In cardiological practice, it is recommended to combine the use of Potassium Orotat with magnesium.
The drug is not intended for use as a potassium-containing drug in potassium replacement therapy.
Potassium Orotat blunts the absorption of sodium fluoride, iron and tetracycline. The therapeutic efficacy of the drug is reduced while taking oral contraceptives, diuretics, muscle relaxants, insulin and glucocorticosteroid drugs.
The instructions to Potassium Orotat indicate that it is necessary to store the drug in a dark, cool, dry and inaccessible place for children. Shelf life is 48 months.
It is released from pharmacies in an over-the-counter mode.
A solution of Potassium chloride 4 and 10% is released (i.e., every 100 g contains 4 and 10 grams of potassium, respectively) in bottles – for infusion, in ampoules – for injection and oral administration. In addition, it is worth noting that in addition to the solution, in the pharmacy network you can find Potassium chloride in the form of a concentrate for the preparation of an infusion solution, coated tablets and prolonged-action capsules.
Potassium chloride 5% is not released.
The main active ingredient of the drugs is potassium salts. But, it is important to pay attention to the form in which they are contained here. The amount of pure potassium will depend on this. Its 1 gram is contained in: • 2 grams of potassium chloride; • 3,3 grams of potassium citrate; • 6 grams of potassium gluconate; • 4,4 grams of potassium orotate.
Potassium can be contained in preparations as an independent active substance and in combination with other components no less important for the body. Which version of the composition to choose – should be decided together with the appropriate specialist – nutritionist. This is the only way to achieve the desired result.
|Retard tablets 1 g||1 table.|
|potassium chloride||1 g|
|(Corresponds to the content of K 524,44 mg (13,3 mmol))|
|excipients: silicon dioxide, colloidal anhydrous (Aerosil 200) – 10; polyvinyl butyral (Movital B 30T) – 57,5; cetyl alcohol – 17; magnesium stearate – 1; talcum powder – 8|
in blister strip packaging 10 pcs.; in a cardboard box 1 package.
- Pharmacological properties of potassium chloride
- Side effects
- Contraindications for use
- special instructions
- In pregnancy
- For children
- Instructions for the use of potassium preparations
- Full-fledged work of organs: necessary substances
- Keeping of
- How to take Potassium Orotat
- Orotat Potassium in bodybuilding
- >derivatives nitrofuran, oxyquinoline, quinolone;
- Drug Interactions
- The price of potassium preparations and how to buy them
- Potassium Normin
- Synonyms of nosological groups
Pharmacological properties of potassium chloride
Potassium preparations have numerous properties that are valuable to the body of an ordinary person and athlete. They are as follows: • stabilization of the heart, reducing the excitability and conductivity of the myocardium; • strengthening of blood vessels and increasing their permeability; • stabilization of blood pressure in the vessels; • increasing the elasticity of bone tissue;
• increase contractility of muscles; • stimulation of the functionality of enzymes; • normalization of the processes of transmission of nerve impulses; • restoration of proper functioning of the kidneys; • maintenance of healthy skin; • normalization of water balance in the body; • effective cleansing of the body of toxins accumulated here;
• ensuring proper nutrition of the brain and all organs and systems of the body with oxygen; • neutralizing the negative effects of sodium on the body during its overabundance; • increasing the stamina of the body, which facilitates easier perception of intense physical exertion; • improving appetite;
Another important point: potassium has a very useful helper, such as sodium. In combination, these components have the following effect: sodium retains fluid in the body, potassium pumps it into muscle cells. Due to this, a beautiful muscle relief is formed, active muscle growth is stimulated. That is why potassium preparations are widely used among professional athletes. They are used no less than carbohydrates and proteins, which are also very popular, are produced in the form of numerous sports supplements.
Due to its many beneficial properties, potassium preparations are widespread, and are also often used in complex therapy of various pathologies. But, it is important to take the funds correctly in order to achieve the maximum effect, to exclude the development of side effects.
The pharmacy has a large selection of potassium-containing drugs, so it’s easy to find a suitable version of analogues from Russian and foreign manufacturers. Orokamag contains potassium and magnesium. Normalizes metabolic processes, improves the condition of the heart. Assign in complex therapy for the treatment of coronary heart disease. It has many contraindications and side effects, so it is taken only after appointment by a specialist.
The medicine “Kalinor” is necessary to replenish potassium reserves in the body. Assign with arrhythmias. Available in effervescent tablets. Before use, you should familiarize yourself with contraindications and side effects.
The group of diuretics includes Triapmur Compositum tablets. The active substances triamteren and hydrochlorothiazide retain potassium in the body. One of the disadvantages is the inability to use during pregnancy and while breastfeeding. This is a combined remedy, so you can reduce the dose by reducing the number of side effects. The dosage is selected by the doctor depending on the indications. Assign with high blood pressure, edema caused by problems with the liver, kidneys, heart.
“Torasemide” is a moderate-acting diuretic. Assign for swelling caused by heart failure. The effect occurs a few hours after application. Tablets relieve swelling, increase diuresis. Valid for 18 hours. It is allowed to take until puffiness has completely subsided. It has good absorption in the digestive tract. Among the disadvantages are the inability to use under reduced pressure. Causes a breakdown of the nervous system, a violation of the digestive tract.
Prevention and treatment of diseases with the help of potassium and magnesium preparations protects the heart, brain, helps with hypertension, diabetes, arrhythmia, coronary heart disease. Medicines in which two components are most effective. Well tolerated by patients, relatively safe, have a small number of side effects with the right dosage.
In accordance with the instructions for Potassium Orotat, the active component of the drug is potassium orotate. Excipients that make up the drug are potato starch, milk sugar, edible gelatin, stearic acid.
Potassium Orotat is an anabolic substance whose components have a stimulating effect on metabolic processes in the body. The drug takes an active part in the processes of protein, carbohydrate and lipid metabolism.
The active component of the drug, potassium orotate, is one of the precursors of the pyrimidine bases of the protein synthesis process (thymine, uracil, cytosine). The participation of the active substance in carbohydrate metabolism is due to its effect on galactose metabolism. Potassium Orotat and its salts, as compounds of anabolic action, are used to normalize the processes of protein metabolism, and also as a stimulator of the metabolic process.
According to reviews, Potassium Orotat provokes an improvement in appetite and tolerance of cardiac glycosides. When using Potassium Orotat, metabolism is activated, as well as reparative and regenerative processes.
During pregnancy, Potassium Orotat is recommended to fill the deficiency of potassium in the blood.
When using Potassium Orotat, it is not fully absorbed in the gastrointestinal tract, since only 10% of the total dose taken is absorbed. It is metabolized in the liver with the formation of orotidine-5-phosphate. It is excreted through the kidneys.
|Heading ICD-10||ICD-10 disease synonyms|
|E87.6 Hypokalemia||Hypokalemia Arrhythmia|
|Hypokalemic neuromuscular disorders|
|Hypokalemia in ketoacidosis|
|Hypokalemia in the treatment of saluretics|
|Potassium loss during saluretic therapy|
Potassium is the main intracellular ion, which is directly involved in the regulation of various body functions. It plays an important role in maintaining intracellular osmotic pressure, in skeletal muscle contraction (especially with myasthenia gravis and muscular dystrophy), in the process of transmission and conduction of a nerve impulse to innervated organs, in the transport of amino acids, protein-synthetic reactions, and a number of other biochemical processes. Also, potassium reduces the conductivity and excitability of the myocardium.
A solution of Potassium chloride is a tool designed to fill in the body a deficiency of potassium and restore water-electrolyte balance. This drug has a moderately diuretic effect, has a negative bathmotropic and chronotropic effects. When using the drug in small doses, potassium dilates the coronary vessels, in large doses it narrows them, and also has a negative dromo- and inotropic effect.
There is no information about an overdose of the stimulator for protein synthesis; it is well tolerated. Perhaps the manifestation of certain side effects, in the presence of which you should consult a doctor:
- allergic reactions that disappear after treatment;
- nausea, vomiting, mild digestive upset;
- dystrophy of the liver when taking large doses on a background of a diet containing little animal protein.
Inside. The dose is set individually depending on the disease and the concentration of potassium in the blood plasma. 1-2 g/day (based on potassium chloride), if necessary, increase the dose to 6 g/day.
Symptoms: hyperkalemia (muscle hypotension, paresthesia, slow AV conduction, arrhythmias, cardiac arrest). The early clinical signs of hyperkalemia usually appear when the serum K concentration is more than 6 meq/l: sharpening the T wave, broadening of the QRS complex.
More severe symptoms of hyperkalemia – muscle paralysis and cardiac arrest – develop at a concentration of K 9-10 meq/l.
Treatment: inside or in/in – sodium chloride solution; if necessary, hemodialysis and peritoneal dialysis.
The specific dose of the drug is determined based on the indicator of potassium in the blood plasma. The deficiency of this element is calculated by the doctor according to a special formula. The required amount of Potassium chloride 4 or 10% is diluted with water and injected dropwise (at a speed of 20-30 drops per minute). It is also possible to dilute Potassium chloride with 5% glucose or 0,9% sodium chloride. The recommended daily dosage, as a rule, does not exceed 20 mmol of potassium per hour or 2-3 mmol of potassium per 1 kg of body weight.
In emergency cases (and these include the threat of hypokalemia, diagnosed ECG measurements and/or marked muscle paralysis), as well as with a serum potassium level of less than 2,0 mg/l, the dose of Potassium chloride can be increased to 400 mg/day or 40 mg/hour. Such administration of the drug is carried out under the strict supervision of medical personnel, with frequent checking of the level of potassium in the blood plasma and ECG monitoring – these measures are required to prevent cardiac arrest.
Inside usually take a solution of Potassium chloride 10% 15-20 ml three or four times a day. According to indications, the dosage can be increased to 60-120 ml. If, for some reason, the next dose of the drug was missed, then proceed as follows: if no more than 2 hours have passed, take the recommended dose at the same time with liquid or food, if more than 2 hours have passed, skip this dose and return to the usual regimen. The standard daily dose for oral administration is 50-150 ml. As the therapeutic effect develops, the dose of the drug is reduced.
Reception of Potassium chloride in doses exceeding recommended is fraught with the development of hyperkalemia, manifested by paresthesia of the extremities, arrhythmia, muscle hypotension, and a slowdown in AV conduction. Possible cardiac arrest.
Potassium Orotat is for oral use. Adults are prescribed 1-3 tablets (0,5-1,5 g, the daily dose should be divided into 2-3 doses) 1 hour before or 4 hours after a meal. In individual cases, depending on the effectiveness of therapy, the daily dose can be increased to 6 tablets (3 g).
For children with alimentary-infectious and alimentary dystrophy, anemia, during the period of convalescence, the daily dose of the drug is prescribed in the calculation of 0,01-0,02 g per 1 kg of the child’s weight. The daily dose should be divided into 2-3 doses.
During pregnancy, Potassium Orotat should be taken 1 tablet 2-3 times a day. During treatment, constant monitoring of the daily volume of fluid taken and urine excreted is necessary.
In the reviews of Potassium Orotate, it is reported that when taking the drug in amounts exceeding the prescribed, liver dystrophy may develop, which requires stopping the drug.
It is well adsorbed from the digestive tract,
bioavailability – 80%, maximum
blood concentration after 1-2 hours.
It penetrates well into all organs and
tissue. Maximum amount
accumulates in the lungs, kidneys, liver,
the muscles. Penetrates well through tissue
barriers and into the cerebrospinal fluid.
Occurs by acetylation. By
acetylation rates, all patients
are divided into so-called “fast” and
“Slow” acetylants, which is deterministic
genetically. In “slow” acetylants
– with the same dose administered
the concentration of isoniazid in the blood is higher
than the “fast.”
stability is formed after 30
days from the start of the drug, for
warnings must be combined
isoniazid with other drugs.
pyridoxine metabolism due to binding
with pyridoxalphosphate, when this occurs
sensitivity and tingling in
warnings of the above
Pyridoxine (at a dose)
due to the formation of ammonia –
the level of liver enzymes rises
reactions: dermatitis, agranulocytosis,
Broad-spectrum antibiotic, has
bactericidal action against
mycobacteria, acts on extracellular
and intracellular bacteria.
action of rifampicin: associated with
suppression of RNA synthesis.
After ingestion, it is easily and practically in any quantity passively absorbed (absorption – 70%), because its concentration (both food and drug-free) is higher in the lumen of the small intestine than in the blood. From the tablets, the retard is gradually and slowly released throughout the digestive tract. In the ileum and colon, K is secreted into the intestinal lumen according to the principle of conjugated exchange with Na and excreted in bile (10%). The distribution of K in the body lasts about 8 hours from the time of administration. T1/2 in the absorption phase – 1,31 h; retard tablets release time – 6 hours
After oral administration, potassium is readily absorbed in almost any amount (approximately 70%), since its concentration in the lumen of the small intestine is higher than in blood plasma. The half-life is 1,5 hours.
According to the instructions, Potassium Orotat is well tolerated by the body.
In the reviews of Potassium Orotate, it was noted that in individual cases dyspepsia and allergic reactions may occur, accompanied by a skin rash, itching, peeling, and swelling. Side effects from the body are short-term and when the drug is canceled, they quickly disappear. If necessary, if side effects are manifested in the form of an allergy, antihistamines are prescribed.
As stated in the reviews about the electrolyte solution, it can provoke the development of negative reactions of the body, such as:
- Nausea, vomiting, abdominal pain, flatulence, diarrhea, obstruction and perforation of the intestine, ulceration of the gastrointestinal mucosa;
- Myasthenia gravis, paresthesia, confusion;
- Arrhythmia, decreased blood pressure, heart block;
- Hyperkalemia and allergic reactions.
reactions: rash, eosinophilia,
action at the injection site;
(up to seizures, more often
resistance is fundamental when
antibiotic treatment. At the heart of
the formation of resistance of microorganisms
to β-lactam antibiotics
lies the ability of microorganisms
– enzymes that destroy antibiotics.
To prevent occurrence
penicillins resistance combine
with β-lactamase inhibitors
(clavulanic acid – Sulbactam).
– a group of antibiotics, derivatives
hepatotoxicity, especially in individuals with
liver disease in patients
alcoholism in the elderly;
autoimmune origin – treatment
carried out under the control of coagulation
reactions (itching, rash, redness);
renal failure, while
stop taking this drug;
accelerates the metabolism of analgesics,
antidiabetic agents and
close to isoniazid but
its activity is lower. Renders
dyspeptic disorders, causes
abdominal pain, flatulence, nausea.
Less effective than
isoniazid and rifampicin. Is acting
only on mycobacteria located in
Actions: reduces the synthesis of RNA.
small doses of side effects.
There is a decrease in visual acuity,
disturbed light vision. In connection with
decreased uric acid excretion
exacerbation of gout.
PASK. Turning on
in combination with others
reduces the likelihood of drug development
sustainability. Competing with PABK
mycobacteria, causes bacteriostatic
the effect. PASK is neutralized by hydrochloric
stomach acid observed
dyspeptic disorders, possible
proteinuria, crystalluria, hepatitis,
action on the digestive tract;
(chloronitrophenol). Apply topically
with dermatomycosis, use alcohol
It is a cationic detergent,
applied topically as an ointment or powder.
about 200 types of helmittes.
(nematodes) – cause nematodes.
tapeworms (cestodes) – cause
flukes (helmatods) – cause
helminths to a macroorganism:
In the process
when fixing in
Gastrointestinal tract cause ulceration of the mucous membranes
membranes, circulatory disorders;
lumen of hollow organs;
affect blood, gastrointestinal tract, nervous
reactions especially in patients with
addiction to them;
carried out by the body
remedies are medicines
having a selective effect on
certain types of helminths used
for the treatment of helminth infections of various
From the gastrointestinal tract: nausea, vomiting, diarrhea, flatulence, abdominal pain, ulceration of the gastrointestinal mucosa, gastrointestinal bleeding, perforation and bowel obstruction.
From the nervous system: paresthesia, muscle weakness, confusion.
From the cardiovascular system: lowering blood pressure, arrhythmias, heart block, cardiac arrest.
Other: hyperkalemia, allergic reactions.
Contraindications for use
The instructions to Potassium Orotat indicate that the drug should not be taken in patients with renal failure, cirrhosis of the liver with ascites, nephrolithiasis.
Potassium Orotat is not prescribed to people who have hypersensitivity to the components of the drug.
First of all, you need to understand who and when you need potassium salts. This will avoid hyperkalemia, which leads to numerous negative consequences. So, indications for potassium intake are: • frequent urination, leading to a violation of the water-salt balance; • poisoning, accompanied by vomiting and diarrhea;
• increased fatigue, which occurs even with minor physical exertion, is often manifested by weakness in the legs; • violation of the frequency and rhythm of heart contractions (arrhythmia); • systematic increase in blood pressure; • frequent seizures localized in the lower extremities;
• constant stresses contributing to the development of nervous tension; • disturbances in the functioning of the respiratory system; • intense physical exertion leading to active sweating; • exercise in a hot room or in the summer; • multi-day competitions and lengthy workouts;
In the presence of such indications, taking potassium preparations will be fully justified. But first, you should definitely consult a doctor. This will allow you to choose the right tool, as well as determine the optimal dosage, which makes it possible to achieve the desired result, to eliminate the likelihood of side effects.
Despite the fact that potassium is a substance that plays an important role in the life of the body, taking it in the form of drugs acting as an additional source of macronutrients is contraindicated in some cases. The use of potassium salts is strongly not recommended in such situations: • hyperkalemia, which may be a consequence of renal failure and other disorders.
It is manifested by increased sweating, arrhythmic conditions, frequent urination. Also at this time, gastric colic, increased irritability may be observed. In this case, you should undergo an examination and refuse to take potassium. The prolonged presence of hyperkalemia becomes fertile ground for the development of diabetes;
• violation of the excretory function of the kidneys associated with the presence of certain diseases in the body. In such a situation, the risk of developing higher than the considered hyperkalemia is increased • individual intolerance to the components of the drug. It manifests itself with symptoms of an allergic reaction, which may include problems with the respiratory system, digestion or skin integument.
As for the side effects, they are quite rare. Symptoms usually develop in response to exceeding the dosage that triggered an excess of potassium. Side effects include: • nausea, sometimes leading to vomiting; • diarrhea; • heart rhythm disturbances; • confusion;
When such symptoms appear, you should stop taking the drug, visit a doctor and undergo an examination to exclude hyperkalemia. Avoiding such symptoms is quite simple – you need to adhere to the recommended dosage and duration of potassium intake.
Potassium preparations should not be used for:
- Adrenal insufficiency;
- Full AV blockade;
- Chronic renal failure;
- Metabolic disorders (such as hypovolemia with hyponatremia, acidosis);
- Erosive and ulcerative diseases of the gastrointestinal tract;
- Concomitant therapy with potassium-sparing diuretics.
Potassium chloride is not recommended for children and adolescents under 18 years of age, as well as for pregnant and lactating women.
inhibition of function
liver and kidney;
It is forbidden to use a medication in the presence of the following contraindications prescribed in the instructions:
- hypersensitivity to the components of the tool;
- acute, chronic damage to the liver, its failure, ascites;
- cirrhosis of the liver;
- individual intolerance, hypersensitivity to orotic acid and its derivatives;
- with caution in renal failure, pregnancy, breastfeeding.
Hypersensitivity to the drug, hyperkalemia, complete AV block, adrenal insufficiency, chronic renal failure, concomitant therapy with potassium-sparing diuretics, metabolic disorders (acidosis, hypovolemia with hyponatremia), erosive and ulcerative lesions of the gastrointestinal tract, pregnancy, breastfeeding, age up to 18 years.
The following analogues of Potassium Orotate are similar in therapeutic effect on the body, chemical composition and active substance:
- Riboxin solution and tablets;
- Alpha lipon;
- Glycine Ozone;
- Farcovit B12;
Medicines that are similar in therapeutic effect and chemical composition to Potassium Orotat are Potassium Orotoxicum, Orocid, Oropur and Dioron.
If potassium chloride is intended for oral administration, it should be taken with food or immediately after it, washed down with water. During the course of treatment with potassium-containing drugs, it is important to strictly adhere to the doctor’s instructions regarding nutrition. We must not forget that when determining the amount of potassium entering the body, its content in foods is also taken into account.
During treatment, it is necessary to control the content of K in the blood serum, ECG, KHS. Safety and efficacy of potassium chloride in children have not been established. A diet high in sodium chloride increases K excretion from the body. It should be borne in mind that hyperkalemia leading to death can develop quickly and be asymptomatic.
Instructions for use Potassium Orotate contains a section of special instructions that indicate the following important points for taking the drug:
- does not cause drowsiness, does not affect the speed of psychomotor reactions, the rate of muscle contraction;
- when treating with a medicine, a diet is required;
- a promising direction in cardiology is the use of Potassium Orotate in combination with magnesium;
- contraindicated in chronic renal failure, cirrhosis of the liver with ascites.
Detonic – a unique medicine that helps fight hypertension at all stages of its development.
The complex effect of plant components of the drug Detonic on the walls of blood vessels and the autonomic nervous system contribute to a rapid decrease in blood pressure. In addition, this drug prevents the development of atherosclerosis, thanks to the unique components that are involved in the synthesis of lecithin, an amino acid that regulates cholesterol metabolism and prevents the formation of atherosclerotic plaques.
Detonic not addictive and withdrawal syndrome, since all components of the product are natural.
Detailed information about Detonic is located on the manufacturer’s page.
Women carrying a child often have edema, which is why the use of the medication during pregnancy is justified. It helps to remove excess fluid from the body, to make up for potassium deficiency. The daily dose for pregnant women is one tablet 2-3 times a day. During therapy, the daily rate of drunk fluid and excreted urine should be constantly monitored.
The use of Potassium Orotate in childhood is possible according to the dosage regimen. Indications for use are anemia, alimentary-infectious and alimentary dystrophy, convalescence. The daily dose is divided into 2-3 times, is 0,01-0,02 g per kilogram of body weight of the child. The course of treatment is about 3-5 weeks, depending on the prescription of the doctor.
Instructions for the use of potassium preparations
According to the classification in medicine, Potassium orotate refers to metabolic drugs that normalize the metabolism. Available in tablet format, suitable for adults and children. Potassium Orotat is effectively used in sports because it contains an anabolic that stimulates the effects of protein molecules, carbohydrate and lipid metabolism in the body. The medication has an anabolic effect.
Potassium tends to accumulate in the body, therefore, it is taken in the form of special preparations with short-term courses, the duration of which should not exceed 3-4 weeks. As for the doses recommended for humans, they are determined individually. Everything will depend on the state of the body, the intensity of life and indicators of various loads, as well as the dosage of the drug itself. Usually it is advised to take the drug one capsule 1 to 5 times a day.
To determine the exact dose, it is worth noting that for an ordinary person, the daily rate of potassium is 1,5 grams. If we talk about athletes, then they need from 2 to 3 grams of substance. Based on these figures, the application scheme is calculated.
Take potassium supplements with meals, as well as before or after meals. It all depends on the form of release of the drug, the version of the active substance. After completing one course, a break of several months should be taken. The need for repeated use is discussed individually with a doctor.
If potassium is part of vitamin complexes, it is present here in a lower dosage, respectively, the duration of administration may be longer, or the time interval before the next course will become shorter. But, again, all these points are decided individually.
Full-fledged work of organs: necessary substances
Potassium is absorbed in the intestines, residues are removed with urine. The kidneys are the main organ that regulates the process of finding enough potassium in the body. Loss occurs with sweating, vomiting, and diarrhea. Derived from the abuse of alcohol, coffee and sugar. Potassium and magnesium preparations for hypertension in tablets are aimed at lowering blood pressure. For this medication is taken regularly for the time indicated by the doctor.
After potassium, magnesium is an important element. It regulates metabolic processes, helps maintain intracellular potassium concentrations. Both substances are interdependent, they are important for the body’s work, therefore vitamins and drugs with potassium, magnesium in tablets are often prescribed for patients with heart diseases, in case of seizures.
Diuretics are chosen because of the gentle action, unlike other diuretics. The composition of the preparations includes a substance necessary for the normal maintenance of the water-salt balance. They have a weak diuretic effect. They retain potassium in the body, so the heart does not break. Manufacturers offer a group of aldosterone inhibitors and drugs that affect membrane channels for treatment. They are taken in combination with thiazide diuretics as a prevention of hypokalemia.
How to take Potassium Orotat
The medication is prescribed inside one hour before a meal or four hours after a meal. The daily dosage for adults is 250-500 mg 2-3 times. The course lasts 20-30 days, is set individually, depending on the characteristics of the patient’s body. If necessary, therapy is repeated after a month. Exceptional cases can increase the adult daily dose to 3 g. If the symptoms of the disease persist, it is recommended to consult a doctor.
Orotat Potassium in bodybuilding
According to the instructions and reviews, it is allowed to take Potassium Orotat inside for athletes. In bodybuilding, the drug serves to eliminate intoxications, dermatoses, progressive muscular dystrophy, spastic conditions. It is recommended to take it when exposed to the body with increased physical activity, because the medication quickly restores the body and helps build muscle.
Bodybuilders before training combine medication with Riboxin, other vitamins (Sportwick), which increases the intensity of muscle growth. At the physiological level, potassium ions accelerate metabolism, improve appetite, strengthen the heart, and stimulate reparative processes. Take the drug half an hour before meals in the amount of one tablet, or after four hours from the moment of eating.
nitrofuran, oxyquinoline, quinolone;
(with an extended spectrum of action):
spectrum of action.
for the treatment of systemic mycoses:
for the treatment of dermatomycosis:
for opportunistic fungi (candidomycosis).
this group of drugs includes derivatives
imidazole and triazole.
for 15 years. Have a wide range
resorptive action, well tolerated.
Mechanism of action: act on the plasma membrane
fungal cells – the main structure
fungal membrane components not
a wide spectrum of action, has
fungistatic effect. Resistance
Forms of release
various drugs – drug
injection form, tablets, capsules,
ointments, creams, suppositories, alcohol solutions,
Side effects: local irritation of the mucous membranes,
hyperemia of the skin, allergic
resorptive dyspeptic reactions
violations, with iv management possible
for the treatment of intestinal helminthiases:
nematodoses are used:
cestodoses are used:
treatment of extraintestinal helminthiases:
treatment of trematodoses:
nematoses (intestinal lumen):
application of anthelmintic
with intestinal localization:
ensure close contact of the helminth
the use of anthelmintic drugs
should contain only easily digestible
body foods and drinks;
before taking drugs
need to cleanse the intestines with
drugs are used
drugs do not stimulate peristalsis
intestines, then after their administration is prescribed
saline laxatives and enema;
treatment is carried out
taking into account the life cycle.
– not having selectivity
antimicrobial action they
detrimental to most
microorganisms (antiseptics and
– antimicrobial drugs
disinfectants – drug group,
that are capable of holding back growth,
development or death of microorganisms
in the patient’s environment or on
the surface of his body.
– (anti- against; septicas– putrefactive). This is a group of medicinal
funds used for
eliminate pathogenic microbes in the wound
(skin, mucous membranes) in the digestive tract and
urinary tract. Depending on the
concentrations have bacteriostatic
or bactericidal action depending
medicines – serve
for medical disinfection
tools, utensils, rooms,
equipment, etc. Disinfection is
set of activities aimed at
prevention of infection in
a wound in the body as a whole or for
preventing the spread of infection.
the boundary between antiseptics and
disinfectants are not always
perhaps because many substances in low
concentrations used as antiseptics,
and at higher – for disinfection.
presented to antiseptics and
wide spectrum of action;
must have small
latent period of action;
lack of local
irritating or allergenic
actions on tissues;
absorbability from the place of their application;
Drugs (mefenamic acid) may interfere
absorption of other drugs as well
some food ingredients due
toxic effects on the mucosa
blood supply to the digestive tract (for example, in acute
or chronic heart failure)
may interfere with drug absorption, therefore
the appointment of drugs that improve hemodynamics
(cardiac glycosides, diuretics), may
increase the absorption of other drugs.
MAO (nialamide) in the mucosa
intestines increases absorption
tyramine (from food sources) and other
sympathomimetics serving as a substrate
MAO. Its quantity also decreases
liver, which is accompanied by an increase
bioavailability of sympathomimetics.
funds (adrenaline) add to local
anesthetics to slow down
absorption and prolongation
can interaction. directly in plasma
(protamine and heparin, deferroxamine and
iron, dimercaprol and arsenic).
for places of communication with plasma proteins. At
using two or more drugs, one of
which has a lower affinity for
protein, it is displaced. If
the drug is active, then it can displace
previously introduced drugs from places of contact with
proteins, and then the concentration of free
fractions of the first drug increases
and as a result, the pharmacological
activity (salicylates, butadione,
clofibrate is being forced out of association with protein
indirect anticoagulants and
increase the frequency of internal
Drugs displaced from association with protein
distributed in large volume then
increased plasma concentration of it
free fraction is not so significant
(imipramine (imizine) binds to proteins
95%, but it has a large distribution volume
(100 l/70 kg), therefore interaction with
other drugs displacing it from places
communication with proteins is not significant
effects often develop if crowding out
the drug is administered intermittently or in
different doses, and will be especially pronounced,
if you need to carefully monitor
plasma concentration of one of
preparations. Clinically Important Implications
may be if due to communication with proteins
anticoagulants are displaced or
oral hypoglycemic agents.
crowding out can occur at the level of
tissue proteins. Quinidine displaces
digoxin from the places of contact with them. Besides
Moreover, it disrupts digoxin excretion
kidneys, therefore, the risk is increased
digoxin toxicity if quinidine
prescribed without a corresponding reduction
doses of digoxin.
affecting the blood supply to organs and
tissues can disrupt the distribution
other drugs (in patients with congestive
CCH with the appointment of antispasmodic
funds in combination with cardiotonic
the effect of diuretics increases).
improving rheological properties
blood (trental, xanthinol nicotinate,
dipyridamole), reducing blood viscosity,
platelet and red blood cell aggregation,
contribute to a change in distribution
Drugs in areas of organs previously inaccessible
for the action of drugs due to violation
intrabronchial administration of drugs to patients
with the phenomena of bronchospasm along with
the use of specific drugs should
prescribe β-adrenostimulants that expand
bronchial and contributing
Drugs in the lower parts of the bronchial
so drug interactions can disrupt
drug distribution, promote
increase concentration in one area
and decline in another, which is not fraught with
only by reducing the severity of the effect,
but also the possibility of developing side
effects (use of antispasmodics
leads to redistribution of blood flow
and reduced drug delivery in
area supplied by sclerotic
vessel – “syndrome
more than 300 drugs that can affect metabolism
in the liver, inhibiting or stimulating
liver enzymes are sleeping pills
funds (barbiturates, chloral hydrate),
tranquilizers (diazepam, chlordiazepoxide),
antipsychotics (chlorpromazine, triftazine),
(butadione, amidopyrine), chlorinated
insecticides (dichlorodiphenyl trichloroethane
(DDT)), food additives, alcohol, coffee.
In small doses, some drugs
(phenobar6ital, butadione, nitrates may
stimulate your own metabolism
joint prescription of two drugs, one of
which hepatic enzymes induce,
and the second is metabolized in the liver,
the dose of the latter must be increased,
and if the inductor is canceled, reduce it.
A classic example of this interaction
– a combination of indirect anticoagulants
action and phenobarbital. It is proved that
in 14% of cases, the cause of bleeding with
anticoagulant treatment – drug withdrawal,
microsomal inducing enzymes
enzymes. To drugs that depress
activity of liver enzymes, include
narcotic analgesics, some
antibiotics (actinomycin), antidepressants,
cimetidine and others. As a result of application
combinations of drugs, one of which inhibits
liver enzymes, speed slows down
the metabolism of another drug, increase it
blood concentration and increased risk
So, the antagonist
histamine H2 receptors
cimetidine inhibits enzyme activity
liver and slows down the metabolism
which increases the likelihood of bleeding.
When using β-blockers in
combination with cimetidine occurs
severe bradycardia and arterial
Metabolism level drugs may
realized through change
hepatic blood flow. Any drugs
reducing regional hepatic
blood circulation reduces intensity
metabolism of drugs with severe
primary elimination effect
(propranolol, verapamil, etc.) and increase
their content in blood plasma.
Potassium-sparing diuretics, potassium preparations, ACE inhibitors, NSAIDs increase the risk of hyperkalemia. Reduces side effects of cardiac glycosides. Enhances the action of quinidine, a side effect of disopyramide.
The same annotation on the use of potassium salt indicates its drug interaction with other drugs:
- reduces the toxicity of cardiac glycosides;
- increases the effect of magnesium, calcium preparations, improves ion tolerance;
- astringents and enveloping agents reduce the absorption of potassium in the digestive tract;
- cardiologists recommend combining the drug with magnesium;
- not intended for use as a preparation with potassium content in potassium replacement therapy;
- slows down the absorption of sodium fluoride, iron, tetracyclines;
- its effectiveness is reduced when combined with oral contraceptives, diuresis agents, muscle relaxants, insulin, glucocorticosteroid drugs.
Slightly convex on both sides, disk-shaped tablets of white color with a marble pattern, with a bitter taste, odorless. The color of the fractured tablet is white.
All forms of potassium preparations and tablets containing potassium transfer the trace element to cells, accelerating metabolic processes. “Panangin” has proven itself in arrhythmias caused by a violation of the ionic composition. Assign with coronary insufficiency to adjust the number of trace elements when taking diuretics.
The pharmacy offers dragees and solutions for intravenous injection. It is very irritating to the digestive organs, therefore, it is necessary to take it strictly as prescribed by the doctor, without increasing the dosage after eating. Among the contraindications are cardiac arrhythmias, hyperkalemia, renal failure. “Panangin” is a therapeutic agent that prevents arrhythmia attacks, the expansion of the zone of damage to the heart muscle in acute heart attack. Reduces complications and mortality from heart failure.
The drug is indicated for post-infarction cardiosclerosis, arrhythmias, angina pectoris. Assign in the treatment of glycoside intoxication, with diabetes. Potassium-containing drugs are needed after a diuretic, which causes electrolyte loss.
You can not take with renal failure, dehydration, hypotension in the background of a shock condition. Not recommended after detecting an increase in the level of substances in the blood. Use caution when taking with other potassium-containing diuretics. With violations in the work of the digestive tract, the drug causes dyspeptic disorder, convulsions, hypotension. Before the appointment, the doctor writes out a referral for tests to make sure that there are no diseases that are on the list of contraindications.
Potassium reduces the excitability and conductivity of the myocardium, weakens the toxic effect of cardiac glycosides, without affecting their positive inotropic effect.
In small doses, K dilates the coronary vessels, in large doses it narrows. Participates in the process of conducting nerve impulses. It activates many cytoplasmic enzymes, regulates intracellular osmotic pressure, protein synthesis, amino acid transport. Improves skeletal muscle contraction during muscular dystrophy, myasthenia gravis.
involved in many physiological
processes – activates the release
mediators, hormones. Performs the function
pacemakers of the heart, stomach, etc.
Calcium as Calcium Phosphorus
salts is the basis of the skeleton, is included
in the composition of hydroxyapatite hard tissues
have anti-allergic effect
exudative reactions and decreased
vascular permeability; regulate
secretion of hormone and calcitonin;
participate in blood coagulation.
The price of potassium preparations and how to buy them
Price when buying online, rubles
Price on a pharmacy shelf, rubles
20 pcs. 500 mg manufacturer Avva
20 pcs. 500 mg manufacturer Akrikhin
If you want to buy potassium preparations, but do not know where it is better to do this, please contact our company. We offer a large selection of drugs – dietary supplements, vitamins, mineral complexes, we guarantee their high quality, which is confirmed by numerous certificates. All drugs have a carefully selected composition, where the active elements are contained in the optimal dose.
You can buy potassium preparations in our company in any way convenient for you: • through the site. To do this, it is enough to register on the resource, view the proposed catalog, and determine the suitable product. After sending it to the basket, it remains to fill out a small application, make payment, order delivery;
• by phone. Checkout is carried out online with the help of our manager. You will need to answer questions from a company representative by devoting only a few minutes of personal time to this procedure • in the store. Here you can personally familiarize yourself with the product range, as well as get detailed advice from our specialist on the topic of choosing the most suitable drug. After payment, the goods can be picked up immediately, having received it on hand.
In order to make cooperation as convenient and efficient as possible, we offer you several payment methods, among which you can choose the most suitable: • in cash upon receipt of products; • cash on delivery at the delivery service department; • bank transfer, which is easy to make through the terminal or any bank branch.
Delivery is carried out as soon as possible, will be carried out by your chosen method. You will see detailed conditions for the provision of the service in the corresponding section of our website, and you can also find out by phoning with the company manager. The contact phone number on which free calls are made during the working day is indicated on the pages of the site.
Having decided to buy potassium preparations from us, you make the right choice, get the opportunity to make a profitable purchase. For wholesale buyers, we have special offers, and retail sales are often carried out on current promotions, which also allows saving without compromising the quality of the goods. We work for you, and thank you for your trust!
Prevention and treatment of hypokalemia of various origins, including caused by various conditions and diseases (vomiting, diarrhea) and due to drug therapy (diuretics, glucocorticosteroids, cardiac glycosides).
Do not use after the expiry date printed on the package.
Synonyms of nosological groups
|Heading ICD-10||ICD-10 disease synonyms|
|E87.6 Hypokalemia||Hypokalemia Arrhythmia|
|Hypokalemic neuromuscular disorders|
|Hypokalemia in ketoacidosis|
|Hypokalemia in the treatment of saluretics|
|Potassium loss during saluretic therapy|
Attention! The information presented in the article is for guidance only. Materials of the article do not call for independent treatment. Only a qualified doctor can make a diagnosis and give recommendations for treatment based on the individual characteristics of a particular patient.