The risk of stroke remains largely unexplained, while data from large multicenter full-genome association studies indicate a significant contribution from genetic factors [52, 53]. According to these studies, from 16 to 40% of the phenotype variability in AI and from 34 to 73% in case of GI can be explained by the features of the genotype .
Most of the associations identified are specific for a certain type of AI and GI, although several risk loci have been found for any type of stroke . Identifying genetic options that predispose to stroke is the first step in developing diagnostic tests to identify the risk of stroke and innovative treatments that can help reduce the overall burden of the disease.
Further research in this area will reveal new phenotypes and describe the biological mechanisms of the disease, as well as expand the understanding of the genetic characteristics of stroke patients.
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