Various liver pathologies are almost always accompanied by a decrease in albumin, which is due to a decrease in their production and an increase in beta and gamma globulins. Such changes are explained by the fact that albumin is produced by hepatocytes (liver cells), and the affected tissue cannot produce enough albumin.
The simultaneous increase in globulins (with a decrease in albumin level) is due to the fact that the synthesis of these compounds is provided to a large extent by other blood components, namely, cells of the tissue macrophage system. From which it follows that the underlying causes leading to an increase in the coefficient of thymoloveronal test are liver pathologies with a violation of its structure, namely:
- cirrhosis of the liver;
- viral and infectious hepatitis;
- benign and malignant tumors developing in the liver;
- damage to the liver parenchyma with alcohol and their substitutes;
- toxic effects of harmful substances, salts of heavy metals, as well as drugs;
- fatty hepatosis – the accumulation of fat in the liver cells;
- liver dysfunctions associated with prolonged use of oral contraceptives and other hormonal agents.
Reference! It should be noted that obstructive jaundice, although a pronounced sign, does not lead to thymol opacification. The Maclagan test will be high only in a situation of involvement of the parenchyma in the pathological process and the occurrence of inflammation in the liver tissue.
- severe forms of renal pathologies (glomerulonephritis, pyelonephritis, amyloidosis), in which a lot of protein comes out constantly with urine;
- digestive system diseases (pancreatitis, enteritis, accompanied by pronounced diarrhea);
- oncological neoplasms of a benign and malignant nature, regardless of their location;
- pathological conditions caused by a viral infection;
- genetically determined dysproteinemia (an imbalance between plasma proteins);
- systemic diseases – systemic lupus erythematosus, dermatomyositis, rheumatoid polyarthritis;
- septic endocarditis (with rheumatism, clouding is not determined, but is fixed in the normal range);
- myeloma, malaria.
Also, do not ignore another reason for the increase in the performance of the Maclagan test – excessive consumption of fatty foods. The appearance of turbidity in this case is not associated with the presence of the disease. To bring the indicators back to normal, just reconsider the diet.
Otherwise, such well-being, that is, the absence of the disease, will not last for a long time, since it is highly likely that another problem will develop – cholesterol growth and lipid disturbance. Low density lipoproteins accumulated in the blood will sooner or later be deposited on the vascular walls, forming atherosclerotic plaques, which will entail the development of atherosclerosis and all the troubles that accompany this disease.
Constantly increased coefficients of thymoloveronal test in the absence of clinical signs of any disease are a clear signal about the need to review the diet and reduce the consumption of fatty foods.
What is thymol test
For a correct assessment of the condition and functioning of the systems of internal organs, doctors recommend a biochemical blood test. Most often, you have to resort to his help if you suspect a pathology of the kidneys, liver or as a result of a violation of salt metabolism.
One of the options for a biochemical test is a thymol test. It allows you to determine the ability of the liver to synthesize protein compounds.
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To understand what this analysis is, you need to understand its essence. The bulk of the proteins in the blood is formed in the elements of the liver. They account for many varied tasks:
- active participation in the regulation of blood coagulability;
- maintaining oncotic pressure and ensuring the volume of the main body fluid;
- preservation of blood pH;
- transportation to tissues of certain categories of elements (e.g. cholesterol).
Blood serum has a diverse composition. However, only 5 protein fractions are considered important components. These are various globulins.
Under the influence of certain factors, their number may decrease or increase. For example, against the background of an impaired liver performance or malnutrition, the number of albumin is sharply reduced. An increase in globulins occurs with connective tissue pathologies, infectious processes of various etiologies, and some oncological ailments.
By thymol breakdown, it is customary to understand a special biochemical study. It allows you to get information about the ability of the liver to carry out a full synthesis of protein fractions.
The analysis helps to assess serious violations in the body’s work even before the onset of the initial signs of an ailment.
The principle of laboratory research is reduced to the precipitation of whey proteins. If a clouding of the substance is observed, they say a positive test result. The degree of change in the appearance of the material is determined by the photocolorimetric method, and is expressed in the so-called Maclagan units (unit M.).
The physicochemical characteristics of this analysis remain poorly understood. However, scientists argue that during the reaction complex complexes of phospholipids and globulins, thymol, and cholesterol are possible.
A blood test is recommended in the morning. About 8 hours before the proposed procedure, it is better to follow a starvation diet. It is allowed to drink only plain still water. Strong coffee or tea, juices should not be consumed in large quantities.
When it comes to the liver, everyone understands the importance of this organ. Without his help, one cannot imagine the full-fledged work of the body. Therefore, it is so important to periodically undergo preventive examinations, take blood tests. That thymol test is most often the main indicator of the quality of the liver.
Among the other advantages of this analysis are the following:
- does not require the use of expensive or complex equipment, material costs are negligible;
- characterized by simplicity in execution;
- allows you to identify many ailments at an early stage, to avoid complications and even death;
- can be used as a kind of indicator of ongoing therapy.
Modern medicine offers a wide range of different diagnostic tests. Among all the diversity, a special place belongs to the thymol test. It is one of the main tests that identify pathological liver disorders.
The initial decryption of the sample is quite simple:
- If the analysis column contains 0–5 units, it should be considered negative. Such indicators indicate that there are no serious violations in the composition of the serum.
- When the result is more than 5 units, the test is considered positive. The norm in men, women and children is the same.
As a rule, decoding the sample does not cause special difficulties for qualified physicians. If the protein component of serum is not accompanied by any major changes, they say a negative result. Moreover, the sample should be less than 5 units.
A positive response often indicates developing hepatitis. It is noteworthy that through this analysis, you can diagnose this serious ailment even before its primary manifestations. A positive test is also possible when bilirubin and aminotransferases remain within the regulatory options.
The norm of the thymol test in babies is exceeded if they have previously been diagnosed with hepatitis A. The pathology of group B is rarely accompanied by an increase in the indicator relative to the norms accepted in medicine.
A positive test option sometimes indicates that a small patient has already had hepatitis previously. In this case, the test is considered a kind of beacon of the dynamics of normalization of the liver.
If obstructive jaundice is progressing in an adult, thymol test responses are most often negative. However, in the event of complications in the form of parenchymal inflammation, a change in the results is possible.
When evaluating a test for a sample, a specialist should not forget that normative indicators are determined by the following parameters: patient’s age, approximate weight, and time for diagnosis. When deciphering the test, you also need to take into account that some pharmaceuticals can affect its parameters.
Despite the probable errors, the thymol test is even today considered one of the most informative studies. You have to resort to his help quite often. The thing is that it allows you to diagnose liver disorders in the initial stages and choose the right therapy.
An increase in indicators usually indicates a developed dysproteinemia. This condition is characterized by a change in the structure of serum at the protein level. At the same time, its quality characteristics are affected. These elements are expressed in 5 fractions. Each of them is distinguished by both chemical and physical properties.
Albumins belong to the category of the lightest fraction. It is characterized by the ability to maintain a stable state of the so-called colloidal blood system. Globulins are distinguished by a slightly larger mass and a tendency to precipitate.
Changes in the equilibrium in the colloidal system and the tendency of proteins to inevitably coagulate can be caused by disorders such as:
- Reducing the number of albumin.
- Increased alpha globulin concentration.
- The presence of paraglobulins in the blood (in a healthy person, they should be absent).
The listed pathologies can be identified precisely through a thymol test. The primary organ in which enhanced protein production usually occurs is the liver.
With severe failures in her work, a change in the characteristics of the blood is observed, and the thymol test shows the excess of certain parameters.
On the other hand, a positive analysis response is possible with extensive skin burns. Exceeding the globulin fraction indicators is also diagnosed in infectious processes, autoimmune disorders and rheumatoid disorders.
A few years ago, the main reasons for the increase in thymol test were considered solely from the point of view of impaired liver function. Today, the opinions of scientists have changed dramatically. Now, experts identify a number of diseases, the development of which accompanies the state of dysproteinemia.
Among them, it is worth noting the following:
- Disorders of the kidneys, characterized by the loss of albumin protein along with excreted urine.
- Pathologies of the liver, which manifest themselves in the form of cirrhosis, hepatitis or neoplasms.
- Systemic rheumatoid ailments.
- Gastrointestinal system diseases.
- The presence of neoplasms of malignant etiology.
The thymol test is sometimes elevated due to malnutrition. Typically, this problem is diagnosed in women. Excessive fatty foods can lead to a change in indicators. That is why during the diagnostic examination it is important to take into account other options for blood tests.
If a child’s thymol test is increased – what does this mean? As a rule, a similar result indicates the development of disorders in the liver.
At a young age, the presence of such diseases is extremely undesirable, since they may affect the work of the whole organism in the future. In children, they are manifested not only by a decrease in immunity, but also by a delay in mental development.
Today, in small patients, the following liver diseases are most often detected:
- Jaundice of the newborn. It manifests itself within a few hours after the baby is born. For this pathology, staining of the skin in yellow is characteristic. Its development is due to the fact that by the time of birth, the baby’s liver did not have time to finally form. Therefore, she is not yet ready to perform all functions. Among the main causes of the disease, doctors call bilirubin. It is formed against the background of the destruction of old red blood cells. If this pigment begins to accumulate in the body of the crumbs, the skin acquires the appropriate color. With timely diagnosis of the disease, it is possible to get rid of it without serious consequences after 7-10 days.
- Hepatitis of groups A and E. Disease of these types in young patients causes persistent disturbances in the functioning of the main systems of internal organs.
By what signs can a problem be suspected:
- First of all, the child begins to feel sick. Sometimes vomiting does not stop for several hours.
- Then there are painful sensations in the liver area.
- Fecal stains become white, and urine acquires a dark shade.
If these symptoms appear, you should immediately seek medical help.
After a comprehensive examination, the doctor will be able to make the correct diagnosis. Only after this treatment is prescribed. Therapy of various forms of hepatitis is carried out exclusively at home.
It is extremely important to isolate a sick child from peers. The main sign of recovery is a good blood count, the absence of pain.
Thymol test increased: causes, treatment and what does it mean
How to understand the fact that the thymol test is increased, the reasons? Could this somehow affect the general well-being, and indeed, what is it? Thymol test – part of a biochemical blood test.
A biochemical blood test, along with a general analysis, has long become a common way to diagnose diseases of a different nature.
This analysis is a set of manipulations with a blood sample aimed at determining the quantitative and qualitative characteristics of certain substances that make up the red liquid.
The composition of the biochemical analysis also includes the so-called thymol test. Why is it needed and what diagnosis can it talk about?
Thymol test – a blood test method invented in 1944 by McLgan. This method is based on the ability of a special solution to precipitate proteins in the liquid component of the blood when placed in a veronal buffer.
The results of the thymol test strongly depend on the state of the liver, so for quite a long time it was considered that this method can diagnose liver diseases, such as:
However, it later turned out that an increase in the response to thymol is also possible in the presence of other pathologies in the body. When setting up the study, an alcoholic mixture of thymol in a verolane test tube is taken as a nutrient medium. It is first added to saline, then a specially prepared emulsion from the patient’s blood plasma is let into the same solution.
In normal cases, the resulting mixture becomes slightly turbid, with the formation of a small amount of white flakes. If the patient is sick, the mixture acquires a pronounced white color. Thus, thymol interacts well with the blood plasma of patients with hepatitis, collagenosis and other ailments, which are characterized by dysproteinemia.
A normal indicator of a thymol test is considered to be readings from 0 to 4 units.
Accordingly, everything above 4 units is considered a deviation and is recognized as an increased thymol test, which indicates the likely presence in the body of a disease localized in the liver.
If the reaction to thymol is normal, this means that the protein component of the blood plasma is not broken, and you should not sound the alarm. But the fact that the thymol reaction is increased suggests the opposite – there are violations, and they must be eliminated.
The considered type of biochemical blood test is a high-precision method for detecting hepatitis in the body at the early stages of its development.
Since the thymol reaction shows how severely the synthesizing function of the liver is violated, with the help of it it is possible to detect hepatitis in the initial stages.
Indeed, albumin and transferase in these cases do not change their meaning.
One way or another, if the rate of thymol test relative to the nominal results is high, the attending physician must send the patient for an additional examination on suspicion of the following diseases:
- hepatitis of all types, cirrhosis, liver infiltration and impaired functioning due to steroids and contraceptives;
- renal pathologies, including those associated with the loss of albumin protein;
- malignant neoplasms;
- diseases of the digestive organs, in particular pancreatitis and enteritis:
- hereditary failures in protein metabolism.
The above pathologies can increase the thymol response. But in fact, there are many reasons, or rather, diseases, in which the thymol test is increased, and these reasons are sometimes weakly interconnected.
But still, the main factor in increasing the thymol test is liver disease. This follows from the fact that the sample itself uses the synthesizing abilities of the liver during its action.
So, now we know what the increase in thymol reaction indicates.
Another question is what to do if the sample is overestimated. Since this study in most cases determines the presence of pathologies of various nature, both mild and severe, the obvious solution for the patient will be to undergo an already more detailed medical examination, which will help to find out the exact diagnosis and determine a further plan of action. It is possible that a comprehensive treatment is required.
In addition, a thymol test can be used as an assessment of the benefits of an existing treatment.
For example, if a patient began to treat hepatitis A, then the considered method of biochemical analysis, assigned to the patient every time after a certain period of time, can show how effective the treatment is.
Thymol alcohol solution responds better to degraded liver proteins than other solutions used in medicine do.
Now the most promising direction of the thymol test is the diagnosis of the body for the detection of liver diseases, since it is in this area that this technique shows itself in the best way.
Even a slight increase in the result of the analysis is an indication for examining the liver, conducting virological tests for hepatitis, ultrasound of the abdominal organs, and sometimes a liver biopsy is also needed.
Treatment is prescribed taking into account the causes of violations of the liver. To restore it, you must:
- limitation of physical activity during exacerbation;
- minimum amount of medication;
- the exception of alcohol, fatty and fried foods;
- sharp restriction of canned food, smoked products, marinades, spicy sauces, spices and strong coffee, tea;
- provide protein from low-fat meat, dairy and fish products;
- include boiled vegetables, non-sour fruits in the menu.
To protect liver cells, a group of drugs called hepatoprotectors is used. These drugs prevent the destruction of hepatocyte membranes, accelerate the recovery of albumin synthesis. Usually they are prescribed in courses of 2 to 3 months at least twice a year. The most effective are Essentiale forte N, Heptral, Glutargin, Hepa-Merz, Gepadif.
In case of viral hepatitis, interferon is administered intramuscularly or intravenously in combination with antiviral drugs (ribavirin), and also new long-acting interferons (pegylated) are used – Pegasis, Algeron. If hepatitis is caused by an autoimmune process, hormone therapy is indicated.
The thymol test is highly sensitive to liver damage, especially with viral hepatitis A. It helps to identify it in the preclinical stage. A positive result also occurs with infectious, autoimmune, tumor processes in the body. Differs in speed of carrying out, it is recommended for control of treatment. In case of a deviation from the norm, an additional examination and compulsory treatment, dietary compliance are indicated.
With an increase in thymol test, the most common cause is liver disease. For this reason, to normalize the indicators of analysis, it is first necessary to accurately identify the cause of the change in the state of blood proteins. And depending on the diagnosis, the doctor will prescribe the appropriate treatment
However, besides him, with an increase in thymol test indices, it is necessary to adhere to a special diet. It consists in limiting the patient’s intake of fatty foods, regardless of whether they are animal or vegetable.
In addition, it is necessary to exclude from the diet fast carbohydrates, some sour fruits, citrus fruits, tomatoes, soups based on meat or fish, broths.
A biochemical blood test is a comprehensive study that allows you to identify functional disorders of various organs and systems.
In its framework, a thymol test is also carried out in order to detect liver pathologies. It still has not lost its diagnostic value, although today advanced modern methods are more often used.
This test has several names: Maclagan test, thymoloveronal or thymol turbidity. Proteins of various types, responsible for the formation of the immune response, osmotic characteristics of the blood and other indicators, are produced by cells of the liver and bone marrow. The ratio of albumin and globulin changes with damage to hepatocytes, as does the structure of proteins that lose colloidal stability and precipitate.
Thymol test as a method for assessing the functional state of the liver was proposed back in 1944. To date, it is used quite rarely, mainly according to the indications for the development of hepatitis A symptoms in combination with other tests. It is also used in toxicology and hepatology to assess the positive dynamics of the recovery process in the liver after diseases.
What is thymol test?
Thymoloveronal test, thymol clouding test, Maclagan test – synonyms of thymol test, biochemical test, which refers to coagulation samples. It was proposed in 1944. Sometimes coagulation tests are also called colloidal reactions, the essence of which is to show the ratio of blood proteins, or rather to detect an increased amount of globulins relative to albumin.
Proteins synthesized in the liver perform many different and important functions in our body. For example, they provide transport of cholesterol, bilirubin, drugs, support oncotic pressure, blood pH, and others.
There are 5 fractions of serum proteins: albumin and globulin – alpha-1, alpha-2, beta, gamma. Gamma and beta-globulins interact with thymol in a veronal buffer, which causes turbidity of the solution or precipitation (a globulin-thymolipid complex is formed, Fig. 1). The essence of the thymol test is to determine the degree of turbidity of serum using special equipment – photoelectrocolorimeter (FEK).
Turbidity is expressed in units of Maclagan (units M.) or Shank-Hoaland (units SH).
A decrease in the concentration of albumin occurs in violation of the protein synthesizing function of the liver. This leads to instability in the level of globulins. This occurs with infectious, tumor processes, liver diseases.
This type of biochemical analysis is not popular, but due to its advantages it is still used in practice.
The benefits of the test are as follows.
- Thymol testing does not require sophisticated equipment. Only a photoelectric colorimeter is needed to determine the turbidity, which is in any laboratory.
- Research is easy to do and cheap.
- Despite the existing choice of markers of liver damage, it is the thymol test that will indicate the beginning of the development of the pathological process even before the development of clinical symptoms, which allows the doctor to prescribe treatment on time and avoid the development of complications.
- The thymol test can be used as an indicator of the effectiveness of the restoration of liver cell function.
The norm of thymol test in women in the blood
- fatty foods on the eve of the analysis;
- recent administration of drugs with toxic effects – antibiotics, antifungal agents, chemotherapy;
- hormonal contraception, estrogen replacement therapy.
A biochemical blood test is a comprehensive study that allows you to identify functional disorders of various organs and systems. In its framework, a thymol test is also carried out in order to detect liver pathologies.
It still has not lost its diagnostic value, although today advanced modern methods are more often used.
What is the study, what diseases cause a positive reaction, how the analysis is given and transcribed – the answers to all questions in the article.
This test has several names: Maclagan test, thymoloveronal or thymol turbidity.
Proteins of various types, responsible for the formation of the immune response, osmotic characteristics of the blood and other indicators, are produced by cells of the liver and bone marrow.
The ratio of albumin and globulin changes with damage to hepatocytes, as does the structure of proteins that lose colloidal stability and precipitate.
Contacting various types of globulins and low density lipoproteins, the reagent causes turbidity, the degree of which allows us to judge the violation of protein synthesis in hepatocytes. The result is measured in ED Maclagan or Shank-Hoaland (abbreviated units M and ED SH, respectively).
Thymol test as a method for assessing the functional state of the liver was proposed back in 1944. To date, it is used quite rarely, mainly according to the indications for the development of hepatitis A symptoms in combination with other tests.
It is also used in toxicology and hepatology to assess the positive dynamics of the recovery process in the liver after diseases.
It helps to differentiate different types of jaundice, since with Botkin’s disease (type A) in almost 100% of cases it gives a positive result, and with a mechanical one it is always negative.
Normal indicators of the study depend on the correctness of the test. This should be done on an empty stomach in the morning, but it is allowed to drink water before the test. When applying the study against the background of drug therapy
, before the test, the doctor should be notified about the use of drugs so that he can make an adjustment for distortion of the results.
In women, the normal thymol test is up to 5 units M. However, with dysproteinemia and oral contraceptives, the norm rises. If the indicator is increased outside these conditions, then a high probability of malfunctioning of the liver. The test itself allows you to identify the stability of proteins, depending on the indicators, health problems are identified.
An increase in the indicator may not be diagnosed with obstructive jaundice
, only with the transition of the disease to a more serious stage and with the development of inflammation, a problem can be diagnosed.
In addition to jaundice, the absence of a positive result of the thymol test can be observed with a difference in the natural ratio of alpha and beta globulins, in the presence of significant overweight or underweight.
It should be noted that with the development of hepatitis B in humans, the thymol test does not give a positive result, since its result will vary from 1 to 5 units.
., this is not a deviation from normal performance.
As such, gender differences cannot affect the test result. Specific male and female hormones do not influence the process of protein synthesis in liver cells. Therefore, for the fair sex, normal test parameters are the same as for men: 0-4, a maximum of 5 units of turbidity.
However, the use of contraceptives (oral contraceptives) by a healthy young woman can have a definite effect on protein synthesis. Under the influence of drugs of this type, the ratio of plasma proteins changes, which leads to a slight increase in indicators.
The norm of thymol test in men
- Normally (the test result is negative), the thymol test in men and women is in the range of 0-5 units. M (Maclagan units). This means that there are no violations in the composition of serum proteins;
- If the result of thymol test exceeds 5 units. M, such violations occur.
Thymol test is of great importance in the early stages, when the first signs of its defeat are still missing. This test is important for diagnosing viral hepatitis or identifying erased forms of the disease.
- The thymol test is significantly increased with hepatitis, as well as with cirrhosis, when the liver cells are replaced by connective tissue;
- In hepatitis due to chronic alcoholism, heavy metal poisoning, drugs (antihistamines, antitumor, antidiabetic, diuretic, hormonal, antibiotics and antidepressants), the liver ceases to synthesize proteins normally, so the thymol test is also positive;
- In the early stages of obstructive jaundice caused by a violation of the outflow of bile, the thymol test is usually negative, but with a long process, liver tissue is affected, and it becomes positive;
- The thymol test is positive for hepatitis provoked by such infectious diseases as mononucleosis, leptospirosis, brucellosis, as well as acute fatty liver atrophy, autoimmune hepatitis, and liver tumors;
- Thymol test is positive not only in cases of liver damage. accompanied by nephrotic syndrome, it is also elevated;
- This indicator is recorded with an increase in systemic diseases such as systemic lupus erythematosus, systemic scleroderma, rheumatoid arthritis, dermatomyositis, periarteritis nodosa, hemorrhagic vasculitis;
- In addition, an increase in thymol test is noted with pancreatitis, malaria, malignant neoplasms, myeloma and even excessive consumption of fatty foods.
Thus, it is impossible to make a diagnosis with one thymol sample. Patients can only be evaluated in combination with other research methods.
To assess the functional state of various organs and systems of the human body, doctors prescribe a biochemical blood test. Its results make it possible to correctly diagnose, prescribe appropriate therapy, and also adjust the treatment plan if necessary. As a rule, a biochemical analysis is prescribed for suspected damage to the liver, kidneys, impaired water-salt metabolism, as well as in the presence of an active inflammatory process.
The turbidity of the solution upon binding of the reagent to the globulin fraction may have different severity. The specific value in units of Maclagan or S-H is determined using a special instrument of an electrospectrophotometer. In a healthy man, the indicators should be between 0 and 4. However, some laboratories set an upper limit of the reference value of 5 units. M.
A biochemical blood test is used in the diagnosis of many diseases. Thymol test is one of the indicators that is investigated during this analysis.
It shows the ability of the liver to synthesize protein compounds. However, deviations of indicators from the norm do not always indicate liver pathology. There are many reasons why the values of a thymol sample vary.
Consider what a thymol test is in a biochemical blood test.
A thymol test is an indicator that shows the ratio of proteins (albumin and globulin) in human blood. With its help, you can easily detect a violation of this balance, which always accompanies the pathological process that occurs in the liver.
This test has been used in medicine since 1944. For its implementation, the patient’s blood plasma and a special reagent – an alcohol mixture of thymol are needed. In a verolan tube, saline, thymol mixture, and plasma are combined.
In this case, the degree of turbidity of the contents of the tube is evaluated. Normally, the turbidity of the resulting solution is weakly expressed, and in the presence of a certain pathology, it becomes white with a large amount of flakes (precipitate).
The degree of turbidity of the mixture is estimated by an electric photocolorimeter. The unit of measure is “maclagan”. It is so named after the scientist who invented the thymol test.
In the absence of pathology associated with a violation of the concentration of protein formations in the blood, the thymol sample does not go beyond the normal range, that is, does not exceed them. It should be noted that the limits of the norm are the same for all people and does not depend on the gender and age of the patient.
Slight clouding of the solution during the test corresponds to values from 0 to 4-5 units of Maclagan. These values are considered negative, that is, the ratio of proteins in the blood is not broken.
If the result of the study exceeds 5 units, then it is considered that the test is positive and there is a disease of the liver and other internal organs, proceeding in acute or chronic form. Upon receipt of such an analysis result, it is necessary to undergo an additional examination in order to identify the causes of dysproteinemia, that is, imbalance of proteins in the human body.
It should be noted that in women a false-positive result may be noted. That is, the test is positive (more than 5 units), and there are no pathologies.
This is possible in the case when the representative of the fair sex for a long time takes hormonal oral contraceptives.
Therefore, the doctor should clarify this point before referring the patient to a laboratory test.
It should be remembered that in the laboratory only the calculation of indicators is carried out. The evaluation of the result is carried out by the attending physician. At the same time, he must take into account factors that can affect the result:
- Patient weight;
- Previous diseases;
- The use of certain groups of drugs that can have a certain effect on the liver and its indicators.
If the result is negative, then the patient is healthy. If deviations from the norm are noted, then the doctor should find out the etiological factors of this condition.
What should be considered when evaluating a positive result:
- In young children, an anamnesis must be taken into account, since a high result may be a consequence of recently transferred hepatitis A. In this case, using this test, you can easily monitor the degree and speed of restoration of liver function. Over time, indicators decline and then normalize;
- In an adult, this indicator may be the first sign of a severe liver pathology. The test becomes positive even before the appearance of pathological symptoms, which makes it possible to >
It is important to know that with the development of obstructive jaundice without inflammation, the thymol test remains negative.
An increase in values is observed in violation of the ratio of proteins in the blood. At the same time, the level of albumin decreases, but globulins, on the contrary, increase. Also in the blood of a sick person, paraglobulins are found that are not in the body of a healthy person.
The reasons why the thymol test is increased:
- Liver pathology: hepatitis, cirrhosis, tumors of various nature;
- Diseases of the gastrointestinal tract, accompanied by dyspeptic disorders (in other words, diarrhea): pancreatitis, enteritis;
- Kidney disease in which albumin is excreted in urine in large quantities: pyelonephritis, glamerulonephritis;
- Systemic rheumatic diseases;
- Malignant tumors of various localization;
- Improper nutrition, in which there is a lack of nutrients.
In young children, deviation of the test results from the norm is noted in the following cases:
- Jaundice of the newborn. This condition is associated with a large load on the baby’s liver in the first days after birth. As a rule, this condition is physiological and passes through 1 – 2 weeks;
- Hepatitis A – a viral lesion of the liver. In most cases, a full recovery and restoration of organ functions is recorded.
First of all, it is necessary to undergo a full examination and, after identifying the cause, proceed to the treatment of the disease. Etiological treatment will depend on the pathology, and is aimed at restoring the functions of the affected organ. In severe cases (in the presence of malignant neoplasms), surgical treatment is indicated.
In addition to drug treatment, diet is of great importance. In this case, experts recommend:
- Reduce the consumption of animal and vegetable fats;
- Completely refuse fatty, fried, salty and canned foods;
- Confectionery, sour berries and fruits, tomatoes, meat and fish broths are excluded from the diet;
- Preference is given to mucous soups and porridges on the water, it is better to use vegetables in boiled, stewed or baked form, low-fat boiled meat and steam cutlets;
- Limit salt intake
- Coffee, strong tea and alcohol are excluded.
A biochemical blood test is prescribed if there is a suspicion of the presence of:
- Pathology of the digestive tract;
- Impaired renal function;
- Diseases of the joints and blood vessels;
- In young children with prolonged persistent jaundice of newborns.
A thymol test is also provided during and after treatment to evaluate its effectiveness.
To ensure the reliability of the result, it is necessary to properly prepare for blood donation:
- A few days before the test, refuse to eat fatty and fried foods;
- On the eve of the study, make a light dinner no later than 20:00;
- On the day of blood sampling, you should not eat or drink drinks other than water. The study is carried out on an empty stomach in the morning.
For the test, it is necessary to take venous blood, which is mixed with reagents. This mixture is examined after 30 minutes using a photocolorimeter. The patient can get the result the very next day after blood donation.
The measurement results are given in units of Maclagan – from 0 to 5 units. M. In the range of up to 4 units, the thymol sample is considered negative. This norm does not distinguish between sex or age. A positive test is at 5 units. M (sometimes the designation in ED SH is used).
Detonic – a unique medicine that helps fight hypertension at all stages of its development.
The complex effect of plant components of the drug Detonic on the walls of blood vessels and the autonomic nervous system contribute to a rapid decrease in blood pressure. In addition, this drug prevents the development of atherosclerosis, thanks to the unique components that are involved in the synthesis of lecithin, an amino acid that regulates cholesterol metabolism and prevents the formation of atherosclerotic plaques.
Detonic not addictive and withdrawal syndrome, since all components of the product are natural.
Detailed information about Detonic is located on the manufacturer’s page.