Suprax or amoxiclav which is better and what is the difference (differences in formulations,

Broad-spectrum antibiotics are objectively more practical for use than drugs with a narrow focus.

Having in stock only one type of antibiotic, many diseases can be cured, which is financially more profitable.

The spectrum of action of drugs of various pharmacological groups often echoes each other, but there are always significant differences. Based on these differences, a more suitable drug is selected.

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Sumamed

The active substance of the drug sumamed is azithromycin, which formally belongs to the group of macrolides. It differs from typical representatives of this pharmacological group by belonging to a subgroup of azalides, being the first representative of this subclass.

The drug has various forms of release, which allows you to choose the method of application that is most suitable for a particular disease. Sumamed can be purchased in the form of tablets with different dosages: 125 and 500 mg. This makes it possible to use it for the treatment of patients of different age groups, since mechanical division of the tablet is unacceptable.

New manufacturers are constantly appearing on the pharmaceutical market, so recently it has become possible to purchase tablets with a concentration of 250 and 1000 mg, as well as capsules with different concentrations of the active substance. Sumamed has the form of a solution for intravenous injection, powder, and even a ready-made suspension.

The drug is inactive or completely helpless against gram-positive bacteria that are resistant to the main representative of macrolides – erythromycin.

Frequently encountered side effects are those whose frequency reaches 10% or more. For sumamed, these side effects are dyspeptic disorders.

First of all, it is diarrhea, which occurs in more than 10% of cases. A side effect is associated with a violation of the intestinal balance of bacteria, which leads to impaired stool.

Slightly less common are nausea, vomiting, and pain in the abdomen.

The drug is contraindicated for the treatment of children under 3 years of age, and in the case of pregnant women only when the risk to the mother outweighs the risk to the child. During breastfeeding, it is recommended to suspend it for the duration of treatment.

Sumamed can not be used in conjunction with erythromycin due to the mutual enhancement of side effects, as well as if there is a history of intolerance to other drugs of the macrolide group. Contraindicated in patients with phenylketonuria, renal and hepatic insufficiency.

The main active ingredient is ampicillin, which belongs to the group of the most common antibiotics – penicillins.

This occurs due to a specific enzyme – betalactamase, which destroys the antibiotic.

The new generation of penicillins, to which amoxiclav belongs, has in its composition a second active substance – a beta-lactamase inhibitor. In the case of this drug, the inhibitor is clavulanic acid, which allows the use of an antibiotic even against those bacteria that have the ability to destroy it.

The drug is available in various forms, as well as with a different ratio of the concentration of ampicillin and clavulanic acid. Basically, these are three forms of release: tablets, powder for the preparation of solutions and powder for the preparation of suspensions.

Amoxiclav prevents the formation of a bacterial cell wall, as a result of which its destruction occurs over time, that is, the drug has a bactericidal effect.

A frequent side effect is dyspepsia, which is manifested by nausea, vomiting, diarrhea, and on the part of the blood system anemia, thrombocytopenia, as well as a decrease in the number of other formed elements.

Similarities and differences

Although the drugs are representatives of different pharmacological groups, they have very similar side effects and contraindications. These include phenylketonuria, liver failure. Both drugs affect the blood and digestive systems, so in the case of pathology of these systems, choosing the right one also fails.

The advantage of Sumamed over Amoxiclav is its use in children older than 3 years, which makes it more popular in pediatric practice. Regarding pregnancy and lactation, the drugs have similar indications.

Application area

The main difference between Sumamed and Amoxiclav is in their scope.

Sumamed is an indispensable drug in the treatment of chlamydial infection. This can be a disease of the lower parts of the genitourinary system, pelvic organs, as well as chlamydia of unspecified localization. The drug is a means of choice for pregnant chlamydia. Often it is used in the treatment of Lyme disease.

Amoxiclav is widely used in gynecological practice for the treatment of inflammatory diseases of various etiologies. It is also used to treat soft tissue infections.

Which is better and more effective – Sumamed or Amoxiclav

“Sumamed and Amoxiclav, as far as I know, are widely used to treat bacterial infections of various organs and systems. They have proven themselves well for a long time.

But what interests me most is what is prescribed primarily for tonsillitis – Sumamed or Amoxiclav? What is the difference between these antibacterial drugs? Why, for certain pathologies, different doctors give preference to Amoxiclav, and for others, to Sumamed? ”

Sumamed and Amoxiclav belong to different groups of antibacterial drugs and there are many differences between them. The active substance of Sumamed is azithromycin – an antibiotic from a number of macrolides.

This drug has a pronounced bacteriostatic effect, which is realized by inhibiting protein synthesis in the cells of microorganisms. This leads to the impossibility of their further reproduction and makes them more sensitive to the protective immune mechanisms of the body.

Amoxiclav consists of the penicillin antibiotic amoxicillin and the clavulanic acid penicillinase inhibitor. This combined bacterial agent has a bactericidal effect on germs.

Amoxicillin is able to disrupt the integrity of the cell membranes of pathogenic flora, which leads to their death. Clavulanic acid protects the antibiotic from the protective mechanism of many bacteria – the synthesis of special enzymes that break down amoxicillin.

Patients often confuse Sumamed and Amoxiclav because of the similar names of the active substances, and also because they are prescribed for the same pathologies.

The list of indications for Amoxiclav and Sumamed is largely similar, but it has a number of significant differences. They are due to the fact that azithromycin preparations are more selective for certain types of tissue in which they accumulate. Therefore, Sumamed is mainly used in pathologies of the following tissues and organ systems:

  • respiratory tract (bronchitis, pneumonia, laryngitis, pleurisy);
  • ENT organs (sinusitis, otitis media, pharyngitis, tonsillitis);
  • skin (erysipelas, erythema migrans);
  • genitourinary system (chlamydia).

Amoxiclav, due to its lower selectivity for the penetration of amoxicillin and accumulation in the tissues of the body, creates a therapeutic concentration in a large number of organs. Therefore, this antibiotic has a wider scope of use. It can, in addition to the above pathologies, be used for bacterial pathologies:

  • in dental practice;
  • internal female genital organs (vagina, uterus, fallopian tubes, ovaries);
  • gall bladder and bile ducts (cholecystitis, cholangitis);
  • digestive system (gastritis, duodenitis, enteritis, colitis);
  • soft, connective tissue and musculoskeletal system.

This is due to the pharmacological characteristics of the metabolism of antibiotics. Sumamed has the ability to accumulate in the peripheral tissues of the body. It also passes into the focus of inflammation, where its concentration may be 10-30 times the amount of azithromycin in peripheral blood.

After the last dose of the drug, its therapeutic dose remains in the tissues for about 72 hours.

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Usually, the duration of treatment with Sumamed is 2-3 days shorter than with Amoxiclav.

It is definitely impossible to say which is better – Sumamed or Amoksiklav. It all depends on the type and strain of the bacterial infection that has infected the patient. However, for about 20 years, extensive research has been conducted on the issue of antibiotic resistance of bacteria to these drugs.

In recent years, there has been an increase in the frequency of strains of microorganisms that have become invulnerable to the penicillin series of antibiotics.

Resistance to macrolides remains at a relatively low level, which allows them to be actively prescribed if necessary in a stationary or outpatient practice.

When taking which of these two drugs, side effects are less likely to occur? First, it should be noted that both Sumamed and Amoxiclav belong to the group of antibiotics, when taken, severe side effects develop relatively infrequently with damage to important systems of the patient’s body.

Both drugs are characterized by the development in a fairly large part of patients with dyspeptic symptoms (a feeling of heaviness in the abdomen, nausea, vomiting, diarrhea) during therapy.

It is also possible to attach superinfection, especially against the background of prolonged use of antibiotics.

Since Amoxiclav is a beta-latcine antibacterial agent, a fairly significant part of the population (5-7%) has hypersensitivity to it.

Sometimes there is also a toxic effect of amoxicillin on the central nervous system with the development of headache, dizziness, parasthesia.

A wider range of possible side effects when taking Sumamed, but at the same time, they occur sporadically. Since it undergoes metabolism in the liver, it cannot be used in chronic inflammatory and oncological pathologies of this organ. This can lead to the development of chronic functional liver failure.

Sumamed also has the ability to lengthen ventricular repolarization, which sometimes leads to the development of cardiac tachyarrhythmias and impaired normal rhythm. Therefore, the drug can not be prescribed with indirect signs of a tendency to this complication (lengthening of the QT interval on the electrocardiogram).

The most serious side effect that may occur when taking Sumamed is a violation of the kidneys. It has been proven in clinical experiments that the drug reduces the glomerular filtration rate, which leads to an increase in the concentration of creatinine, urea in blood plasma.

In most cases, these changes are reversible and pass after the end of therapy, but sometimes they turn into interstitial nephritis.

Thus, side effects are less common when taking Sumamed. But if the patient does not have hypersensitivity to beta-lactam antibiotics, then it is safer to prescribe Amoxiclav.

The answer is yes – yes, you can. An allergy to Amoxiclav is caused by hypersensitivity to the beta-lactam compound. The latter include penicillins, cephalosporins, monobactams and carbapenems. If there is a history of allergic reactions to any of the drugs in these groups, it is necessary to prescribe another antibiotic with a completely different molecular structure.

This is especially important for children with allergic diathesis and a tendency to develop Quincke edema and anaphylactic shock.

According to current recommendations for the treatment of bacterial pathologies, macrolides are the drugs of choice in this situation. They have absolutely no cross-reactions with penicillins, which makes Sumamed a safe treatment option for patients with allergies to Amoxiclav.

During pregnancy and lactation, it is recommended to prescribe Amoxiclav. This is primarily due to the lower teratogenic effect that all penicillin antibacterial drugs possess.

The American FDA gave Amoxiclav category B, which indicates that this drug can be taken during pregnancy and that there is no evidence of toxic effects on the fetus.

Therefore, this drug must be prescribed in situations during pregnancy, when the potential benefits of the appointment significantly exceed the harm.

Both Sumamed and Amoxiclav are safe drugs for children of any age, starting from the first month of life. They are recommended for use in pediatric practice by the world’s leading specialized associations of doctors.

Long-term use of drugs showed that the incidence of side effects in children does not differ significantly from adults. However, before the first use of Amoxiclav it is recommended to conduct a test for hypersensitivity to the drug.

Especially for children, manufacturing companies produce an antibiotic in the form of a syrup. This helps to accurately dose the required amount of the drug, depending on the age and body weight of the child.

Antibiotics are classified as systemic drugs that act on various systems in the patient’s body. Therefore, you can not self-medicate and take Amoxiclav or Sumamed without the appointment of a qualified doctor.

As practice shows, ignoring this simple rule often leads to the development of complications, side effects and the lack of clinical effect from taking the medication.

Another negative effect is the appearance of antibiotic-resistant strains of bacteria, for the treatment of which other groups of drugs must already be used.

It is necessary to take an antibiotic at the same time of the day to ensure a sufficient concentration in the blood. If you miss an admission, you need to take a dose of the drug as quickly as possible, and then continue the course of therapy as usual.

You can drink a tablet or syrup of the drug only with plain water. You can’t use soda, dairy products, coffee or strong tea for this purpose, since they can change the absorption and metabolism of the antibiotic, which is negatively displayed on the treatment results.

The difference between Suprax and Amoxiclav

Sumamed or Amoxiclav are broad-spectrum antibacterial agents that are active against gram-positive and gram-negative microorganisms. They are prescribed empirically or after studying the sensitivity of the pathogen to these antibiotics.

Belongs to inhibitor-protected semi-synthetic antibacterial beta-lactam preparations. It consists of the penicillin antibiotic amoxicillin and clavulanic acid, an inhibitor of the microbial enzymes beta-lactamases.

Sumamed or Amoxiclav are broad-spectrum antibacterial agents that are active against gram-positive and gram-negative microorganisms.

Amoxiclav exhibits a bactericidal effect, inhibiting the synthesis of components of the cell wall of the microorganism. Peptidoglycan ceases to be created, which leads to the death of bacteria. Clavulanic acid protects amoxicillin from destruction by beta-lactamase enzymes, expands the spectrum of antibiotic action.

Amoxiclav affects both gram-positive and gram-negative microorganisms. Kills streptococci (including verdant), staphylococci (including

golden), Corynebacterium – diphtheria bacillus, spore-forming hay bacillus, anthrax causative agent. Active against enterococci, enterobacter, listeria, nocardia, pathogenic Escherichia coli, Pfeiffer coli.

It acts on the main pathogens of intestinal infections – dysentery bacillus, salmonella, yersinia, cholera vibrio.

Amoxiclav is used to treat peptic ulcer, ENT infections, enterococcal cystitis, odontogenic infections, bronchitis, pneumonia caused by hemophilic bacillus, cholecystitis, peritonitis, Lyme disease, osteomyelitis.

Pharmacokinetics

Oral bioavailability is 70%, maximum when using the drug at the beginning of a meal. Fully absorbed in the intestines. The maximum concentration is achieved one hour after administration. Communication with plasma proteins is 18-25%.

Both active substances are well distributed on hard and soft tissues. Penetrate through the blood-brain barrier in inflamed meninges (with meningitis), in the placenta and breast milk.

An antibiotic with an inhibitor is excreted mainly by the kidneys by 60% unchanged. 10% of amoxicillin leaves the body in the form of a metabolite – penicilloic acid. Clavulanic acid is excreted both unchanged and in the form of an inactive metabolite through the kidneys and intestines.

Side effects: nausea, vomiting, bile reflux, diarrhea, flatulence, black tongue, liver failure, cholestasis, allergic rash, anaphylactic shock, Quincke’s edema, pseudomembranous colitis, a decrease in the number of leukocytes, platelets, interstitial nephritis.

Description of Sumamed

Bacteriostatic antibacterial drug of the macrolide class (azithromycin). It inhibits the formation of protein on the ribosomes of bacteria, inhibiting the reproduction and growth of pathogenic microorganisms. In large doses, kills them.

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It has an effect on gram-positive microorganisms – streptococci, staphylococci, bacteroids, clostridium perfringens, enterococci. Effective against gram-negative microbes – fusobacteria, the causative agent of gonorrhea, meningitis, borreliosis, against hemophilic bacillus and legionella. Penetrates into the cell, acting on chlamydia, mycoplasmas, ureaplasmas.

It is prescribed for infectious and inflammatory processes of the genital area (prostatitis, urethritis, endometritis, vaginitis), Reiter’s syndrome, mycoplasma pneumonia.

Amoxiclav is an antibacterial drug that shows a bactericidal effect, because azithromycin acts bacteriostatically. Penicillins do not act against mycobacteria, intracellular infections (mycoplasmas). Azithromycin is active against them. Amoxiclav can lead to the formation of wallless L-forms of bacteria and chronic infection.

Azithromycin maintains a therapeutic concentration much longer, so its administration lasts less.

With intolerance to Amoxiclav, it is replaced by azithromycin.

The price for 3 tablets of Sumamed at 500 mg is 382 rubles., Amoxiclav costs 243 rubles. for 15 tablets.

Azithromycin is a newer antibiotic, therefore, the spectrum of antimicrobial activity is much wider than that of inhibitor-protected penicillins, and includes mycoplasmas, chlamydia.

The effectiveness of the drug depends on the status of the patient.

For children

Azithromycin is preferable, since the duration of its use is much less than penicillins.

Azithromycin is preferred, but both antibiotics are used only when the risk of infection from the mother exceeds the risk to the fetus.

Amoxiclav is taken at the beginning of the meal, azithromycin is 1 hour before eating or 2 hours after it. Children under 6 years of age are recommended to take the suspension.

The course of treatment with Amoxiclav is up to 14 days, with azithromycin – about 5 days.

The dosage of drugs depends on the nature of the disease. Sometimes a single dose of Sumamed is prescribed in a dose of 1 g to an adult (with ureaplasmosis).

With bacterial vaginosis, mycoplasmosis, ureaplasmosis, I prescribe Sumamed patients. It is an effective antibiotic. I also prescribe immunostimulants – Galavit, Viferon.

Bogatikova A.D., pulmonologist

For the treatment of mycoplasma pneumonia, Sumamed is used in our department. Helps to quickly recover.

There was a burning sensation when urinating, many infections were found. Prescribed medicine Sumamed. Side effects appeared – diarrhea, bloating. I had to take Bifidumbacterin. But he coped with infections.

Suprax or Amoxiclav are used to treat bacterial diseases. Both drugs have a wide spectrum of antimicrobial activity and quickly relieve the manifestations of the disease. When used correctly, they do not cause side effects.

Suprax or Amoxiclav are used to treat bacterial diseases.

Suprax

Release form: tablets with 0,2 or 0,4 g of the active substance – cefixime. Auxiliary components: colloidal silicon dioxide, magnesium stearate, carboxymethyl cellulose, azorubine. The shell contains titanium dioxide, dyes, gelatin.

Another form is granules for suspension for internal use, 5 ml contains 100 mg of cefixime. The composition is supplemented with sodium benzoate, a yellow resin, a strawberry flavor.

The drug inhibits the synthesis of the bacterial cell membrane. Resistant to beta-lactamase. Active against many bacteria that cause the pathological process. Some strains of streptococci, pseudomonads, listeria, staphylococci, enterobacteria are resistant to the drug.

When taken orally, the bioavailability of the drug is 40-50%, regardless of the meal. The greatest amount of active substance in the blood serum is observed 4 hours after application. 65% of the drug binds to blood proteins.

The half-life of this drug is from 3 to 4 hours. In patients with impaired renal excretory function, this time is slightly increased.

  • pathology of ENT organs – pharyngitis, sinusitis or tonsillitis;
  • bronchitis – acute and without complications;
  • middle ear inflammation;
  • urinary tract infection uncomplicated;
  • uncomplicated gonorrhea.

Suprax is contraindicated in case of hypersensitivity to cephalosporin and penicillin antibiotics. This antibiotic is used with caution:

  • with chronic kidney failure;
  • in old age;
  • in the presence of a history of pseudomembranous colitis;
  • in children under 6 months.

The use of Suprax during pregnancy is limited. It is permitted only in cases where the benefits of its use are higher than the potential risk. If the medicine must be taken during breastfeeding, then the child is prescribed artificial nutrition during the therapeutic course.

The use of Suprax during pregnancy is limited.

Suprax sometimes causes allergic reactions in the form of itching, fever and eosinophils in the blood, and skin hyperemia. Other side effects:

  • feeling of dry mouth;
  • decreased appetite;
  • nausea;
  • diarrhea;
  • an increase in the amount of intestinal gas;
  • intestinal microflora imbalance;
  • changes in the activity of liver enzymes;
  • digestive tract candidiasis;
  • inflammation of the oral mucosa, tongue;
  • inflammation of the colon mucosa.

An overdose increases the risk of adverse reactions. Symptomatic therapy is needed to treat these symptoms.

Amoxiclav

Active substances of Amoxiclav – amoxicillin trihydrate, potassium salt of clavulanic acid.

Auxiliary components include: colloidal silicon dioxide, croscarmellose sodium, crospovidone, talc, magnesium stearate, microcrystalline cellulose. Amoxiclav is produced in tablet form.

The tablet contains 250, 500, 875 mg of amoxicillin. The concentration of clavulanic acid in each of the tablet options is the same and is 125 mg.

The combination of amoxicillin with clavulanic acid makes the drug more effective, as it is effective in combating most gram-positive and gram-negative bacteria. The drug also acts on microorganisms resistant to penicillin antibiotics, does not allow the development of tolerance.

Amoxiclav resistant microbes:

  • enterobacteria;
  • pseudomonads;
  • chlamydia
  • mycoplasmas;
  • legionella;
  • yersinia.

All components of Amoxiclav penetrate into the blood and are distributed in tissues and liquid medium. Therefore, it is more versatile. Active substances do not enter the blood-brain barrier. They cross the placenta into the blood of the fetus developing in the womb and, to a small extent, breast milk.

Most often, Amoxiclav is used to treat acute respiratory diseases.

Augmentin

Antibiotics have a wide spectrum of action and are used to treat inflammatory processes, sexually transmitted diseases, various infections.

Such drugs as Augmentin or Amoxiclav belong to the penicillin group and contain clavulanic acid.

The therapeutic properties of these funds are almost identical, but they also have some differences that are important to consider when choosing.

Antibiotics Augmentin and Amoxiclav are used to treat inflammatory processes.

“What is better Augmentin or Amoxiclav?” – this is a question often asked by people who are faced with taking antibiotics based on amoxicillin. This substance is contained in both one and another drug.

They also include an auxiliary component – the potassium salt of clavulanic acid, which is a beta-lactamase inhibitor. Thanks to this substance, the effect of the antibiotic is enhanced.

By their properties, both drugs are identical and have slight differences.

Historical summary

More than 80 years have passed since the discovery of antibiotics. During this period, they saved the lives of millions of people. Medicines were used in the treatment of inflammatory and infectious diseases caused by various kinds of microorganisms. Over time, some bacteria became resistant to antibiotics, so scientists were forced to look for options that could make a difference.

In 1981, in the UK, a new generation of antibiotics was introduced that combined amoxicillin and clavulanic acid. The results of the studies proved the high effectiveness of the drug, and this combination became known as the “protected antibiotic”. After 3 years, after the UK, the tool began to be used in the United States.

The drug has a wide spectrum of action, so it has become popular in many countries of the world. It is used in the treatment of respiratory diseases, inflammatory processes of the genitourinary system, postoperative infections, and also sexually transmitted diseases.

The most popular drugs of the penicillin group are Amoxiclav and Augmentin. But there are other analogs that contain in their composition the active substance – amoxicillin:

  • Flemoxin Salutab;
  • Amosin;
  • Sumamed;
  • Amoxicillin;
  • Azithromycin;
  • Suprax and others.
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The difference between Amoxiclav and Augmentin is insignificant, but still it is. To figure out which drug is better, you need to study the features of each of them.

The drug belongs to new types of antibacterial agents of the penicillin group, which are effective in combating various pathogenic microflora, such as:

  • streptococcal and staphylococcal infections;
  • enterococci;
  • listeria;
  • pathogens of brucellosis;
  • Salmonella and many others.

Augmentin and Amoxiclav are penicillin-type antibiotics. According to their healing properties, they are identical, but there are differences between them.

The drugs suppress the vital activity of microbes, do not allow them to multiply and create an unfavorable environment for bacteria.

Choosing which is better – Amoxiclav or Augmentin, the doctor takes into account various factors: the duration of the disease, the characteristics of the patient’s body, the presence of contraindications.

When using drugs such as amoxiclav or augmentin for bronchitis, you should familiarize yourself with the indications and contraindications for use.

The drug consists of amoxicillin. It is an antibiotic of the penicillin series and clavulanic acid, which, preventing the destruction of amoxicillin, makes the drug more resistant. With a wide spectrum of action, amoxiclav affects gram-positive and gram-negative aerobic bacteria, as well as anaerobic bacteria.

After taking amoxicillin in combination with clavulanic acid, it is rapidly absorbed and after an hour reaches the maximum content in the patient’s blood. Thus, the drug penetrates the lungs at high speed due to the high penetration rate of the drug components into the blood plasma. The effect of treatment becomes apparent on the second or third day from the start of use.

In the pharmacy you can buy the drug amoxiclav with bronchitis from 91.20 rubles. It is prescribed for pulmonary infections caused by microorganisms that are sensitive to the drug: echinococcus, streptococcus, shigella, moraxella, listeria, protea, bordetella, gardnerella, klebsiella. In the absence of amoxiclav, its inexpensive analogue, augmentin for bronchitis, is successfully used, the cost is from 126.00 rubles.

  • Tablets 500 and 250 mg of amoxacillin and 125 mg of clavulanic acid. Designed for patients weighing more than 40 kilograms. The daily dose is prescribed by the attending physician and depends on the severity of the disease. Dosage can be 375 or 625 mg per day at regular intervals. When taking, it is recommended to dissolve the tablets in half a glass of water. Amoxil-K analog is prescribed for bronchitis, the price is 30 hryvnias. Tablets with a similar composition called flemoklav solutab are also available, effective for bronchitis, price from 206.50 rubles.
  • Amoxiclav 2X tablets. Dosage 1000 mg, prescribed for adults with complicated infections of the upper respiratory tract, 1 tablet twice a day.
  • Powder for suspensions. One vial contains 125 mg of amoxicillin and 31,25 milligrams of clavulanic acid. Children are prescribed from 3 months, the dose for children is 30 mg per kilogram of weight, it is calculated by the doctor based on the patient’s body weight. The powder in the bottle is shaken and 86 milliliters of water are added to it, after which it is again thoroughly shaken until a homogeneous suspension appears. Take with a measuring spoon three times a day.
  • Powder for injection. Two types of dosage: 500 mg of amoxicillin plus 100 mg of clavulanic acid and 1 g of amoxicillin plus 200 mg of clavulanic acid. The dosage is selected by the doctor depending on the age and weight of the patient. The drug is diluted with water for injection, used for intravenous administration.

Important! To reduce side effects from the digestive organs, the drug is best taken with food. Throughout the course, it is recommended to drink more fluid.

Allergy to penicillin, clavulanic acid. Violation of the liver, cholestatic jaundice. In diseases of the kidneys and gastrointestinal tract, the drug is used with caution under the supervision of a doctor. During pregnancy and during the period of feeding the baby, amoxiclav is prescribed with the simultaneous administration of anticoagulants and strictly according to indications.

Side effects may include gastrointestinal problems: nausea, temporary loss of appetite, sometimes vomiting and pain in the stomach. From the skin – allergic rashes. From the nervous system: headache attacks, anxiety, sleep disturbances.

With proper and timely use of the drug, side effects can be minimized. The course of treatment with amoxiclav can be up to 14 days. The minimum course is 7 days. The effect of intravenous administration is achieved faster, and after improvement of the patient’s condition, treatment is continued with tablets.

Amoxiclav and Suprax are antibacterial drugs that can have the same bactericidal effect. Active components block peptidoglycan, which is the main building block of a bacterial cell wall.

Amoxiclav and Suprax are antibacterial drugs that can have the same bactericidal effect.

The active ingredient of Suprax is cefixime, which refers to cephalosporins of 3 generations. The drug is in the form of dispersible tablets.

Additional components used in the composition of the drug are:

  • Povidone;
  • hyprolosis;
  • colloidal silicon dioxide;
  • magnesium stearate;
  • calcium trisesquihydrate saccharinate;
  • cellulose;
  • dye yellow sunny sunset;
  • strawberry flavoring.

An antibiotic is a semi-synthetic compound. It has the ability to quickly and easily absorbed in the gastrointestinal tract. The medication is active in relation to gram-negative and gram-positive representatives of pathogenic microflora.

In accordance with the instructions for use, the drug is prescribed for the treatment of:

  • respiratory tract infections – sinusitis, acute and chronic pharyngitis, tonsillitis agranulocytic, acute bronchitis, tonsillitis;
  • otitis media;
  • urinary tract infections;
  • shigellosis;
  • uncomplicated gonorrhea of ​​the cervix, urethra.

Contraindications to use is the presence of an allergy in the patient to the components of the pharmaceutical agent.

Do not use the medication to treat people with kidney failure and colitis. The use of the drug for therapy in the presence of pregnancy and in old age is not recommended.

When conducting antibiotic therapy in a patient, the following side effects may occur:

  • skin itching, urticaria;
  • drug fever;
  • headache, tinnitus, dizziness;
  • trobmocytopenia, bleeding, angranulocytosis;
  • abdominal pain, digestive disorders, constipation, nausea, vomiting;
  • impaired renal function, jade.

Suprax is prescribed for sinusitis, acute and chronic pharyngitis, tonsillitis agranulocytic, acute bronchitis, tonsillitis.

Before using the product, you should always consult your doctor and conduct therapy in accordance with his recommendations.

If the daily dose is exceeded, the patient may develop signs of an overdose, which are characterized by increased manifestations of side effects.

To eliminate the consequences, symptomatic therapy, a gastric lavage procedure, the use of antihistamines and glucocorticoids are used.

The implementation of the drug is carried out in a pharmacy after presenting a prescription to the attending physician. The drug can be stored for 3 years at a temperature not exceeding 25 ° C in a dark and dry place.

In the treatment of bacterial infections of various organs, cephalosporin group antibiotics are often used, among which Suprax or Suprax Solutab are popular. What is the difference between these drugs and which one will be more effective in a particular case, should be determined before choosing a remedy.

In the treatment of bacterial infections of various organs, cephalosporin group antibiotics – Suprax or Suprax Solutab are used.

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Tatyana Jakowenko

Editor-in-chief of the Detonic online magazine, cardiologist Yakovenko-Plahotnaya Tatyana. Author of more than 950 scientific articles, including in foreign medical journals. He has been working as a cardiologist in a clinical hospital for over 12 years. He owns modern methods of diagnosis and treatment of cardiovascular diseases and implements them in his professional activities. For example, it uses methods of resuscitation of the heart, decoding of ECG, functional tests, cyclic ergometry and knows echocardiography very well.

For 10 years, she has been an active participant in numerous medical symposia and workshops for doctors - families, therapists and cardiologists. He has many publications on a healthy lifestyle, diagnosis and treatment of heart and vascular diseases.

He regularly monitors new publications of European and American cardiology journals, writes scientific articles, prepares reports at scientific conferences and participates in European cardiology congresses.

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