Rehberg’s test is one of the methods for analyzing renal excretory ability, which is used to diagnose impaired renal function.
Paul Reberg proposed a method of urinalysis, which was based on the assessment of the ability to filter and reabsorb (reabsorption) by the rate of excretion of intravenous creatinine per unit of time.
Subsequently, EM Tareev improved this method, replacing intravenous administration with indices of its own creatinine in the body, which made it possible to simplify and expand the possibility of using the method in the diagnosis of kidney diseases. In this regard, the method was named the Reberg – Tareev test.
Main indications and contraindications for implementation
The Reberg-Tareev test is used by specialists as a diagnostic method for making the correct diagnosis in a number of diseases of the urinary system.
This type of study is prescribed for patients with a history of complaints about:
- Decrease in urination and the volume of excreted urine against the background of the usual drinking regimen.
- Swelling of the lower extremities and face not associated with food intake and time of day.
- Increased blood pressure, disturbances in the work of the heart.
- Discoloration of urine, the appearance of an unpleasant odor, as well as blood, mucus, pus.
- Back pain, abdominal pain.
- Limb tremor.
- General malaise, weakness, fatigue.
- Nausea and vomiting for no apparent reason.
This research method allows you to evaluate:
- General condition and performance of the kidneys in acute and chronic diseases.
- The presence and nature of endocrine diseases.
- The body’s ability to recover from high physical exertion.
- Functioning of the kidneys in identifying pathologies of the functioning of the cardiovascular system.
- The efficiency of the kidneys in various acute and chronic diseases of the urinary system during pregnancy.
Using this method, in the absence of any symptoms, the doctor can identify the disease, establish its stage and degree of development.
This method of urine analysis is quite effective, has no contraindications and age restrictions. The exception is the period of menstruation in women. In the case when a woman has menstrual flow, the analysis is postponed until it ends.
How to properly prepare for delivery
Preparation before taking a sample consists in observing several rules:
- Follow a diet, you should exclude fried, spicy, salty foods, as well as alcohol from the diet.
- Avoid heavy physical exertion, do not lift weights, do not attend sports training.
- On the eve and during the period of the test, do not drink coffee, tea, juices, sugary drinks. You can drink water.
- Before taking, if possible, do not use medicines, and if they are taken, you should inform your doctor about it.
- Drink plenty of water.
Correctly performed preparation will allow you to get a reliable result, which in turn will affect the timing and correctness of the diagnosis.
Rehberg test, passing rules
Reberg-Tareev test involves donating blood from a vein. The basic rule when donating blood is that the process is carried out on an empty stomach in the morning. In this case, you should not eat food eight hours before taking the test. Blood is donated once, since the creatinine indicator changes slightly during the day. Before passing urine, you should perform a genital toilet.
Rehberg’s test, how to collect urine?
The Reberg-Tareev test involves collecting urine during the day.
There are several options for collecting urine for research:
- Urine collection is performed during the day from 6 am one day to 6 am the next. In this case, the first portion of urine is not collected, and all subsequent ones are collected in one large container. Next, you need to donate blood for the analysis of creatinine indicators. Make sure the urine collection container is clean and the collected urine is kept in the refrigerator. Next, it is necessary to determine the total volume of collected urine, and after thoroughly mixing it, pour about fifty milliliters into a separate container, which should be sent to the laboratory. On the container with urine sent to the laboratory, its total daily volume is indicated.
- The urine is collected twice, at an hourly interval. In each sample, the time of collection of fluid in minutes and the values of creatinine in the urine are determined.
- It is mainly used for scientific purposes. The method is similar to the first option, and consists in dividing the collected urine into night and day portions.
Sample index values
The result of the Rehberg-Tareev test is the determination of an indicator characterizing the ability of the kidneys to filter their main function. The indicator is called the glomerular filtration rate (GFR). The unit of measurement is milliliters per minute. The study results depend on the sex and age of the patient.
The main boundaries of normal values for different groups of people (ml/min) were determined:
- Children of the first year of life GFR from 65 – 100.
- From one to thirty years GFR 88 – 146.
- From thirty to forty years old GFR 82 – 140.
- Forty to fifty years GFR 75 – 133.
- Fifty to sixty years old GFR 68 – 126.
- Sixty to seventy years GFR 61 – 120.
- Over seventy years, GFR 55 – 113.
- From one to thirty years GFR 81 – 134.
- Thirty to forty GFR 75 – 128.
- Forty to fifty years GFR 69 – 122.
- Fifty to sixty years old GFR 64 – 116.
- Sixty to seventy years GFR 58 – 110.
- Over seventy years, GFR 52 – 105.
The result of the analysis and its decoding
The received data may differ from the normal values up or down. Based on these deviations, the doctor can conclude about the presence of the disease and the degree of its progress.
Increased rates, mainly indicate the possible presence of diseases such as:
- The initial stage of development of diabetes mellitus.
- Nephrotic syndrome.
- Hypertonic disease.
However, there may be objective reasons and conditions due to which the value of the indicator can be increased:
- Taking medicines, including some types of antibiotics, diuretics.
- Violation of the rules for preparing for delivery, for example, exercise, violation of the rules for eating.
- Burns and trauma to large areas of the skin.
Reduced rates are typical for renal failure of varying degrees.
In cases where GFR is abnormal:
- More than 30 ml/min, indicates a moderate decrease in the efficiency of the organ and the development of compensated renal failure.
- From 15 ml/min to 30 ml/min, indicates subcompensated renal failure,
- Less than 15 ml/min, indicates that the organ develops its resource and decompensated renal failure develops, for example, against the background of violations of the cardiovascular system.
The GFR result established by the Reberg-Tareev method should be taken into account when making a diagnosis, along with other methods for diagnosing diseases.
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