Medications for improving cerebral circulation

Vasodilator is a group of drugs with various mechanisms of action. Their main drawback is the indiscriminate action, due to which they expand not only the arteries of the brain, but also other blood vessels, often giving a drop in blood pressure, at which the cerebral blood flow worsens even more.

This point is especially unpleasant for the elderly, whose arteries are severely affected by atherosclerosis. Orthostatic hypotension (darkening in the eyes with a sharp rise) and the risks of developing ischemic strokes can often occur in patients with vasodilators.

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Antispasmodics

Antispasmodics relaxing the smooth muscles of the vascular wall, expand the lumen of the vessels. These are the most mild and relatively safe drugs, they include tablet and injection:

  • No-spa (60 tab. 220 rubles)
  • Drotaverine hydrochloride (100 tab. 50 rubles)

The drugs do not work well on vessels affected by atherosclerosis. They can also rob the diseased areas of the brain, redistributing blood flow in favor of healthy areas due to the better preservation of blood vessels there. Therefore, this group of drugs is not widely used in elderly patients, for whom drugs of the following class are preferred.

By blocking calcium channels, the cerebral vessels do not expand to the detriment of the rest of the blood circulation. Microcirculation is predominantly improved. The main side effect of these drugs is a drop in blood pressure.

These include: Adalat, Kordafen, Brainal, Norax, Arifon, Grindek, Diacordin, Cordaflex, Diacordin, Cortiazem, Latsipil, Logimaks, Nafadil, Nemotan, Nimotop, Plendil, Stamlo, Foridon, Cinnarizin, Tsinedil, Tsifnard.

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Nimodipine (Nimotop)

Application: Nimodipine is used for the prevention and treatment of various disorders of the blood supply to the brain. Nimodipine is available in 30 milligram tablets. One package contains twenty, fifty or one hundred tablets. It can also be purchased in the form of a 0,02% solution for infusion (in plastic packaging or bottles of 50 milliliters).

  • Nimodipine is treated after hemorrhage under the meninges, as well as with strokes for five to fourteen days.
  • For prevention, the drug is prescribed in tablet form, two tablets every four hours, a total of three hundred and sixty milligrams per day.
  • For patients weighing less than seventy kilograms and unstable blood pressure, the drug begins to be administered in a reduced dose (for example, from half a milligram).

Side effects: the risk of side effects of the drug is higher with intravenous administration. Pressure may drop sharply. When taking pills, digestive disorders in the form of nausea and diarrhea are not uncommon.
Contraindications: pregnancy and the simultaneous use of infusion and tablets of this drug. It is also necessary to be careful with intracranial hypertension, renal failure.
Price: 100 tablets 1100 rub.

Cinnarizine (Stugeron)

It is produced in 25 mg tablets (packs of 30 or 50 tablets); it is used for course administration (from three weeks to six months), 1-2 tablets three times a day. Indications and contraindications are similar to nimodipine. Today, the drug is heavily pressed by vinpocetine.
Price: Cinnarizine 50 pcs. 30-70 rub, Stugeron 50 pcs. 150-200 rub.

Vinpocetine (Cavinton)

This is a drug from plant materials (periwinkle). The drug combines the properties of a vasodilator and an agent that limits thrombosis. Vinpocetine is also able to improve metabolism in brain tissue and make it more resistant to oxygen starvation.
Application: 5 mg tablets are used once three times a day after meals. Solutions are administered intravenously. Before the end of treatment, the dose of the drug is gradually reduced until it is completely canceled.
Contraindications: not recommended for combined use with heparin (due to the risk of bleeding). Also, in severe forms of coronary heart disease and arrhythmias, parenteral administration of the drug is prohibited. Since the drug crosses the placenta and passes into breast milk, it is not recommended for pregnant and lactating women. Deprived of the phenomenon of “robbery.”
Vinpocetine analogs: Vero-Vinpocetine, Bravinton, Vincetin, Vinpoton, Telektol, Cavinton forte.
Price: Cavinton 5 mg. 50 pcs. 250 rub., Vinpocetine 5 mg. 50 pcs. 40-80 rubles., Korsavin 5 mg. 50 pcs. 70-90 rub.

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The largest international organization in evidence-based medicine – Cochrane International Cooperation does not recognize the effectiveness of Cavinton and does not include it in its Review, which allows us to talk about the proven effect of the drug. Since it was not conducted double blind placebo-controlled studies.

However, domestic neurologists and vascular surgeons repeatedly published the results of work with this drug (including improvement of cerebral circulation, confirmed by the results of brain tomography and angiography of blood vessels) and continue to uphold its position in the treatment of chronic cerebrovascular disorders of varying severity. Traditionally, the management programs for such patients include Cavinton’s course drip and courses of Vinpocetine tablets.

Alpha-adenoblockers simultaneously with the expansion of small vessels improve metabolism in the brain tissue, reduces platelet aggregation. They are indicated for acute and chronic metabolic disturbances in the brain, including vascular dementia, transient oxygen starvation of the brain against a background of vascular spasm, as well as against the background of arterial hypertension or atherosclerosis.

  • Nicergoline – 5 ampoules of 4 mg. 250 rubles, 30 tablets 350-400 rubles.
  • Sermion – 30 mg tablets. 30 pcs 650 rubles, 5 mg each. 30 pcs 450 rub
  • Vazobral (alpha-dihydroergocriptine and caffeine)
  • Instenon (etofillin, etomivan, hexobendin), 30tab. 200-250 rub. 5 amp. 2 ml each. 250 rub

The treatment of blood vessels in the brain should be carried out immediately after the symptoms of the disorder are detected. The development of diseases often leads to bad consequences or death.

To alleviate the condition, the following types of drugs are used:

  • Anticoagulants.
  • Vasodilator drugs.
  • Nootropic.

Only a specialist should examine sick people and determine the appropriate therapeutic technique. Self-medication for problems with the vessels of the head leads to serious consequences.

If suspicious symptoms are found, it is recommended to immediately consult a specialist in this profile.

After the examination, the doctor prescribes medications that improve cerebral circulation, which increases its oxygenation and trophism. This will maintain the state of the brain at the right level.

The most common groups of such drugs are:

  1. Vasodilators.
  2. Anticoagulants and antiplatelet agents.
  3. Nootropics.
  4. Some vitamins.

It must be remembered that self-administration of treatment may be ineffective, which will only lead to a worsening of the patient’s condition. Therefore, it is recommended to immediately seek medical attention from a specialist. Neuropathologists can draw up an effective treatment regimen consisting of one or more groups of drugs.

Vasodilators

Increased blood flow, improved oxygenation and nutrition of brain cells occurs due to the expansion of the lumen of arterial vessels. This allows you to increase the volume of blood entering the brain. Such an action can prevent the development of a state of hypoxia, as well as nutritional deficiencies.

This group of vasodilator drugs includes:

  • Calcium antagonists – vasodilation occurs by reducing the amount of calcium received inside the smooth muscle cell. Thus, the ion pump is disrupted and the muscle relaxes, which leads to dilatation of the vessel. You need to be careful and use such drugs only under the supervision of a specialist, since calcium antagonists have a systemic effect. The most common representatives: Nifedipine, Diazepam, Finoptin, Odalat, Verapamil.
  • Adrenergic blockers – representatives of this group block the conduction of nerve impulses to the smooth muscles of the vessel, which leads to a sharp increase in the lumen of the vessel. A feature of adrenergic blockers is the ability to expand not only arterioles, but also large veins. This contributes to an effective reduction in blood pressure, which helps to combat hypertension. Common representatives of vasodilators: Sermion, Prazosin, Kardura, Celiprol.

Vascular drugs to improve blood circulation can increase blood flow to the brain tissue, improve the blood supply process. The pharmacological action allows you to cope with oxygen starvation, a lack of nutritional components.

Calcium antagonists

This category of drugs has long been used to stabilize cerebral circulation. In the modern industry of pharmacology, the 3rd generation of these drugs is manufactured. Calcium antagonists increase the diameter of the artery, do not change the tone of the venous vessels. After their components enter the body, cerebral blood flow is stimulated, many micronutrients enter the body.

Calcium antagonists are divided into the following subcategories: Dihydropyridines, Phenylalkylamines, Benzothiazapines. After the development of drugs of the 2nd generation, their list is expanding.

Anticoagulants

Antiplatelet agents and anticoagulants effectively help get rid of transient ischemic attacks, reduce the risk of ischemic stroke, and prevent the formation of blood clots and emboli.

The presented drugs that improve cerebral circulation by diluting blood are used only after passing all laboratory tests, as well as studying data on possible contraindications.

Using these funds, it is necessary to periodically donate blood for the study of coagulogram and biochemical properties.

The most common anticoagulants include: Warfarin, Fraxiparin, Kleksan, Fragmin.

Representatives of antiplatelet agents are: Aspirin, Curantil, Pentoxifylline, Ticlopidine.

These drugs increase blood flow. Drugs help normalize cerebral circulation. They are allowed for use with a high probability of ischemia. The most effective drugs are: Aspirin, Curantil, Warfarin, Heparin.

Herbal preparations

These drugs are used to treat circulatory problems of the brain, have a small number of contraindications, and are used for preventive purposes. Some are sold over the counter, drunk according to the instructions.

Pills for improving cerebral circulation of plant origin are most often made on the basis of the following medicinal plants:

The healing components of these plants are able to have a relaxing effect on the vessels of the brain. Which leads to the influx of large volumes of blood, better oxygenation and nutrition of the brain.

Comprehensively affect the brain and its vessels. First of all, the alkaloids of this plant eliminate the spasm of the smooth muscles of the blood vessels of the brain, this increases the microcirculation, increases the permeability of the vascular wall. Such an effect helps to eliminate swelling of the brain, protect the walls of blood vessels and nerve cells from the action of external negative factors.

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Ginkgo biloba preparations include:

  • Babylon;
  • Ginkor Fort;
  • Ginkoum;
  • Gingium;
  • Ginkgo Biloba C;
  • Tanakan;
  • Doppelherz Ginkgo Biloba.

The useful substances of this plant are able to stop the spasm of arterial vessels, stimulate energy processes in neurons, increase the conductivity of nerve impulses, improve the rheological properties of blood, increase blood flow to the brain.

Periwinkle preparations are:

  • Vero-Vinpocetine;
  • Cavinton;
  • Vinpocetine;
  • Bravinton;
  • Telektol.

Self-administration and use of these drugs that improve cerebral circulation is not recommended. Such actions can lead to a deterioration in the general condition of the body. Before starting treatment, you must consult a specialist who will conduct all the necessary studies and prescribe the most effective treatment.

Nootropic drugs

This group of drugs has a bracing effect on brain tissue, and, if necessary, can increase blood flow. Nootropics contribute to the improvement of metabolic processes in neurons, and they also strengthen their connections. This leads to increased resistance of cells of the central nervous system to the effects of external destructive factors and hypoxia. That allows you to maintain their normal performance for a long time in adverse conditions.

The following drugs belong to nootropics:

  • Pantogam;
  • Glutamic acid;
  • Piracetam;
  • Phenotropil;
  • Cerebrolysin;
  • Actovegin;
  • Microgridin.

Some drugs are taken with excessive psychomotor irritability, irritability, and insomnia.

Nootropics also have a psychostimulating effect and will be useful for chronic fatigue, a constant feeling of drowsiness, mental and physical overwork. Nootropics with such a mechanism of action are able to dilate blood vessels, which is why they were attributed to drugs that improve cerebral circulation.

Blood circulation stimulation for cervical osteochondrosis

Stabilization of the blood circulation of the brain during the development of cervical osteochondrosis is not an easy task. The main problem is that the disease has recently been diagnosed in people at the age of 25. All problems are associated with the constant sitting in front of the computer in an anatomically incorrect position.

Cervical osteochondrosis causes problems with the main blood vessels in this area, vertebral artery syndrome appears. In this situation, drugs to stimulate blood supply will not be enough. In this situation, other measures of influence on this part of the spine are required. Doctors advise wearing a Shants collar in everyday life, performing simple exercises that stimulate blood flow.

  • Lower your head so that the chin is in contact with the neck, then make turns in different directions 5 times.
  • Raise your head slightly, perform similar turns 5 times in each direction.
  • Make head tilts so that the ear touches the shoulder 5 times on each side.
  • Keep your head straight, fingers touch the back of the head. The back of the head must be pressed in the palm of your hand for 7 seconds.

Self-medication is unacceptable if you have cervical osteochondrosis. Only a doctor will help to cope with the problem.

Homeopathic remedies

There is a lot of controversy about the feasibility and effectiveness of ongoing therapy with homeopathic remedies. But every day more and more healing recipes appear. But one of the oldest and most frequently encountered is Golden Iodine. This tool is used for atherosclerotic lesions of the vessels of the brain, as well as in the presence of the consequences of acute cerebrovascular accident. “Golden iodine” is recommended if you have the following symptoms:

  • frequent headaches;
  • dizziness;
  • noise in ears;
  • memory impairment;
  • poor sleep;
  • violation of coordination of movements;
  • tremor of the limbs.

These funds are dispensed without a prescription and do not practically do any harm to the body. But monotherapy with such drugs is not recommended, it is best to take them in combination with other, more effective drugs.

Vitamins

The most famous vasodilator among vitamins is nicotinic acid (vitamin PP). This vasodilator drug helps relax smooth muscles by enhancing the production of prostaglandins. Also, nicotinic acid has a strong redox effect, which helps to improve the metabolism of nerve cells, increase their performance. This allows you to maintain cell activity at a normal level even with the development of hypoxic or hypoglycemic conditions.

For normal exposure to vitamin PP, it is used as an injection. During the injection, 1 ml of a % vitamin solution is slowly injected intravenously. This helps to achieve a quick vasodilating effect.

There are many adjuvants in the brain to stimulate blood circulation. Vitamins are an important component of complex therapy:

  • Ascorutin – a medicine with vitamin C and rutin is used to strengthen the walls of blood vessels for prevention.
  • Niacin is used strictly according to the doctor’s prescription, is used for electrophoresis, stimulates blood circulation in the brain with osteochondrosis.

Microcirculation correctors

The state of thin vessels helps to regulate such funds, health improves, dizziness stops, gait ceases to be shaky, signs of acute and chronic pathologies stop. The duration of the course of use is determined by the specialist, taking into account the severity of the disease. We list the main assets: Betaserk, Vestibo, Tagista.

Betagistin belongs to this category of drugs, it corrects blood flow in the capillaries, helps to cope with dizziness attacks, eliminates the unsteadiness of gait in chronic disorders. Tablets of 8 and 16 mg are taken in courses.

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The dosage is determined by the attending physician, divided into 3 doses per day. Medications are not prescribed for pregnant and lactating, carefully used for bronchial asthma, ulcerative formations.

Nootropic drugs are used to improve memory, promote metabolism in the formed elements of the brain. Thus, the activity of thinking is stimulated, information is better absorbed.

Regardless of the fact that evidence-based medicine has not yet approved this drug, in practical neurology drugs are used everywhere.

Similar drugs are used in the fight against vascular dementia in elderly citizens with encephalopathy or damage to brain vessels. It is pointless for young healthy patients to take these pills. Under the influence of nootropics, it is possible to transfer neurocyte membranes to a stable state, to improve the resistance of brain tissue to oxygen deficiency.

First of all, it is necessary to adhere to all the recommendations of the doctor, you do not need to prescribe and cancel the drugs yourself. It is necessary to ask the attending specialist about the possibility of playing sports, which exercises are allowed and which are prohibited. One of the main points is the normalization of the nutritional regime and diet.

Antispasmodics

Flavonoids

Vascular drugs help improve blood circulation in the brain, thanks to a strengthening and tonic effect. The body is freed from the effects of toxins. The list includes herbal medicines, the use of which the heart does not deteriorate. We list the main ones:

  • Ginkgo bilboa – eliminates spasms, stimulates microcirculation, eliminates puffiness, stabilizes pressure inside the skull.
  • Medications with a small periwinkle belong to the category of antispasmodics, prevent the formation of blood clots, stimulate blood flow. The doctor is authorized to prescribe such funds to people, they are not used for self-treatment because of the strong effect and several contraindications.

Nicotinic Acid Medicines

Among the potent drugs to stimulate blood circulation are drugs from nicotinic acid. The drugs do not affect large vessels, contribute to the expansion of capillaries, strengthen the walls, lower cholesterol.

It is necessary to use only on the recommendation of a specialist and under his supervision so that complications and side effects do not occur. Consider several popular drugs: Enduratin, Nikoshpan, Adipimox.

Vasodilators

Antispasmodics

Patients who are already over 70 should take into account nootropic drugs. They contribute to the saturation of the cell structure with blood and oxygen, contribute to better absorption of glucose. Efficiency, focus and memory are enhanced by increasing sugar levels.

You need to use medicines every day for a month. The next dosage should be reduced by 2 times. The result is felt a week after the start of the course.

The disadvantages of nootropics include addiction and the need to increase dosage. To prevent this from happening, experts advise taking small breaks in use and replacing drugs. For preventive purposes, in addition to nootropics, the following are acceptable for use:

  • Vitamin complex, remedies with ginseng extract.
  • Glycine helps get rid of the effects of scleosis, improves intellectual activity.
  • Piracetam stimulates the blood circulation, metabolism.
  • Tanakan improves intellectual activity, helps get rid of anxiety.

Signs of pathological changes in the vessels of the brain are:

  • headaches of varying intensity and localization;
  • dizziness;
  • problems with remembering;
  • fatigue;
  • bad hearing;
  • deterioration of vision;
  • inability to focus;
  • decreased sensitivity of the skin of the upper and lower extremities;
  • sudden short-term loss of consciousness.

Elderly people are especially prone to cerebrovascular accidents due to age-related changes, which are expressed both in a decrease in the tonus of the walls of blood vessels and in a narrowing of the lumen in them due to deposits. However, every year, young people suffer from both cardiovascular and neurological problems, suffering the consequences of terrible conditions of a heart attack or stroke, often ending sadly.

Injections

To strengthen the vessels, patients are often prescribed injections. In this way, the active components of the drugs enter the blood faster, tone the walls of the capillaries, give the maximum effect.

Injectable drugs are classified as follows:

  • Neutron drugs improve the functioning of nerve tissues.
  • Myotropic, improve muscle fibers.
  • Combined action.
  • Alkaloids-based drugs eliminate vasospasm, widen the lumen, increase metabolism, and help get rid of blood clots.
  • Medicines based on nicotinic acid act on the capillaries, help eliminate cholesterol plaques.
  • Vasodilating.

Antispasmodics

These tools help to expand the diameter of the vessels, relax the smooth muscle tissue of the capillaries. Such funds do not cause danger, act softly. They are used as pills for stimulating blood circulation and injections that belong to this group.

Such drugs do not effectively affect the vessels under the influence of atherosclerosis. They contribute to the redistribution of blood circulation, activating in healthy areas in which the blood vessels are better preserved. Therefore, problem areas of the brain are not adequately supplied with blood.

Alpha blockers

If vascular agents are used to stabilize blood circulation in the brain from such a subgroup, blood vessels can expand without damage to blood circulation. Such funds are used for cervical osteochondrosis. Often there is a stabilization of microcirculation.

Drugs in this group have a side effect, significantly lower blood pressure. Medicines are used only as directed by a doctor in the indicated dosage.

Alpha-adenoblocker drugs not only contribute to the expansion of capillaries, but also improve the metabolic process in the brain tissues, contribute to better platelet aggregation.

Tatyana Jakowenko

Editor-in-chief of the Detonic online magazine, cardiologist Yakovenko-Plahotnaya Tatyana. Author of more than 950 scientific articles, including in foreign medical journals. He has been working as a cardiologist in a clinical hospital for over 12 years. He owns modern methods of diagnosis and treatment of cardiovascular diseases and implements them in his professional activities. For example, it uses methods of resuscitation of the heart, decoding of ECG, functional tests, cyclic ergometry and knows echocardiography very well.

For 10 years, she has been an active participant in numerous medical symposia and workshops for doctors - families, therapists and cardiologists. He has many publications on a healthy lifestyle, diagnosis and treatment of heart and vascular diseases.

He regularly monitors new publications of European and American cardiology journals, writes scientific articles, prepares reports at scientific conferences and participates in European cardiology congresses.

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