    • Lysoretic;
    • Lister.
    Hydrochlorothiazide enalapril
    • Burlipril plus;
    • Renipril GT;
    • Enap-HL.
    Hydrochlorothiazide ramipril
    Indapamide Enalapril
    Hydrochlorothiazide captopril
    Thiazide sartan
    Hydrochlorothiazide losartan
    Hydrochlorothiazide telmisartan
    Thiazide beta blocker
    Chlortalidone atenolol
    • Tenoretic;
    • Tenorm;
    • Tenoric.
    Hydrochlorothiazide metoprolol
    Hydrochlorothiazide propranolol
    Thiazide calcium antagonist
    Hydrochlorothiazide amlodipine
    Amlodipine indapamide
    Sartan Calcium Antagonist
    Valsartan amlodipine
    • Artinov AM;
    • Vamloset;
    • Diotensin;
    • Exforge.
    Irbesartan Amlodipine
    Losartan amlodipine
    • Amzaar;
    • Amlothop Forte;
    • Lozap AM;
    • Lortenza.
    ACE inhibitor calcium antagonist
    Benazepril Amlodipine
    Lisinopril amlodipine
    • De Creese;
    • Tennis
    • Equacard.
    Thrandolapril Verapamil ER
    Enalapril felodipine
    Beta blocker calcium antagonist
    Bisoprolol amlodipine
    Metoprolol felodipine

    Like any medication, pressure medications have a number of side effects that can appear after they are used to treat the symptoms of hypertension. Common complications include:

    • Frequent urination. The problem appears 2-3 hours after applying the medicine.
    • The broken rhythm of the heartbeat. Some patients complain of arrhythmias due to drug therapy. To establish the causes of problems with the heartbeat, it is necessary to donate blood for analysis.
    • Muscle weakness, accompanied by cramping. A side effect appears if during treatment to use funds that include a lot of potassium.
    • General weakness with dizziness and fainting. Pre-syncope conditions may bother the patient with increased physical activity during therapy.
    • Dehydration. If signs of dehydration appear, you should immediately visit a doctor.
    • Temperature rise. After using medications that are contraindicated to the patient, body temperature may increase, accompanied by severe cough and sore throat.
    • Rash. Redness or a rash on the surface of the skin occurs in people who are allergic to the components that make up the medication.

    All of these side effects are not considered deadly and do not increase the risk of patient death. However, despite this, it is better to consult a doctor before starting medication so that he prescribes the most suitable drugs without side effects.

    How to relieve pressure if it suddenly rose sharply? For urgent relief of a hypertensive crisis, it is necessary to dissolve the Nifedipine tablet under the tongue. Quickly normalizes the pressure reception “Kapoten”. It is also placed under the tongue – until dissolved – the action begins after 10 minutes. It is very important that the decrease in pressure does not occur very sharply – otherwise there may be a stroke.

    The peculiarity of taking pills for hypertension is that they do not cure the cause of the disease, they only lower the pressure and maintain it within the necessary limits. To do this, you need to take drugs constantly, regardless of what the tonometer indicators are at the moment. Unfortunately, drugs have side effects that, with this pattern of use, accumulate in the body.

    More about this, and about contraindications, can be found in the description of each drug. Doctors know about them. Side effects of drugs on the body appear in different ways, and cause from:

    • nervous system – dizziness, weakness, headache;
    • cardiovascular – fainting, heart rhythm disturbance;
    • sensory organs – blurred vision, tinnitus;
    • digestive system – nausea, diarrhea;
    • respiratory organs – cough and bronchospasm;
    • urinary system – acute renal failure.

    Learn more about how to choose a tablet to relieve pressure.

    Do not self-medicate

    Today, drugs for the treatment of hypertension are available from many pharmaceutical companies. They are divided into large groups depending on the action and chemical composition. Prescribing drugs for hypertension should be performed by the attending physician after examination and concomitant examination. Elevated blood pressure can be treated in different ways and the choice of remedy depends largely on the individual characteristics of the patient. Which drugs are suitable in this case can be found based on the experience of the doctor and the patient’s reaction to the tablets.

    What drugs are prescribed?

    The table provides a general list of drugs from various pharmacological groups prescribed for high blood pressure: These drugs are indicated for the treatment of arterial hypertension (persistent high blood pressure) of any degree. The stage of the disease, age, the presence of concomitant diseases, the individual characteristics of the body are taken into account when choosing a remedy, dosage selection, frequency of administration and combination of drugs.

    Tablets from the sartans group are today considered the most promising and effective in the treatment of hypertension. Their therapeutic effect is due to the blocking of receptors for angiotensin II, a powerful vasoconstrictor that causes a steady and rapid increase in A / D in the body. Pills with long-term use give a good therapeutic effect without the development of any undesirable consequences and withdrawal syndrome.

    Treatment of resistant hypertension

    • The first choice drugs for high blood pressure in the elderly are diuretics: hypothiazide or indapamide (for diabetes). The low cost and high efficiency of this group of drugs allows them to be used for single-component therapy for mild hypertension. They are also preferred for volume-dependent hypertension in women during the menopause.
    • The second row is the calcium channel blockers of the dihydropyridine series (amlodipine, nifedipine), which are indicated for atherosclerosis and diabetes mellitus against the background of weight problems.
    • Third place – in lisinopril and sartans.

    Combined drugs: Prestanz (Amlodipine Perindopril), Tarka (Verapamil Trandolapril).

  • Betablockers, dihydroperidine calcium channel blockers, ACE inhibitors;
  • Blockers of beta receptors, calcium channels and sartan;
  • Diuretics, angiotensin-converting enzyme inhibitors, Ca-channel blockers.
  • A third regimen combining the use of diuretics and Ca-channel blockers together with ACE inhibitors is considered the best treatment for resistant hypertension. A combination of spironolactone and thiazide diuretics is also used for these purposes.

    Due to the existence of a huge list of drugs and medication regimens for treating arterial hypertension with medicines that are used for various forms of the disease and are prescribed individually, self-medication can be not only ineffective, but also dangerous to health. Timely access to a doctor minimizes the risk of stroke, heart attack (causes and symptoms of myocardial infarction) and other complications of the disease.

    The first group includes diuretics – Indapamide or Hypothiazide, which are especially relevant among women in menopause or among patients with diabetes mellitus. With mild therapy, single-component therapy with such drugs is allowed.

    It is also possible to take combined preparations: Tark, in which Trandolapril and Verapamil or Prestans are combined, whose action is based on Perindopril and Amlodipine tablets.

    READ  First Aid for Hypertension at Home Standards

    Ca-channel blockers with ACE inhibitors and diuretics. This combination is most effective, as is the combination of thiazide diuretics with spironolactone.

    Self-medication in this situation is not just not recommended, but can lead to a heart attack or stroke when selecting the wrong medication.

    Pressure reduction without medication. Treatment of hypertension without pills

    Attention! The information presented in the article is for guidance only. Materials of the article do not call for independent treatment. Only a qualified doctor can make a diagnosis and give recommendations for treatment based on the individual characteristics of a particular patient.

    Before prescribing a patient a particular drug, it is necessary to familiarize yourself with a number of factors that provoke hypertension. So what affects blood pressure?

    • The volume of circulating blood. The high volume of circulating blood contributes to increased pressure.
    • Vascular tone. Hypertension occurs due to vascular spasm. The stronger the spasm, the higher the pressure. Arterioles directly affect the state of the vessels.
    • The functioning of the heart muscle. A fast heartbeat provokes an accelerated blood flow, therefore, as a result of this, blood pressure rises.

    Hypertensive patients are not recommended to prescribe treatment therapy on their own. Treatment, including drug therapy, should be prescribed only by a doctor.

    In most cases, doctors prefer those pills that you need to drink once a day. Their action lasts no more than 1 hours. Combined therapy, which includes taking several drugs, is not excluded. Thanks to such therapy, it is possible to significantly reduce the dosage of drugs and reduce the risk of side effects.

    Rauwolfia preparations: why their use is impractical?

    Arterial hypertension was previously reasonably treated with these medicines. The most popular remedies from this category are Raunatin, Reserpine. They are direct antispasmodics, which, in addition, provoke a delay in the body’s sodium and water. Taking this drug, you need to consider that it helps with pressure very slowly – the effect is noted only after 1-2 weeks.

    after starting treatment. Persistent drop in blood pressure is observed only in about a quarter of patients. Therefore, these drugs can not be considered a modern antihypertensive drug. However, there is another important factor why these pills are better not to use. The reasons are a large number of side effects that occur when taking such medications.

    So, there is evidence that when taking Rauwolfia drugs, the incidence of breast cancer has increased. It was also noted that when taking such drugs potentiation of the development of pancreatic cancer was noted. Therefore, in many countries drugs containing reserpine were banned. In addition to these negative effects, these drugs also cause the following side effects: drowsiness, nasal congestion, bronchospasm, gastrointestinal ulcers, arrhythmia, depression, edema, impotence.

    Stopping a hypertensive crisis

    Physiotens (moxonidine) at a dose of 0,4 mg or clonidine (clonidine) at a dose of 0,075-0,15 mg is also used. The last drug is used only in those who are chronically taking clonidine, which has been removed from treatment standards today.

    Today, a hypertensive crisis is not stopped by the intravenous administration of drugs or intramuscular injections of magnesia.

    Emergency measures include the following medications.

    What are the new cures for hypertension?

    When a patient reaches 60 years of age, it is customary to talk about primary hypertension, when elevated pressure indicators are the result of negative processes and age-related pathological changes in the cardiovascular system. Therefore, quite often medicines are immediately prescribed that can neutralize the symptomatic manifestations of the disease, and also have a complex strengthening effect on the “worn out” organism.

    When choosing medications, specialists try to choose a therapy in such a way that it includes new generation drugs. This is due to the fact that the latest antihypertensive drugs are created using revolutionary technologies and are characterized by an extremely high degree of effectiveness. The main innovation in the field of antihypertensive drugs was the following calcium channel blockers, which not only effectively fight the symptomatic manifestations of hypertension, but also improve the patient’s health indicators in general, characterized by an extremely modest list of side effects and contraindications.

    At this stage of the development of pharmacology, no antihypertensive drugs have been developed that would not have side effects. Nevertheless, new drugs for hypertension are safer and are characterized by such a number of advantages:

    • high performance indicators;
    • prolonged action;
    • complex effect.

    Relatively safe include the drug, which is included in the category of third-generation drugs – Physiotens. Its administration practically does not cause negative reactions from the patient’s body. In addition, it does not cause dry mouth and does not provoke increased drowsiness. It is also acceptable for use by people who suffer from diabetes mellitus or bronchial asthma.

    Based on some reviews, you can get information about the real side effects and the degree of their intensity on a real example of a person with arterial hypertension. Svetlana: As part of the treatment, I was prescribed Lisinopril, which refers to new drugs. He well and quickly enough lowers the pressure and has never given a side step.

    The result of the application completely suits me and I am satisfied. Valery: When my pressure began to jump, I went to the doctor. He discovered hypertension in me and prescribed a bunch of drugs, the main ones being beta-blockers. After that, my health became better and the differences almost did not bother. I did not hope for such a result.

    When can you do without a doctor?

    Other drugs are traditionally used in the treatment of arterial hypertension, which, in general, do not have pronounced features inherent in any particular group of antihypertensives. For example, the same dibazole or, say, magnesium sulfate (magnesia), which is successfully used by emergency doctors to stop a hypertensive crisis.

    Introduced into the vein, sulfuric acid magnesia has an antispasmodic, calming, anticonvulsant and slightly hypnotic effect. A very good preparation, however, is not easy to administer: it must be done very slowly, so the work stretches for 10 minutes (the patient becomes unbearably hot – the doctor stops and waits).

    For the treatment of hypertension, in particular, in severe hypertensive crises, pentamine-N (a cholinoblocker of sympathetic and parasympathetic ganglia, which reduces the tone of arterial and venous vessels), benzohexonium, similar to pentamine, arfonad (ganglioblocker), and aminazine (phenothiazine derivatives) are sometimes prescribed. These drugs are intended for emergency care or intensive care, so they can only be used by a doctor who knows their characteristics well!

    ACE Inhibitors

    Remedies for pressure of a new generation of this group of drugs are well-deserved. Recently, Alskiren has often been prescribed. If the correct dosages are observed, normal BP values ​​can be maintained all day. The drug has been clinically tested. Compared with ACE inhibitors, lower doses of renin inhibitors are required to normalize pressure.

    The modern medication is Fosinopril. But in terms of therapeutic effect, he does not manage to surpass “Lisinopril” and “Enalapril” invented more than 30 years ago. Fosinopril has fewer side effects compared to Enalapril. But the latter is more affordable, so its popularity among hypertensive patients does not decrease.

    Angiotensin-converting enzyme inhibitors (abbreviated as ACE inhibitors) are pharmaceuticals that are primarily used to treat high blood pressure and heart failure. This group of drugs inhibits the activity of the angiotensin-converting enzyme, which converts inactive angiotensin 1 into active angiotensin 2, thereby expanding blood vessels and reducing the load on the heart.

  • Ramipril.
  • Perindopril.
  • Zofenopril.
  • Quinapril.
  • Fosinopril.

    Despite the rather long introduction into clinical practice, these drugs continue to confidently lead among all ACE inhibitors, proving their high efficacy and safety in many studies. Moreover, many scientific evidence suggests that there are almost no significant differences in the effectiveness and safety of different ACE inhibitors.

    • Heart failure – these drugs reduce the burden on the heart.
    • Diabetic Nephropathy – ACE inhibitors help maintain the functional state of the kidneys.
    • Chronic Kidney Disease – ACE inhibitors can help slow the progression of these diseases.
    • Myocardial infarction.

    People who should not take ACE inhibitors:

    • Pregnant and lactating women.
    • Patients with hypersensitivity to these drugs.
    • Patients with certain kidney diseases – for example, renal artery stenosis.

    The most common side effect of all – even the newest – ACE inhibitors is dry cough, which develops in about 10% of people taking these drugs. Less common is swelling on the lips, tongue, or around the eyes, as well as impaired renal function.

    Beta blockers

    In comparison with Alskiren, the maximum therapeutic effect is achieved a month earlier.

    Drugs for hypertension of all groups have the main goal – to normalize blood pressure, in case of hypertension – to lower it. List of blockers: They have the greatest therapeutic effect. Medicines not only reduce blood pressure, but also additionally protect the organs that ensure the vital activity of the body.

    They are characterized by a prolonged action. Well tolerated by elderly patients. New drugs for high blood pressure do not accumulate calcium salts, do not completely wash out potassium. The group is represented by Trifas. The medication effectively reduces blood pressure in people in old age, as well as in diabetes. Compared to other diuretics, Trifas does not need to be taken often, just 1 tablet every morning is enough. Diuretics for new generation high blood pressure (list): But one must not forget that medicines can be taken only as prescribed by the doctor.

    To treat high blood pressure, doctors often prescribe new-generation combination drugs to patients.

    This group includes such drugs of the new generation for high blood pressure: Drugs for increased pressure of the new generation (the list is given above) are used for complex therapy. Compared to its predecessors, these medicines dilate blood vessels well, reduce the pulse. But they have one drawback – a pronounced symptom of withdrawal.

    The most common medication is Amlodipine. In the combination therapy “Lisinopril” with “Equator” there is a positive hypotensive effect. Blockers can be used in mono – or complex therapy. Medications improve metabolic processes, reduce the body’s need for excessive oxygen supply, so blood pressure does not increase.

    To reduce blood pressure, dihydropyridines, which were developed in the 1960s, are most often used. There are 4 generations of drugs from the nifedipine group:

    • 1st generation – nifedipine;
    • 2nd generation – nicardipine, felodipine;
    • 3rd generation – amlodipine;
    • 4th generation – cilnidipine.

    In clinical practice, drugs of the first three generations are most often used; doctors prescribe cilnidipine quite rarely. Amlodipine is perhaps the most often prescribed drug from the BCC group. It began to be used in 1990. Amlodipine has been shown to be highly effective in the treatment of hypertension, as well as safety.

    Cilnidipine is a new 4th generation drug from the BCC group, which has certain advantages over other calcium antagonists. Compared with the representatives of the first three generations, which affect only the L-type of calcium channels, cilnidipine can also block their N-type. This property can have useful clinical value, manifested by the suppression of reflex tachycardia and a decrease in edema, which is sometimes observed with the use of amlodipine and other, older, BCC.

  • 1st generation – propranolol, timolol, sotalol (non-selective, block beta-1 and beta-2 adrenergic receptors)
  • 2nd generation – metoprolol, bisoprolol, esmolol (selective, only beta-1 adrenergic receptors are blocked)
  • 3rd generation – carvedilol, nebivolol, labetalol (have additional vasodilating properties).

    Carvedilol is one of the third generation BB with the additional property of vasodilation. It acts on beta-1- and beta-2-adrenergic receptors, and also blocks alpha-adrenergic receptors in the vessels. Due to these effects, carvedilol reduces blood pressure more strongly, less affects the heart rate, does not increase blood lipids and glucose levels.

    The disadvantage of the drug is its effect on beta-2-adrenergic receptors, which increases the risk of bronchospasm. Carvedilol should be taken twice a day, which is not very convenient for the patient. Nebivolol is a drug that selectively acts on beta-1-adrenergic receptors, which additionally has vasodilating properties due to increased synthesis of nitric oxide (NO) in the vascular endothelium.

    Due to these effects, nebivolol reduces blood pressure better, has less effect on heart rate, does not increase blood lipids and glucose levels, and does not cause erectile dysfunction. A negative property of this drug is a rather weak effect on beta-blockers, so it is most often used in older people with heart failure.

    Labetalol is a drug with non-selective beta-blocking properties and an effect on alpha receptors. Labetalol is used primarily in the form of intravenous administration, in which it has a very short duration of action, which allows good control over the effects of the drug. This is the most effective beta blocker for treating hypertensive crises. It is often used for pheochromocytoma (an adrenal tumor) and preeclampsia (late toxicosis in pregnant women).

  • Svetlana Borszavich

    General practitioner, cardiologist, with active work in therapy, gastroenterology, cardiology, rheumatology, immunology with allergology.
    Fluent in general clinical methods for the diagnosis and treatment of heart disease, as well as electrocardiography, echocardiography, monitoring of cholera on an ECG and daily monitoring of blood pressure.
    The treatment complex developed by the author significantly helps with cerebrovascular injuries and metabolic disorders in the brain and vascular diseases: hypertension and complications caused by diabetes.
    The author is a member of the European Society of Therapists, a regular participant in scientific conferences and congresses in the field of cardiology and general medicine. She has repeatedly participated in a research program at a private university in Japan in the field of reconstructive medicine.