Comparing drugs to find out what is the difference between Mexidol and Cavinton, you need to pay attention to their composition. The main substance of Mexidol is ethylmethylhydroxypyridine succinate, which accelerates the metabolic processes in the brain and slows down the oxidative processes in the brain tissues.
Cavinton as a main component includes Vinpocetine, which also has an antioxidant and antihypoxic effect on brain cells. In addition, it reduces the viscosity of intravascular fluid, increasing fluidity and reducing the risk of vascular thrombosis.
The active substance of this drug is vinpocetine.
- stabilizes cerebral circulation;
- prevents the formation of blood clots;
- normalizes vascular tone;
- improves rheological qualities of blood;
- increases the flow of oxygen to the tissues of the brain and prevents the development of hypoxia.
Assign for diseases of a neurological profile: various signs of encephalopathy (regardless of the form of manifestation), grade 2 and 3 arterial hypertension, cerebral arteriosclerosis, and rehabilitation after a stroke.
Contraindications: arrhythmia, angina pectoris and bradycardia, acute hemorrhagic stroke, under 18 years of age, pregnancy and lactation.
Cavinton contraindications: arrhythmia, angina pectoris and bradycardia, acute hemorrhagic stroke, under 18 years of age, pregnancy and lactation.
- Adverse reactions and interactions with other drugs
- Contraindication factors of Mex >
- The best analogues
- Trental: analogues of the drug
- How to take Cavinton and Mexidol?
- Which is better?
- Patient Reviews
- Together or separately
- The effect of joint therapy
- Cavinton or Cinnarizine
- Actovegin or Cavinton
- The similarities of the compositions
- Piracetam or Cavinton
- Tanakan or Cavinton
- Can Cavinton be replaced by Mexidol?
- General information about Cavinton
Adverse reactions and interactions with other drugs
Cavinton is produced in 5 mg tablets and injections. The main substance is vinpocetine, which has the following therapeutic effects:
- improvement of cerebral circulation and metabolic processes;
- increased brain consumption of glucose and oxygen;
- increased resistance of nervous tissue to oxygen starvation or hypoxia;
- antioxidant effect;
- decrease in blood viscosity;
- improvement of cerebral blood flow;
- increased blood circulation without the effect of robbery in damaged areas;
- increased vascular elasticity.
In the recommended dosages, the medicine has practically no effect on blood pressure, heart rate, general peripheral resistance, minute volume of blood. Therefore, it is not contraindicated in arterial hypotension, arrhythmias. In severe forms of the disease, the doctor decides on the appropriateness of the appointment and replacement options.
The main active ingredient is ethyl methyl hydroxypyridine succinate. It belongs to the group of antioxidants. It increases the speed of metabolic processes in the brain and improves blood circulation in problem areas, slowing down the oxidation of fats, which prevents thrombosis. Isolates free radicals plying in the bloodstream, slows down the development of degenerative processes with age-related changes and CNS pathologies.
It has anticonvulsant activity and stabilizes the emotional state, relieves anxiety and irritation. Mexidol acts on the peripheral vessels, helps get rid of tinnitus and numbness of the extremities, and increases stress resistance. Helps the body withstand aggressive influences, cope with stress factors and recover from intoxications of various kinds.
Indications for use:
- acute and chronic cerebrovascular disorders;
- traumatic brain injury;
- acute stressful conditions and constant emotional instability;
- drug intoxication;
- vascular dystonia.
Contraindications for use: impaired hepatic or renal function, pregnancy and lactation. With frequent drops in blood pressure and Kawasaki’s syndrome, it is prescribed if the benefit of taking exceeds the possible harm.
The mechanism of action of Cavinton is based on its blocking of phosphodiesterase, an enzyme that regulates the content of cyclic nucleotides in the tissues of the human body. An increase in the cGMP pool caused by phosphodiesterase blocking causes muscle fibers to relax, the blood vessels to dilate, and the increase in the volumetric blood flow velocity in tissues subject to ischemia.
In addition, an increase in the content of cAMP in platelets is accompanied by a decrease in their aggregation, as a result of which the blood viscosity significantly decreases. The drug, interacting with the membranes of red blood cells, reduces their deformability.
After the course of treatment with Cavinton, a positive dynamics is observed in the analysis of indicators of neuropsychological tests: attention, memory improves, anxiety level decreases, the coefficient of social adaptation, performance increases. The drug also has a unique anti-inflammatory effect, modulating the activity of cytokine and chemokinergic intracellular systems.
The action of the second drug (Mexidol) is based on a combination of antioxidant and membrane-protective effects. Thanks to them, the lipid oxidation of cell membranes is inhibited and the links of prostaglandin synthesis change, the activity of antioxidant enzymes in the body increases and the ratio of cholesterol / phospholipids decreases, and the energy-saving function of mitochondria is activated.
Basically, all side effects are temporary and go away quickly. Most often, when using these drugs, the following undesirable effects are observed: dizziness, nausea, vomiting, headache, bitterness or dry mouth, decreased ability to work, which are usually temporary and disappear after dose adjustment. At the first signs of an overdose, you should immediately consult a doctor.
Drug Safety Studies
Both drugs are fully compatible with other drugs used for various somatic diseases. They are able to enhance the effects of both these drugs and each other. However, it is necessary to consult with a specialist, because in each specific case of interaction, a change in the daily dose of each of the medicines may be required.
Treatment with Cavinton can provoke the appearance of various side effects in the body.
The use of medication can cause:
- sleep disturbances;
- the appearance of a feeling of dizziness;
- bouts of nausea;
- blanching of the skin;
- the appearance of general weakness.
Mexidol therapy can cause nausea, fatigue, drowsiness, rashes on the skin, and itching.
Contraindication factors of Mex >
Cavinton helps to expand the cerebral vessels, increase blood flow, improve the supply of oxygen to the brain. In addition, it helps utilize glucose and reduces platelet adhesion.
Cavinton is prescribed for disorders that are associated with circulatory disorders of the brain, hypertension, vaso-vegetative spasms, memory disorders, dizziness, and speech disorders.
If we talk about the composition of this drug, it should be noted that it is based solely on plant components, which are combined under the name “vinpocetine”.
Despite the high efficiency of cavinton, many people prefer to choose its analogues. Why is this happening? There are analogues of cavinton that have:
- lower cost;
- fewer contraindications;
- fewer side effects;
- wider spectrum of action;
- other forms of release.
When deciding to search for similar drugs, it should be borne in mind that Cavinton is available in the following dosage forms:
- 5 mg tablets, in a package of 50 pieces;
- concentrate for solution preparation, in a package of 10 ampoules.
Pills cost about 200 rubles, while the concentrate will cost about 250-300 rubles.
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The best analogues
There are quite a few analogues of Cavinton Forte and other types in tablets and in solution, which have a similar principle of action.
In addition, this drug reduces platelet aggregation and provides oxygen transport to organs. The active substance is vinpocetine. Available as a solution for injection and tablets.
The cost of tablets is from 32 to 137 rubles. Concentrate for the preparation of the solution will cost 44-46 rubles. Based on this, the main advantage of Vinpocetine is that it is a cheaper analogue of Cavinton, although doctors say that Cavinton is more effective.
This drug costs about 3-4 times cheaper than cavinton, but it is no less effective to improve cerebral circulation. The medicine helps to improve metabolic processes in the brain and is characterized by antispasmodic action.
In addition, Bravinton can be used as a remedy for frequent dizziness, memory disorders, apraxia, frequent headaches. The active substance of the drug is also vinpocetine.
It is available in the form of tablets, a solution for intravenous administration, as well as a concentrate, which is used to prepare the solution.
The main active ingredient of this drug is also vinpocetine.
One of the analogues of Cavinton at which the price is lower. About once every 2. The drug is used to improve cerebral circulation, dilate the blood vessels of the brain, improve blood flow.
In addition, the drug relaxes blood vessels, which reduces the risk of ischemia and strokes. Available in tablet form.
This drug is actively used for labyrinthine disorders, tinnitus, dizziness, nausea and vomiting.
In pharmacy chains, this drug can be purchased for only 15-25 rubles. The active substance of this tool is cinnarizine. Available in tablet form.
- This drug helps to improve trophism, activation of metabolic processes in tissues, stimulation of regeneration processes.
- In fact, it is a deproteinized extract of calf blood, which includes derivatives of nucleic acids and low molecular weight peptides.
- It leads to the activation of cellular metabolism due to increased transport and accumulation of glucose and oxygen.
It should be borne in mind that Actovegin can be used not only intravenously or orally, but also externally, and this is its main advantage.
A medicine costs about 120 rubles.
It is a domestic product that is part of a new generation of antioxidant drugs. Mexidol and Cavinton are often used simultaneously to treat circulatory disorders of the brain.
Available in the form of tablets and injection. Tablets cost from 200 rubles, the solution will cost about 400 rubles.
To summarize the above, we can say that the best analogues of cavinton in tablets are drugs such as:
If you want to choose an effective solution for injection, you should pay attention to the following drugs:
- Separately, it is worth noting the drug Actovegin, which can be used not only for intravenous administration or taken orally, but also used as an effective external agent.
- Despite the fact that Cavinton is considered a fairly effective drug with a wide spectrum of action, many people prefer its analogues.
- The main reason is that domestic medicines with a similar effect are lower in cost.
Also, some of the analogues have a wider range of indications and are available in other dosage forms. In any case, the decision to use a specific medication should be made only by a specialist, focusing on the characteristics of your body.
When prescribing Cavinton, the presence of possible contraindications to the patient should be taken into account.
The medication is not recommended for the appointment:
- with severe arrhythmia;
- acute hemorrhage in the brain;
- heart ischemia.
The appointment of Mexidol is undesirable for patients with intolerance to sulfites and bronchial asthma.
Cavinton cannot be used for acute cerebral hemorrhage.
Mexidol is used for:
- acute violation of cerebral blood flow;
- injuries leading to concussion;
- dystonia of a vegetovascular nature;
- manifestations of a hangover syndrome, concomitant alcohol dependence;
- poisoning with antipsychotic drugs;
- correction of stress conditions.
All these conditions are usually accompanied by a cognitive impairment that occurs as a result of impaired normal blood flow in the cerebral region. Mexidol contributes to the normalization of the process.
Mexidol is contraindicated for pregnant women in all three trimesters, as well as for lactation, and for people with high levels of liver and kidney failure .. Prescribing the drug to people with unstable blood pressure is possible only with constant medical supervision.
However, only the attending physician has the right to make the final decision about which names to replace the drug with if necessary.
The scope of Cavinton includes, first of all, pathologies of neurological origin. These include:
- Post-stroke conditions of various etiologies, both of ischemic and hemorrhagic nature.
- Atherosclerotic lesion of cerebral vessels.
- Encephalopathic manifestations of post-traumatic and hypertonic nature.
- Chronic hypertension of the second and third degree.
- Chronic dysfunction of the vestibular apparatus.
In such cases, specialists often recommend that patients take Mexidol and Cavinton at the same time.
Doctors do not prescribe the drug when patients:
- have not reached the age of eighteen;
- are pregnant at any time or lactation;
- suffer from severe forms of cardiac arrhythmias, other cardiovascular pathologies;
- experiencing an acute period of hemorrhagic stroke, which ends about a week after the person suffered a hemorrhage.
All of them have similar properties.
For each of these drugs, indications and contraindications for treatment are clearly stated in the instructions for use. Cavinton is widely used in clinical practice. The main indications for its use are:
- Chronic post-stroke conditions.
- Hypertensive encephalopathy and chronic brain ischemia.
- Neurological and mental disorders in patients with cerebrovascular insufficiency.
- Vertebrobasilar insufficiency, vegetovascular dystonia.
- Vasovegetative symptoms in menopause.
- Vascular eye diseases, including glaucoma.
- Toxic or organic hearing loss, senile hearing loss.
- Meniere’s disease.
Contraindications – individual intolerance, pregnancy and lactation. With caution and in a minimal dose, the drug, especially parenteral, should be used for severe coronary disease and severe cardiac arrhythmias.
The second drug, Mexidol, has pronounced positive effects in the treatment of patients with various forms of cerebrovascular disorders:
- Parkinson’s disease.
- Multiple sclerosis.
- Chronic post-stroke condition.
- Encephalopathies, the cause of which are injuries, decreased blood flow, inflammation.
- Neurocirculatory dystonia in hyperkinetic or hypokinetic types.
- Decrease in cognitive properties: memory, thinking, attention.
Contraindications to the use of Mexidol are as follows:
- Pregnancy and lactation.
- Allergic reactions to the components of the drug.
- Terminal disruption of the kidneys or liver.
Both drugs are contraindicated in childhood and are used only from 18 years old.
In the treatment of vascular dementia and cerebral vascular insufficiency, the effective dosage range of Cavinton can range from 10 to 50 mg / day. In diseases of the Alzheimer’s type, the daily dose is increased to 60 mg / day. Tablets are taken 3 times a day after meals, with plenty of water. The average duration of treatment should be 3 months.
The injection form of the drug is strictly forbidden to enter intramuscularly and intravenously in a jet. Applied only for intravenous drip. The 20 mg ampoule is pre-mixed with 500 saline or Ringer’s solution. The rate of administration should not exceed 80 drops per minute. The prepared solution can be used within 3 hours.
Mexidol should be taken at 125-250 mg per day. The maximum allowable amount of drunk tablets per day should not exceed 6 pcs. The average duration of use is 1,5 months.
Also, the drug is administered intravenously. The ampoule of the drug is diluted with 100 ml of saline or 5% glucose and administered within an hour. In the case of an intravenous jet route of administration, it should be remembered that Mexidol is administered slowly.
Trental: analogues of the drug
Trental is an angioprotector that corrects myocirculation. The drug prevents the formation of blood clots, dilutes the blood and saturates the cells with oxygen. There are many analogues of Trental. These are Cavinton, Mexidol and Sermion. To understand which drug is better, you need to consider the features of each of them and get acquainted with the reviews of patients and doctors.
Trental is an angioprotector that activates blood circulation. The main component of the drug – pentoxifylline increases blood flow by affecting red blood cells, inhibiting platelet aggregation and reducing blood viscosity.
Trental increases microcirculation and saturates tissues with oxygen mainly in the central nervous system, limbs and kidneys. Also, the drug helps to expand the coronary vessels.
Trental for osteochondrosis is often used. This disease occurs with dystrophy of the articular cartilage.
Pentoxifylline acts on the vascular walls, increasing patency of the arteries and increasing microcirculation. This leads to a large amount of oxygen and nutrients entering the pinched area, thereby accelerating the regeneration of the affected vertebrae.
The drug is available in tablets and ampoules. The highest concentration of pentoxifylline in the blood after use is noted after 60 minutes. The drug is excreted mainly by the kidneys.
Trental is used for impaired peripheral circulation of a diabetic and atherosclerotic nature (angiopathy, lameness). Another indication is cerebral ischemic diseases (exclusion of Alzheimer’s disease and other types of dementia).
Also, an angioprotector is prescribed for trophic disorders, such as an ulcer, gangrene, malfunctions in the blood circulation in the vessels and the retina. Trental is prescribed for pathological bone growth and hearing impairment arising from vascular diseases.
Contraindications to taking the drug:
- Heavy bleeding
- Pentoxifylline Intolerance
- Retinal hemorrhage
- Age to 18 years.
Trental in ampoules is administered infusion. A single dosage is 200-300 mg (2/3 ampoules of 5 ml) either. Pentoxifylline is diluted in a solution of Ringer or sodium chloride. The medicine is administered iv twice a day.
Trental tablets are taken up to 3 times a day, up to 400 mg at a time. The permissible dosage per day is 1200 mg.
After applying Trental, a number of adverse reactions may occur. This is facial hyperemia, gastrointestinal upset, tachycardia, allergic reactions. Dizziness, sleep disturbance, thrombocytopenia, bleeding, hypotension, and headache are also possible.
When considering whether Trental or Cavinton is better, you should know the features of each remedy. The fact is that both drugs are not absolute analogues, but they have similar indications.
So, Cavinton, like Trental, dilates blood vessels, which can prevent the development of a stroke. Also, drugs normalize the brain, eliminating cramps and pain syndromes. Both drugs thin the blood and reduce platelet aggregation.
Vincetetin-based Cavinton is available in the form of tablets and concentrate for the preparation of an infusion solution. With cervical osteochondrosis, Cavinton is prescribed to improve the rheological properties and enhance blood circulation in the pathological area.
Pills are taken after meals 5-10 mg three times a day. The minimum dose per day is 15 mg, the maximum is 30 mg. The duration of treatment is 1-3 months.
The solution is injected iv slowly with a dropper at a rate of up to 80 drops per minute.
Despite the similarity in the indications, the drugs have differences. From a safety point of view, Cavinton is better than Trental, since it is a dietary supplement and has a minimal number of adverse reactions and contraindications.
In special cases, Cavinton and Trental are prescribed together. This combination increases the effectiveness of treatment and promotes positive dynamics. In this case, practically no negative reactions occur. Although doctors claim that Trental affects the entire vascular system, and Cavinton has a positive effect only on brain activity.
Mexidol contains ethylmethylhydroxypyridine succinate. The medicine protects cells from free radicals and other destructive factors. The effectiveness of the drug is quite high, since it has a number of therapeutic effects – nootropic, stress-protective, antioxidant, antiepileptic and antihypoxic.
This allows you to take tablets or administer Mexidol drug solution with:
- Cerebrovascular accident
- Vascular lesions of the brain
- Withdrawal syndrome
- Tissue hypoxia
Mexidol is contraindicated in children under 12 years of age, with acute renal or hepatic failure, pregnancy, or lactation. The drug has virtually no side effects. Only occasionally after taking allergies, nausea, xerostomia can occur.
It is impossible to say that Trental or Mexidol is better. Since drugs have a different therapeutic focus.
But compatibility Mexidol and Trental is possible. In the complex, the antioxidant and angioprotector enhance each other’s action. Moreover, the combination of these drugs is especially effective in multiple sclerosis.
Sermion is used for vascular and metabolic disorders. These are disorders of peripheral blood flow, limb atheopathy, headache, Raynaud’s disease, embolism or thrombosis of cerebral vessels, dementia and so on.
In case of cerebrovascular accident, Sermion tablets are used three times a day, 10 mg each. The duration of therapy is from 90 days. With vascular dementia, the medicine is drunk twice a day for 30 mg for about six months.
The lyophilisate is used as follows:
- In / in – 4-8 mg up to 4 times a day
- V / m – 2-4 mg twice a day
- B / a 4 mg is administered for two minutes.
Side effects after taking Sermion are rare. Sometimes there is hypotension, abdominal pain, sleep disturbance, dizziness. Contraindications – childhood, acute bleeding, pregnancy, myocardial infarction, bradycardia, low blood pressure, lactation.
Considering the question of what is better Sermion or Trental, it is worth noting that these drugs belong to the same drug group. Therefore, drugs have a similar therapeutic effect.
Testimonials from patients’ doctors say that sharing drugs is unacceptable. Indeed, the simultaneous use of Trental with Sermion can lead to a decrease in their effectiveness, disrupt the functioning of the heart and increase the risk of bleeding.
If the medication is not suitable, you should inform your doctor and choose an effective, authorized replacement. Analogues of the drug Cavinton are dispensed from pharmacies according to a specially designed prescription, have restrictions on the purpose and side effects.
A list of what Cavinton can be replaced with, indicating the form of release, estimated cost and producing country
|Analogue||Form of issue||Price in rubles||Manufacturer country|
|Cavinton||pills, injections||230 – 350||Hungary|
|Cavinton forte and comfort||conventional and dispersible tablets||250 – 850|
|Vinpocetine||injection pills||35 – 90||Russia, Belarus|
|Mexico||injections tablets||250 – 2300||Russia|
|Cinnarizine||pills||40 – 100||Russia, Bulgaria|
|Actovegin||ampoules, tablets||550 – 1650||Russia|
|Pyracetam||tablets, capsules, ampoules||30 – 200|
|Fezam||capsules||240 – 450||Serbia|
The domestic drug Noopept refers to nootropic drugs. One of the therapeutic actions is to improve learning, memory, attention, and prevention of amnesia. Also, the medication reduces the frequency of headaches, tachycardia, staggering gait, increases the resistance of brain tissue to oxygen starvation and damaging factors.
Imported drugs Trental and Wazonit, the Russian analogue of Cavinton Pentoxifylline are used to restore blood circulation and dilate blood vessels. As a result, medications improve the condition of patients, reduce the frequency of night cramps, headaches, and increase the distance of walking.
Medicines Cerebrolysin and Cerepro are nootropic drugs and are available in ampoules, capsules. Analogs are prescribed by a doctor for complaints of forgetfulness, impaired memory and attention, brain injuries, dementia and some organic diseases.
Ampoules and capsules of Mildronate tone, improve mental and physical performance, increase blood circulation in the focus of ischemia, dilate blood vessels. They are used as an additional tool to improve the quality of life of patients with complaints of fatigue and lack of strength, cardiovascular diseases, and a deterioration in the blood supply to the brain.
Despite the fact that Vinpocetine has a low cost and a fairly high efficiency, some people prefer to choose analogues that have a similar effect. Why is this happening?
Vinpocetine analogs have:
- fewer contraindications;
- wider spectrum of action;
- other forms of release;
- fewer side effects;
- higher bioavailability.
When deciding on the search for similar drugs, it should be borne in mind that vinpocetine is available in the following dosage forms:
- the concentrate from which the solution for infusion is prepared – 35 rubles;
- pills – 19 rubles.
There are many effective analogues of Vinpocetine.
It is used to improve cerebral circulation, it has a vasodilating, antiaggregational, neuroprotective, antihypoxic effect. It enhances blood flow in the brain, improves the supply of oxygen to this organ.
In addition, Cavinton helps reduce platelet aggregation and reduce high blood viscosity, increases the plasticity of red blood cells.
The main active ingredient is vinpocetine.
The price of this analogue of Vinpocetine is incomparably higher. This drug costs about 200 rubles.
The main advantages of this drug are the rapid accumulation of the maximum level in the blood, high bioavailability in comparison with similar drugs, a variety of release forms.
Cavinton is released in the form of tablets and a solution that is used for intravenous administration. The only drawback of the drug is the relatively high cost.
- It has a vasodilating, antihypoxic, antiaggregatory effect.
- It promotes relaxation of the smooth muscles of the cerebral vessels, enhances blood flow, improves hypoxia tolerance, increases the supply of oxygen to the brain.
- This drug is usually used for circulatory disorders of the brain, memory disorders, dizziness, aphasia, headaches, motor disorders.
- The active substance of vinpoton is vinpocetine.
- Available in the form of tablets in a bottle and costs about 250 rubles.
- The main advantages of this drug are its high bioavailability in comparison with similar products, a convenient form of release, and the rapid accumulation of the required level in the blood.
- However, it also has certain disadvantages, among which it is worth highlighting the high cost and the only form of release.
How to take Cavinton and Mexidol?
Which drug to choose? Therefore, in this article I want to highlight this issue in more detail. So, what is better to choose Cavinton or Fezam? Separately, I would like to consider some issues, for example, the safety and efficacy of drugs. But about everything – below.
For many years, unsuccessfully struggling with pain in the joints.
Head of the Institute: “You will be amazed how easy it is to cure the joints by taking the drug for 147 rubles every day .
Vinpocetine and Mexidol are used for circulatory disorders of the brain. These drugs belong to the group of nootropic drugs, have the same mechanism of action, but are manufactured by different manufacturers.
Vinpocetine and Mexidol are used for circulatory disorders of the brain.
Both drugs belong to psychoanaleptic drugs that are used for cerebrovascular accidents. The active substances in these drugs are different, so they are considered analogues having the same therapeutic effect. You cannot take these drugs together, because their interaction can cause adverse reactions.
- improves cerebral circulation;
- improves performance;
- prevents the occurrence of neurological and vascular diseases.
It is made in the form of tablets and ampoules for injection. In 1 tablet – 5 mg of vinpocetine. The medicine increases the supply of oxygen and nutrients to the brain cells, has an antiplatelet, vasodilating effect.
Mexidol is an antioxidant with nootropic and anticonvulsant properties.
The active substance is ethylmethylhydroxypyridine succinate:
- normalizes blood microcirculation;
- improves metabolic processes;
- lowers cholesterol in the blood;
- prevents the formation of blood clots.
This drug activates intellectual activity, improves memory and concentration. The medication has several dosage forms. The product has a quick effect and has a long lasting effect.
Mexidol activates intellectual activity, improves memory and concentration.
Both drugs are used to treat the same diseases, but their effects on the body are different. Also, drugs have a different composition. Vinpocetine has nootropic and metabolic properties, it improves cerebral circulation.
Mexidol has pronounced antioxidant properties.
- inhibits the activity of free radicals;
- prevents the destruction of cell membranes;
- has antihypoxic, anticonvulsant, nootropic properties.
The drug also has a sedative effect, eliminates anxiety, depression, fatigue. The medication improves the body’s resistance to aggressive factors: intoxication with alcohol and medicines, ischemia, shock, hypoxia.
Vinpocetine treats impaired circulation, it is prescribed for:
- insufficiency or spasm of cerebral vessels;
- vascular occlusion;
- memory impairment;
- pathology of the eye vessels;
- hearing impairment;
- Meniere’s disease.
Vinpocetine treats impaired blood circulation, it is prescribed for: cerebrovascular insufficiency or spasm; dizziness; headache; vascular occlusion.
Mexidol is used in the treatment of:
- consequences of cerebrovascular accident;
- complications of head injuries;
- atherosclerosis, anxiety disorders;
- withdrawal syndrome with alcoholism;
- asthenic conditions;
- to protect the body under stress and increased stress.
Both drugs can be used in the treatment of cerebrovascular disorders, but since they have different effects on the body, it is difficult to determine which is more effective. These medicines should be prescribed by your doctor.
The cost of drugs in pharmacies:
- Mexidol tablets 50 pcs. (Russia) costs 380-400 rubles., Ampoules 5 pcs. – 500 rub.
- Vinpocetine, concentrate for a solution of 5 mg / ml 2 ml 10 pcs. (Russia) – 48 rubles.
- Vinpocetine tablets 5 mg 50 pcs. (Russia) – 51 rubles.
- Vinpocetine tablets 5 mg 50 pcs. (Belarus) – 56 rubles.
Which is better?
Mexidol appeared on the pharmaceutical market later than vinpocetine. The first drug in the manufacture passes several stages of purification, which is why it is the safest. Mexidol has an improved mechanism of action, does not cause adverse reactions, such as vinpocetine. Therefore, of the 2 drugs, Mexidol is considered the best.
Nikolay Semenovich, neurologist, Ulyanovsk
Vinpocetine restores blood flow in brain tissue for ischemia, atherosclerosis, encephalopathy and conditions after a stroke. Its advantage is a natural base – an alkaloid obtained from a small periwinkle plant.
Valentina Sergeevna, neurologist, Yoshkar-Ola
Both drugs are highly effective and cause a minimum number of adverse reactions, there are also few contraindications for these drugs. Many patients taking these medications report an improvement in their condition and a reduction in negative symptoms.
Galina Andreevna, neurologist, Ivanovo
These funds are intended to improve blood circulation of the brain, treat varicose veins, eliminate frequent headaches, they are effective, have few adverse reactions and are often prescribed in clinical practice for the treatment of patients with the consequences of ischemic stroke. Patients after therapy note improvement, increase in working capacity, they quickly switch to a normal life and restore their health.
Olga Stepanovna, 57 years old, Perm
Mexidol was prescribed to her husband after a stroke to treat consequences such as impaired speech, movement, and memory. He took medications in dosages prescribed by a doctor. After the course of treatment, the condition became better, speech and memory returned to normal.
Nikolay, 43 years old, Ussuriysk
After a traumatic brain injury, doctors diagnosed cerebrovascular accident. Vinpocetine was prescribed for treatment. After the entire course of therapy has passed, the negative symptoms – headache, dizziness, tinnitus – have passed. I feel good now. This is an excellent drug, I recommend it to people with similar diseases.
Gleb Alekseevich, 56 years old, Chelyabinsk
I have been suffering from cerebral arteriosclerosis for several years. I periodically undergo treatment with Vinpocetine. This is a good drug, it does not cause adverse reactions, it acts gently and effectively. After taking the medicine, the condition improves, headaches, dizziness pass, insomnia disappears, intracranial pressure normalizes.
This medicine is intended to restore blood flow in the soft tissues of the brain during ischemic attacks, vascular atherosclerosis, encephalopathy, dementia and post-stroke conditions. One of the advantages of the considered product is its natural basis – the active ingredient is an alkaloid secreted from the grass of the small periwinkle.
Not all analogues of the drug Vinpocetin are developed on the basis of natural components, but they are no less effective and cause a small number of side effects, have few contraindications. Experts recommend the following medications:
Let’s consider each of them in more detail.
Cavinton or Vinpocetine – which is better and which is safer?
It is believed that these two drugs are completely identical. In Cavinton, the same active substance as in Vinpocetine, and, in a similar concentration. At the same time, the latter costs almost 3 times cheaper than a foreign medicine.
- Nevertheless, neurologists are more likely to prescribe Cavinton, because the degree of purification of the plant alkaloid in this medication is higher, respectively, taking it more safely.
- Which is better – Piracetam or Vinpocetine?
- Interestingly, these drugs are often recommended to be taken in parallel or as part of a single drug (for example, Fezam).
Piracetam, in fact, is a nootropic medication that has a beneficial effect on metabolic processes in the brain tissue, helps to increase the ability to concentrate, remember, improves memory.
In combination with the positive effect of Vinpocetine for the vascular system, such combined preparations are recommended in the treatment of a large number of diseases associated not only with circulatory disorders, but also metabolic processes.
Vinpocetine or Cinnarizine – which is better?
The described analogue also belongs to a number of nootropics, but according to the mechanism of action it is almost identical to Vinpocetine. However, Cinnarizine is prescribed less often due to a synthetic, rather than a natural basis, more side effects and an impressive list of contraindications.
It is worth noting that the generic presented is not recommended to be included in therapeutic regimens for the treatment of transient ischemic attacks, strokes and cerebral edema due to poor performance.
Vinpocetine or Mexidol – which is better and what to choose?
- Thus, of the two drugs under consideration, specialists prefer to prescribe Mexidol or its generic (Mexiprim).
- Which is better – Picamilon or Vinpocetine?
- This analogue is also used for cerebrovascular accidents, and for psychoemotional disorders, alcohol withdrawal, and vegetovascular dystonia.
Picamilon has a mechanism of action similar to Vinpocetine, but it provokes a large number of side effects from the central nervous system. At the same time, the drug does not help with such severe brain pathologies as stroke, ischemic attacks, neuro- and encephalopathies.
The drug Vinpocetine, as well as Mexidol, are associated with nootropic, psychoanaleptic drugs used in various fields of medicine in cases of cerebrovascular accident.
Medicines contain different active substances, so they are referred to analogues with the same therapeutic effect.
Mexidol and Vinpocetine should not be taken at the same time, since the interaction of both nootropics increases the risk of side effects.
Vinpocetine is a medicine from the group of psychoanaleptics, the use of which can improve cerebral circulation, increase efficiency, and reduce the risk of developing cardiovascular and neurological pathologies.
The drug is available in the form of tablets and ampoules for injections. One tablet contains 5 mg of vinpocetine.
Together or separately
Patients are worried about whether it is possible to take medications together and whether it will worsen their health conditions. According to available information, both types are complementary medicines, so they can be included in a single therapeutic course. However, although the compatibility of Mexidol and Cavinton allows their combined use, manufacturers consider it necessary to warn users about the undesirability of simultaneous administration. At the same time, unwantedness does not at all mean complete contraindication – it will be enough to just use them at different times of the day.
The effect of joint therapy
Doctors usually advise taking Mexidol and Cavinton together in case of persistent increase in blood pressure, i.e. in diagnosing hypertension. In this case, there is an improvement in blood circulation, acceleration of metabolic processes in the tissues of the brain, they become more resistant to hypoxia, i.e. lack of oxygen.
Cavinton or Cinnarizine
Cinnarizine is a medicine from the group of “slow” calcium channel blockers. This means that the product dilates blood vessels without affecting blood pressure, improves blood supply to organs and tissues, muscle resistance to oxygen starvation, reduces blood viscosity and strengthens the elasticity of red blood cell membranes.
In general, the properties of Cavinton and Cinnarizine are similar. Both remedies are prescribed to reduce the unsteadiness of the gait caused by disorders of the vestibular apparatus, tinnitus, dizziness, headache and migraine. Cinnarizine analogue is cheaper, available only in tablets. What to choose depends on the condition of the patient and is determined by the doctor at the appointment.
Actovegin or Cavinton
The analogue of Cavinton in ampoules and tablets is Actovegin. The medicine is based on the selected active substance from the blood of calves.
The similarity of the two analogues lies in the effectiveness in violation of cerebral circulation, especially with atherosclerosis, ischemia.
There are differences in readings. Which is better depends on the patient’s complaints and the severity of the condition. Actovegin is used for atherosclerosis of vessels, trophic changes, peripheral angiopathy. Cavinton is often prescribed to eliminate the shakiness of gait as a result of impaired coordination and the vestibular apparatus, tinnitus and dizziness.
The similarities of the compositions
The drugs do not have similarities in composition. The active compound in Mexidol is a succinic acid salt. It is able to inhibit lipid oxidation processes and reduce the amount of oxygen needed by cells of brain structures.
The active component of the drug ensures the complete oxidation of glucose and normalizes the synthesis of nucleic acids.
Restoring the proper functioning of cells allows normalizing the transmission parameters of the nerve impulse and improving brain activity in the event of organic disorders.
The use of Mexidol is indicated to reduce the likelihood of developing cerebral thrombosis, which is achieved by the amount of free radicals and low density lipoproteins.
The neuroprotector Cavinton is based on vinpocetine. The active compound of the drug improves metabolic processes, normalizes blood circulation in the brain tissue, lowers the degree of blood viscosity and prevents the formation of blood clots. The use of the drug reduces the need for cells in oxygen.
Cavinton is recommended to be prescribed if the patient has:
- Chronic post-stroke conditions of various etiologies.
- Hypertensive encephalopathy and ischemia of brain tissue in a chronic form.
- Neurological and mental disorders in patients with cerebrovascular insufficiency.
- Vertebrobasilar insufficiency and vegetovascular dystonia.
- Vasovegetative symptoms during menopause.
- Vascular diseases of the eye, including glaucoma.
- Toxic and organic hearing impairment.
- Meniere’s Disease.
The use of Mexidol is indicated to reduce the likelihood of developing cerebral thrombosis.
Mexidol is recommended for use with:
- With Parkinson’s disease.
- Multiple Sclerosis.
- Chronic post-stroke condition.
- Encephalopathy, the cause of which are injuries, decreased blood flow and the occurrence of an inflammatory process.
- Neurocirculatory dystonia in hyperkinetic or hypokinetic types.
It is also recommended to take the drug with a decrease in cognitive properties – memory, thinking, attention, and if the patient develops glaucoma.
The differences are not limited to the active substances of different groups. Caviton is used only during the rehabilitation period after a stroke and is not used in the acute stage, unlike Mexidol. This drug has a much wider scope for circulatory disorders and CNS pathologies. However, it cannot be introduced into the therapeutic regimen in case of violation of the urinary system and liver dysfunction.
The similarity of the drugs is explained by:
- Scope. Used in the treatment of brain pathologies.
- The form of release is tablets and injectable solutions.
- Low allergic risk.
- Compatibility with pharmaceuticals used to stop vestibular disorders and dizziness, in which betagistin is the active ingredient.
Medicines are considered analogues due to the fact that they are prescribed for the same pathologies.
Piracetam or Cavinton
Piracetam is a drug in injections, capsules and tablets to improve memory, attention and concentration, to facilitate the learning process. The analogue is cheaper than Cavinton, protects brain cells from damage by toxins, alcohol, due to shock, hypoxia and other factors.
Cavinton also has a nootropic and damage-protecting effect. However, the main purpose of the drug is to improve blood circulation in the brain, the elimination of related symptoms.
What is better Cavinton or Piracetam, depends on the complaints and the patient’s condition. Perhaps combined use, also in pharmacies are complex preparations containing both piracetam and vinpocetine, for example: Omaron, Fezam.
Tanakan or Cavinton
Both drugs are prescribed for cerebrovascular disease and memory impairment, attention. There are differences in analogues:
- Cavinton is a vinpocetine-based chemical. Tanakan – based on the ginkgo biloba plant.
- the first medication has a quick formula, soluble in the oral cavity, called “comfort”.
- different manufacturers – in the first case Hungary, in the second Russia.
- excellent incidence of side effects.
Thus, Tanakan is a safe analogue, less often leads to undesirable consequences. In serious cases, doctors give preference to Cavinton, using the analogue for prophylactic purposes or as an additional measure.
Can Cavinton be replaced by Mexidol?
If the doctor prescribed one of the drugs, then it is not recommended to replace it with another one yourself. They are not chemical analogues. But, if there are any problems, a correction of the therapeutic regimen is possible.
To achieve a lasting result, use 2 drugs at the same time. This does not cause the patient any inconvenience – the use is not associated with food intake. If drug solutions are injected, they are filled into different syringes.
General information about Cavinton
Cavinton is a synthetic analogue of an alkaloid isolated from a medicinal plant – small periwinkle. Widely used in clinical practice by neurologists and therapists.
Cavinton is effective in the treatment of discirculatory encephalopathy, regardless of the stage and etiological factor of chronic vascular insufficiency of the brain, since the clinical effect of Cavinton is due to the vasomotor effect and the effect on the functional activity of the brain.
The drug is produced in the form of tablets and a solution for injection. The active substance is vinpocetine. Tablets are available in aluminum blisters, 50 pieces per pack, the dosage of the active component is 5 mg. Additional components are also present: talc, magnesium stearate and corn starch. Injection Cavinton is dosed at 5 mg / ml of the active substance, in a package of 10 ampoules of 2 ml.
Mexidol is a synthetic antihypoxant whose protective effect is due to the presence of succinic acid. This medication has a wide range of pharmacological effects and a multifactorial mechanism of action, implemented at two levels – neuronal and vascular. It is widely used in neurological, therapeutic and cardiological practices.
The active substance is ethylmethylhydroxypyridine succinate. The form of release is an injection solution of 2 and 5 ml in an ampoule, as well as coated tablets, 125 mg of the active component. The package contains from 5 to 10 ampoules. Additional components of the drug are povidone, magnesium stearate.
Detonic – a unique medicine that helps fight hypertension at all stages of its development.
The complex effect of plant components of the drug Detonic on the walls of blood vessels and the autonomic nervous system contribute to a rapid decrease in blood pressure. In addition, this drug prevents the development of atherosclerosis, thanks to the unique components that are involved in the synthesis of lecithin, an amino acid that regulates cholesterol metabolism and prevents the formation of atherosclerotic plaques.
Detonic not addictive and withdrawal syndrome, since all components of the product are natural.
Detailed information about Detonic is located on the manufacturer’s page.