Angiomyolipoma of the kidney what is it, is it life-threatening and how to treat it

The most typical neoplasm in the kidney is angiomyolipoma. Its look does not depend upon gender and age, however individuals from 40 to 60 years of ages and pregnant females are most prone to this illness.

Sometimes these neoplasms can appear both in the adrenal glands and in the pancreas. But these cases are so uncommon that angiomyolipoma is primarily associated to kidney illness.

  • Therapies
  • Prevention
  • What is angiomyolipoma and its category

    Angiomyolipoma is a benign growth that impacts muscle and fat, along with capillary, as an outcome of which the latter lose their shape and do not perform their functions. Over time, this neoplasm for numerous factors can turn into a deadly type.

    According to the worldwide analytical category of illness ICD 10, angiomyolipoma refers to growths of fats and has the following coding – M8860/0 (D17).

    These neoplasms are genetic and obtained. In the very first case, the growth starts to establish in the womb, for that reason, it impacts 2 kidneys at the same time. With the obtained nature of the illness, neoplasms in 75% of cases impact just one kidney, for that reason, when making a medical diagnosis, it is required to suggest in which kidney the growth is situated.

    The threat of angiomyolipoma

    Due to their benign nature, such neoplasms in themselves do not damage the body and, at little sizes, might not manifest themselves for a long period of time. However, with the development of the growth, the blood circulation in the kidney substantially degrades, as an outcome of which some of its parts might pass away, which will lead to interruption of the organ’s performance.

    Also, with a sharp development of the neoplasm, the kidney ruptures, due to which internal bleeding is formed, which can lead to the death of an individual. In addition, in this case, there is a high likelihood of the growth deteriorating from a benign type into a deadly one with its spread to other organs.

    Causes of angiomyolipoma

    The primary factors due to which an angiomyolipoma appears in the kidney are:

  • Genetic irregularities. The primary factor for the look of neoplasms in babies.
  • All kinds of kidney illness that are connected with inflammatory procedures in muscle tissue.
  • Oncology of the human urinary system.
  • Violation of the hormone background of a lady throughout pregnancy.
  • Natural age-related death of adipose and muscle tissues.
  • Insufficient blood circulation due to constricting of the capillary.

    However, the system of the development of such growths by doctors is not completely comprehended. Therefore, in time, the list of factors will just grow.

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    Symptoms of the illness

    As discussed above, with a little size, the growth does not have noticable signs. However, with its development, more than 5 cm, ruptures start to appear in the vessels and tissues, which trigger hemorrhages in the body. Such procedures are accompanied by:

    • Redness of urine, due to the ingress of blood into it.
    • Inconsistency of high blood pressure due to blood loss. As an outcome of low high blood pressure, lightheadedness and fainting might take place.
    • Pallor of the skin and anemia.
    • Pain in the lower back and abdominal area. The discomfort is specifically intense when flexing and turning the body.

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    For any such signs, it is required to speak with a medical professional as quickly as possible for a medical diagnosis and assessment with an expert.

    Diagnostic treatments

    To identify the nature, size and position of the neoplasm, physicians perform an entire variety of numerous diagnostic treatments. These consist of:

  • Organ ultrasound (ultrasound).
  • X-ray.
  • Blood and urine tests.
  • Computed and magnetic resonance imaging (CT and MRI).
  • Ultrasound angiography.
  • Biopsy.

    Each diagnostic technique is required at a specific phase of the client’s assessment.

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    Ultrasound assessment

    Ultrasound is one of the most typical types of research study for the main decision of the existence of irregular developments. When performing it, the medical professional can precisely identify the degree of the illness, and likewise choose more treatment. The essential benefit of this technique in relation to others is the lack of radiation throughout its application.

    X-ray

    X-ray, like ultrasound, is the main technique for identifying growths. The image plainly reveals the size and position of the anomaly. Recently, they are attempting to change this type of assessment with an ultrasound scan, because throughout it an individual gets a little dosage of radiation.

    Blood and urine tests

    Based on the outcomes of blood and urine tests, it can be concluded that there are inflammatory procedures in the body, along with whether there are internal bleeding triggered by the development of neoplasms.

    CT and MRI

    These diagnostic approaches are utilized when surgical elimination of the growth is needed. They enable you to get a three-dimensional image of an abnormality in an organ in numerous airplanes. Such research studies assist to localize and get rid of angiomyolipoma with very little repercussions for the body.

    Ultrasound angiography

    Ultrasound angiography is utilized to analyze the vessels in an organ. This research study makes it possible to identify their possible pathologies and structural modifications. When dealing with growths, it is required to entirely get rid of the vessels with flaws, because a neoplasm can establish from them once again.

    Biopsy

    This type of assessment assists to identify the nature of the neoplasm. For research study, a little piece of tissue of the abnormality is pinched off. After studying it, it is concluded that the growth is benign or deadly.

    Therapies

    Treatment of kidney angiomyolipoma has 2 instructions – medicamentous and surgical. The option of the type of treatment depends upon the size and development rate of the irregularity, along with the basic condition of the organ.

    Drug treatment is utilized in case of asymptomatic course of the illness, lack or irrelevant tumor development, along with its little size, which does not go beyond 4 cm. The course of treatment is performed with inhibitors and is created for a year. This technique does not entirely get rid of the illness, however assists to stop the development of the anomaly, and in many cases, to lower it.

    In cases where drug treatment does not provide outcomes, and there is no development of the anomaly, drugs are stopped and the client is designated yearly assessments to screen the advancement of the growth.

    Surgical intervention is required with the quick development of the neoplasm, its size is more than 5 cm, along with with the look of internal bleeding due to rupture of capillary and organ tissues. One of the following approaches is picked depending upon the course of the illness:

  • Embolization. This strategy includes clog of capillary connected with angiomyolipoma, which leads to a downturn in its development, and in many cases, to a decline in size. This technique is primarily utilized to localize abnormalities prior to partial or total resection and enucleation.
  • Enucleation. Removal of angiomyolipoma is performed without damaging the nearby tissues of the organ. This technique must be performed by an extremely certified cosmetic surgeon, because if even a little piece of the growth stays, then it can establish once again.
  • Partial resection. An approach in which a part of the kidney with a problem is got rid of. This technique enables you to keep the health of the organ, albeit to an insufficient level.
  • Cryoablation. They started to usage it reasonably just recently. The essence of the technique is to get rid of the anomaly in little parts, utilizing a compound with a low temperature level. This technique is ideal for little angiomyolipomas.
  • Complete resection. If it is difficult to get rid of the neoplasm without entirely interfering with the working of the kidney, it is got rid of completely. It is really essential that the 2nd kidney operates usually and does not have any irregularities.

    Prevention

    Since the system of the look of neoplasms is not completely comprehended, there are no particular suggestions for avoiding their look. In this case, physicians suggest more cautious, refers to all kinds of illness and inflammatory procedures in the kidneys, and likewise go through an ultrasound scan a minimum of when a year, for the prompt detection of the existence of abnormalities.

  • Svetlana Borszavich

    General practitioner, cardiologist, with active work in therapy, gastroenterology, cardiology, rheumatology, immunology with allergology.
    Fluent in general clinical methods for the diagnosis and treatment of heart disease, as well as electrocardiography, echocardiography, monitoring of cholera on an ECG and daily monitoring of blood pressure.
    The treatment complex developed by the author significantly helps with cerebrovascular injuries and metabolic disorders in the brain and vascular diseases: hypertension and complications caused by diabetes.
    The author is a member of the European Society of Therapists, a regular participant in scientific conferences and congresses in the field of cardiology and general medicine. She has repeatedly participated in a research program at a private university in Japan in the field of reconstructive medicine.

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